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25 Cards in this Set

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PACO2
Partial pressure of carbon dioxide
Right-to-left anatomical shunts
anatomical bypass in which blood flows from the venous to arterial side of the circulation, bypassing the lungs. This lowers both the oxygen content and the PO2 of the arterial blood.
Venous admixture
Mixing of venous blood w/ arterial blood, resulting in a decrease in oxygen content of the latter; occurs in anatomical and physiologic shunting.
Fick Equation
A formula for computing cardiac output based on knowledge o oxygen consumption and the arterial-venus oxygen content difference.
Qt=Vo2/[c(a-v)O2x10]
Fick's first law of diffusion
The greater the surface area, diffusion constant, and pressure gradient, the more diffusion will occur.
Oxyhemoglobin
(HBO2)
Chemical combination resulting from the covalent bonding of oxygen to the ferrous iron pigment in hemoglobin
Bohr Effect
The Impact of changes in blood pH on Hb affinity for oxygen.
Acidity
Low Ph
Alkalinity
High PH
Methemoglobin b
(metH
an abnormal form of the molecule, in which the heme-complex normal ferrous iron ion loses an electron and is oxidized to its ferric state.
methemoglobinemia
a special form of anemia resulting form metH.
Carboxyhemoglobin
(HbCO)
the chemical combination Hb w/ Carbon monoxide.
P50
the partial pressure of oxygen at which the Hb is 50% saturated.
Haldane Effect
The influence of oxyhemoglobin saturation on carbon Dioxide dissociation. A result of changes in the affinity of Hb for CO, which occur as a result of its buffering of H+ ions.
Hypoxia
Oxygen deliver falls short of cellular need.
1) the arterial blood oxygen content is decreased.
2) cardiac output or perfusion is decreased. (shock or ischemia)
3) adnormal cellular function prevents proper uptake of oxygen.
Hypoxemia
When the partial pressure of oxygen in the arterial blood (PaO2) is decreased to lower than predicted normal based on the age of the patient.
Dysoxia
a form of hypoxia in which the cellular uptake of oxygen is abnormally decreased.

Example: Cyanide Poisoning.
Ventilation/perfusion ratio (v/Q)
the ration of fulmonary alveolar ventilation to pulmonary capillary perfusion, both measured quantities being expressed in the same units.
Carboxyhemoglobin
(HbCO)
A compound produced by the chemical combination of hemoglobin with carbon monoxide.
Dysoxia
An Abnormal metabolic state in which the tissues are unable to properly use the oxygen made available to them
fetal hemoglobin (HbF)
A hemoglobin variant that has a greater affinity for oxygen than does adult hemoglobin; HbF is gradually replaced over the first year of life by HbA
Alveolar Shunt
Alveoli that receive blood flow from pulmonary capillaries, but do not receive gas flow.
Haldane effect
The influence of hemoglobin saturation with oxygen on CO2
hamburger phenomenon
The movement of chloride ion into the erythrocyte to balance the electrical charge of bicarbonate moving outside of the erthrocyte
sickle cell hemoglobin
An abnormal hemoglobin which can become sickle-shaped and plug small capillaries as well as result in the destruction of the erythrocyte which makes less hemoglobin available.