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25 Cards in this Set
- Front
- Back
PACO2
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Partial pressure of carbon dioxide
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Right-to-left anatomical shunts
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anatomical bypass in which blood flows from the venous to arterial side of the circulation, bypassing the lungs. This lowers both the oxygen content and the PO2 of the arterial blood.
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Venous admixture
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Mixing of venous blood w/ arterial blood, resulting in a decrease in oxygen content of the latter; occurs in anatomical and physiologic shunting.
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Fick Equation
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A formula for computing cardiac output based on knowledge o oxygen consumption and the arterial-venus oxygen content difference.
Qt=Vo2/[c(a-v)O2x10] |
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Fick's first law of diffusion
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The greater the surface area, diffusion constant, and pressure gradient, the more diffusion will occur.
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Oxyhemoglobin
(HBO2) |
Chemical combination resulting from the covalent bonding of oxygen to the ferrous iron pigment in hemoglobin
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Bohr Effect
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The Impact of changes in blood pH on Hb affinity for oxygen.
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Acidity
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Low Ph
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Alkalinity
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High PH
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Methemoglobin b
(metH |
an abnormal form of the molecule, in which the heme-complex normal ferrous iron ion loses an electron and is oxidized to its ferric state.
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methemoglobinemia
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a special form of anemia resulting form metH.
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Carboxyhemoglobin
(HbCO) |
the chemical combination Hb w/ Carbon monoxide.
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P50
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the partial pressure of oxygen at which the Hb is 50% saturated.
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Haldane Effect
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The influence of oxyhemoglobin saturation on carbon Dioxide dissociation. A result of changes in the affinity of Hb for CO, which occur as a result of its buffering of H+ ions.
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Hypoxia
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Oxygen deliver falls short of cellular need.
1) the arterial blood oxygen content is decreased. 2) cardiac output or perfusion is decreased. (shock or ischemia) 3) adnormal cellular function prevents proper uptake of oxygen. |
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Hypoxemia
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When the partial pressure of oxygen in the arterial blood (PaO2) is decreased to lower than predicted normal based on the age of the patient.
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Dysoxia
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a form of hypoxia in which the cellular uptake of oxygen is abnormally decreased.
Example: Cyanide Poisoning. |
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Ventilation/perfusion ratio (v/Q)
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the ration of fulmonary alveolar ventilation to pulmonary capillary perfusion, both measured quantities being expressed in the same units.
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Carboxyhemoglobin
(HbCO) |
A compound produced by the chemical combination of hemoglobin with carbon monoxide.
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Dysoxia
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An Abnormal metabolic state in which the tissues are unable to properly use the oxygen made available to them
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fetal hemoglobin (HbF)
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A hemoglobin variant that has a greater affinity for oxygen than does adult hemoglobin; HbF is gradually replaced over the first year of life by HbA
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Alveolar Shunt
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Alveoli that receive blood flow from pulmonary capillaries, but do not receive gas flow.
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Haldane effect
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The influence of hemoglobin saturation with oxygen on CO2
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hamburger phenomenon
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The movement of chloride ion into the erythrocyte to balance the electrical charge of bicarbonate moving outside of the erthrocyte
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sickle cell hemoglobin
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An abnormal hemoglobin which can become sickle-shaped and plug small capillaries as well as result in the destruction of the erythrocyte which makes less hemoglobin available.
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