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36 Cards in this Set

  • Front
  • Back
Pathway of light
from external starting at the cornea to internal (retina)



light enter through cornea, aqueous humor & pupil, crystalline lens, vitreous humor and the converges on the retina

Average length of healthy adult eye
2.42 cm
fixed refracture power of the cornea
43 diopters (70% of total refractive power of the eye)
refractive power of the natural lens
20 diopters
Myopia
nearsightedness

caused by a highly steep cornea or long distance between cornea and the retina




light rays come up short.




muscle weakness

Hyperopia
Farsightedness

caused by a shorter distance from cornea to the retina




light rays go too far

Astigmatism
when cornea curvature is more oval than round.



Both distant and near vision are affected

Role of additives in contact lenses
copolymerized in the contact lens material to protect eye from harmful effects of UV light



UV light is harmful to retina and contributes to cataract

catarct
clouding or discoloration of the lens

one of the most common eye disease

Optical devices
good transmission of visible light and ultraviolet light-absorbing
Important properties of contact lenses
oxygen permeability

hydrophilic

Materials to make contacts
polydimethylsiloxans PDMS

polymethyl phenyl vinyl silosanes PMPVS




silicon rubber is hydrophobic so must be treated with an RF-plama reactor to make surface hydrophilic (not good material)

Standard Hydrogel Contact Lenses (SHCLs)
homogeneous hydrogel

material: poly(2-hydroxethylmethacrylate) (PHEMA), 40% of water hydration in physiological saline solution




Advantages: fit snugly to cornea, increase coefficient of oxygen permeability with water content




complications: oxygen transmissibility of oxygen decreases with increasing thickness



4 groups of FDA classified hydrogel lenses
1) low water (<50% H2O) nonionic

2) High water (>50% H2O) nonionic


3) Low water, ionic


4)High water, ionic

Siloxane-Hydrogel Contact Lense
Material: silicone and treated with RF-plasma reactor



Advantage: High O2 permeability




Complications:

3 layers of the cornea
1) Epithelium, outermost layer, 5 cell layer

2)Stroma, main portion. 78% hydrated in normal state


3) The endothelium, intermost layer, maintains hydration of the cornea

Hypoxia
an injury to the epithelial and endothelial membranes that disrupts normal corneal hydration
Describe a corneal transplant
cone-shaped cornea is removed and replaced with a donated cornea.



90% success rate (no blood in cornea)




60% still require glasses or contacts

Intracorneal Implants
used to correct vision



materials: hydrogel, silicone rubber




previous implants were made of PMMA or polysultane which resulted in ulcerations

Corneal Ring implants

half circle implants placed in the clear, dome-shaped bulge at the front of the cornea. (placed on the sides of the cornea)



materials: PMMA or silicon rubber



complications: infection, glare or halos, night vision problems and overcorrection or undercorrection

Corneal ring implants effect on curvature
steeper, increases the refractive power



flatter, decreases the refractive power

Keratomileusis
removes a section of the cornea, reshapes that section, and the replaces the reshaped section
Intrastromal Ablation
laser sculpts under surface to correct vision
Epithelial Implants

(Epikeratoprostheses

replaces irregular, swelling, and proliferated epithelium.



material: hard PMMA and glued with cyanoacrylate

Epikeratophakia
Impantation of artificail epithelial or transplant beneath the epithelium to increase the steepness of the cornea for correction of farsightedness
Artificial Endothelium
replaces corneal endothelium with silicon rubber membrane that passively controls hydration



a failure as it prevented cornea from receiving nutrient and water from aqueous humor

Removing cataract
cataract is removed, the lens of the eye is removed. An artificial lens into the eye to help it focus
age-related cataract
cataract related to aging
congenital cataract
born with cataract or developed in childhood. May or may not affect vision
Secondary cataract
cataracts developed because of medical problems or medications. Long-term unprotected exposure to sunlight may also lead to cataracts
Traumatic cataract
Develops soon after or years later after eye injury
Symptoms of a Cataract
-fading or yellowing of eye

-double or multiple vision in one eye, may go away as cataract grows


-needing brighter light to read


-cloudy or blurry vision


-poor night vision

Intraocular Lens Implants (IOLs)
10 million IOLs are implanted worldwide

used in cataract patients




Helps focus light, without it the person would be illegally blind after cornea removal

cararactous
lens of eye turns cloudy and optical images deteriorates. Eventually leads to blindness and is leading cause of blindness
LASIK for Nearsightedness
a thin flap of cornea is created and folded back

Excimer laser is applied to reshape the cornea


the cornea flap is replaced over the treated cornea


the flatter cornea now bends the light onto the retina

LASK for Farsightedness
a thin flap of cornea is created and folded back

Excimer laser is applied to reshape the cornea


the cornea flap is replaced over the treated cornea


the steeper cornea now bends the light onto the retina