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12 Cards in this Set

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  • Back
describe blood and its cellular and non cellular products
Blood is a fluid tissue because it has a matrix (plasma) and living blood cells known as formed elements.

Erythrocytes
Red blood cells
Transport oxygen

Leukocytes
White blood cells
Act in various ways to protect the body

Platelets
Cell fragments that help stop bleeding
what are the fxns of blood?
Transportation of Nutrients and Gases
Regulation (Homeostasis)
Protection
what is normal hematocrit?
45% RBC
<1% WBC and Platelets
55% Plasma
Females
42 + 5
Males
47 + 5
what does hemoglobin do?
Reversibly bind with oxygen on erythrocytes
Each hemoglobin molecule can transport _____ molecules of oxygen.
4 Molecules of Oxygen
describe coagulation and its various mechanisms
Coagulation reinforces the platelet plug with fibrin threads that act as a “molecular glue” for the aggregated platelets.
Follows intrinsic and extrinsic pathways

Steps
Prothrombin activator is formed.
Prothrombin is converted into thrombin.
Thrombin catalyzes the joining of fibrinogen into a fibrin mesh.
describe platelet plug formation
Platelets stick together and form a plug that temporarily seals the break in the vessel wall.

Steps
With the help of von Willebrand factor, the platelets adhere to collagen.
They are stimulated by thromboxane A2
Platelets stick to exposed collagen fibers and form a platelet plug.
Serotinin and ADP is released, which attract more platelets.
what is anemia?
Too few red blood cells lead to tissue hypoxia
Too many red blood cells cause undesirable ______ ________.
Blood Viscosity
describe leukocyte disorders
Myelocytic leukemia involves myeloblasts.

Lymphocytic leukemia involves lymphocytes.

Acute leukemia involves blast-type cells and primarily affects children.

Chronic leukemia is more prevalent in older people.
describe leukemia
Immature white blood cells are found in the bloodstream.

Bone marrow is occupied with cancerous leukocytes.

White blood cells that are produced are not functional.

Death is caused by internal hemorrhage and overwhelming infections.

Treatments:
Irradiation
Antileukemic Drugs
Bone Marrow Transplants
where is the blood cell formation completed in the fetus?
yolk sac