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28 Cards in this Set
- Front
- Back
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Where are 95% of HIV cases in the world?
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developing countries
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Why is Kaposi's not really a "sarcoma"?
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Because it is part of the HHV category
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What % of the 60% of sub saharan women are infected with HIV that are 15-24?
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77%
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What is the most prominant form of HIV?
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M
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Is HIV 2 as virulent as HIV1?
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NO
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What gene is responsible for the major structural protein of HIV (p24)?
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gag
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What is the HIV matrix protein that is coded by gag?
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p17
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What is the designation of reverse transcriptase that is coded by pol?
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p66
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Which protein coded by env resides on the outside of the HIV?
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gp120
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Which virus antigen spikes during the first 12 weeks post infection then falls to very low levels and finally begins to rise at the terminal end of the infection?
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p24
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Is there an initial spike in CD8 cell at the beginning of the infection?
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yes
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What do patients who have STDs, pneumococcal pnemonia, meningococcemia, disseminated gonorrhea, TB, zoster, oral candidiasis, and high risk behavior all have in common with regard to HIV?
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they should be screened
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What is the new CDC recommendation with regard to HIV screening?
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every 3-5 years, every 6 mos if at risk
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What is the order of screening?
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oral assay, then WB, then confirmation with PCR
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How often should viral load be checked?
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3-4x per year
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What are cross reactive and auto Abs that can cause false + results?
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HLA-DR, ther class II antigens and ANA, antimitochondrial Ab, respectively
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How can specimen handling cause false +?
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heat inactivation and freeze thaw cycles
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Can vaccines cause false +?
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yes, flu vacc
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Can pooled Ig cause false +?
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yes, IgG
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What is the ryan white act?
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spouses of HIV + patients must be notified
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What are two HIV scenarios that always require treatment?
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CD4<200 and viral load >100K
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What is the definition of AIDS?
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< or equal to CD4 200
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What fungoidal infection is generally treated at a CD4 <200< with Tmp/smx, dapsone, atovaquone, and pentamidine
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pneumocystis jiroveci
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What is the prophylaxis treatment for Toxoplasma gondii, at a CD4 <100?
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tmp/smx, dapsone
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When should mycobacterium avium prophylactic treatment with azithromycin 1200mg weekly begin?
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CD4 <50
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When should M. Tuberculosis treatment begin?
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TsT greater than or equal to 5 mm
Inh Pza/eth (limited only to hiv positive) |
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How many strep vaccines should be given in a lifetime?
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two, 5 years apart
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What gives a better response in strep pnemo prophylaxis?
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higher CD4 the better
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