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135 Cards in this Set
- Front
- Back
functions of the lymphatic system:
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two major functions
-immunity -to help maintain blood volume |
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lacteals
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located in the alveoli of the small intestine; specialized lymphatic capillaries found in the small intestine; pick up absorbed fats for transport.
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most nutrients are absorbed in the blood except
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lipids aka fats
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lipids are taken care of where
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in the liver
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lyphatic system: first main function
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to help maintain blood volume.
-when you have capillary beds some plasma leaks out you see some plasma gone due to : - osmotic pressure changing -hydrostic pressure changing if it happens arround tissue it is called edema. |
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when plasma escapes
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you get swelling called edema.
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interstintial fluid
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is composed of plasma, plasma electrolytes, plasma gases, is outside the blood stream and if it keeps accumulating you will get edema.
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lyphatic capillaries
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are the smallest structures in the lymphatic system, located in the interstitial fluid, and are there to pick up excess interstitial fluid so you dont get edema.
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lymphatic capillaries are made of
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simple squamous epithelial cells
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so the interstitial fluid is picked up by ___ and once it is picked up the name is now called ____
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lyphatic capillaries, lymph
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capillaries come together to larger things called
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lyphatic vessels
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lymphatic vessels
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are similiar to veins in the circulaory system, have tunics and valves, three layers , pass through several lymph nodes
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what filters lymph?
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lymph nodes
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lymphatic vessels are the only thing that can go through
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lymph nodes
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several lymphatic vessels may come togther to form larger vessels called
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lymphatic trunks and are named after the section of the body that they drain (abdomen).
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In the lymphatic system several trunks come back togther to form two main lymphatic ducts (two large structures)
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-right thoracic duct
-thoracic duct |
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thoracic duct
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longest and largest of two ducts; originates in the abdominal pelvic and runs into the chest cavity and brings the fluid from the legs up (lymph or plasma) returns to circulatory system and joins the left subclavian vein and empties here, (by left jugular vein) then dumped into the RA (oxygen poor side)
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right thoracic duct
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Right side version of the thoracic duct; starts and stops in the thoracic cavity and drains the head and neck; returns filtered plasma into the right subclavian vein.
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left subclavian vein
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is where the thoracic cavity empties, (by left jugualr vein), then dumped into the RA (oxygen poor side)
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what are the functions of the ducts
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to return filtered plamsa to the HEART
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lymph nodes info:
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has a convex surface and a concave surface, has one opening into the hilum, is living tissue which needs blood supply
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hilum
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opening into the lymph node on concave side (all blood supply enters here; arteries, veins, nerves...)
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concave lymph side
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afferent lymph vessels enter here and bring lymph in
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convex lymph side
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ateries, veins, nerves
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nodules
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structural unit of a lymph node; makes more efficient with these chambers
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lymphocytes
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immunity's main function, is produced in lymph nodes and are phagocytic for cleaning debris, waste, etc...
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a swollen node means you have an overproduction of
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lymphocytes or peyer's pathches in intestine
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____ travels through lymph nodes
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cancer
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lymph function
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clean plasma to take back to the heart
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there is no direct connection between the heart and the
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lymphatic system
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we move lymph through:
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valves
breathing hydrostatic pressure skeletal muscle *same as veins |
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thymus gland
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attaches to the top of heart, composed of lobules
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thymus gland info:
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starts out as lyphatic tissue, is active through puberty and young adolescence, turns to adipose tissue in the elderly and elastic b/c it is no longer needed
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lobules
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compartments in the thymus held together by c.t; lymphocytes located here
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thymocytes
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are lymphocytes that are in the thymus gland and are INACTIVE
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when thymocytes gain an active function they are called
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t-cells ,t-lymphocytes
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thymosin
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is required to changed thymocytes to t-cells as well as promoting there maturity.
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if you have an inefficient amount of thymosin you wont have any
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t- cells
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we gain most immunity through t-cells during
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puberty
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spleen
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the biggest lymphatic organ, just lateral to the stomach
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lobules
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compartments of spleen
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spleen is a
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non vital organ you can live without
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non vital define:
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you can live without
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fuctions of spleen
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filters blood
stores blood |
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liver can taker over functions of the
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spleen because it is a non-vital organ.
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white pulp
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are masses of lymphocytes, inside the lobules, cleans and filters blood taking out what we dont need or want
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red pulp
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blood or RBCs
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when lymphocytes are in the spleen they are
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phagocytic
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what are 3 phagocytic things in the lymphatic system
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liver, spleen, lymphocytes
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immunity
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our body's response to infection or inflammation
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infection
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the presence and multiplication of disease causing agents.
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pathogens
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living disease causings agents
-bacteria -viruses -protozoans -fungi |
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what are the types of pathogens
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-bacteria
-viruses -protozoans -fungi |
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allergens
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list could be living or non
-dust -cat dander -house hold cleaners -pollen(living) |
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types of allergens
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-dust
-cat dander -house hold cleaners -pollen (living) |
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anything that lymphocytes respond to, as far as an immune response, that come in the body is an ____
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antigen
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antigens are
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non-living and living
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self substance
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what your body produces is self substance
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non self substance
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come from someone else; is produced else where
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most ___ are good and we need them
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bacteria
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fetus is a
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non self substance
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selective supression immune system
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is when you have a spontaneous abortion t-cells b/c body rejects sperm
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non specific immunity
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1.species resistance
2.mechanical barrier 3.enzymtic action 4.interferon 5.inflammation 6.phagocytosis |
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two types of immunity
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specific immunity
non specific immunity |
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species resistance
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we have a blanket immunity to disease that other species get so we dont get
1.parvo, hiv |
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mechanical barrier
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skin, we have it, maintains the homeostasis of the body
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enzymatic action
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have enzymes in our fluid even tears (lysozyme) keep bacterial levels down
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interferon
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hormone-like peptide, used to treat cancer (tumors), responds to virus and stops the spread
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inflammation
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inflammatory response, WBC come to site due to bruise open cut etc., macrophages, trying to localize it
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phagocytosis
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monocytes, neutrophils are phagocytic, mono eat big stuff
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specific immunity
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pathogens
toxins poisonous substances |
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antigens
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anything that which a lymphocyte displays an immune response
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antigens types
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pathogens
allergens |
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pathogens
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disease causing; living
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allergens
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can be living or non living and cause allergic reactions
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haptens
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small antigens; come into the body on other big antigens; can be like dust or chemicals in the air
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stem cells
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undifferentiated lymphocytes; do not have a purpose yet
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50% of the cells come from the RBC and go to the
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thymus gland(to differentiate) then thymosin changes it to T-cells; enters blood for second time or can circulate in blood for 2nd time about 70-80 do this and the rest go to the sites of lymph nodes and sites of spleen
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other 50% of the cells come from the RBC and go to the
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fetal liver to be processed; they become b-lymphocytes (B-cells) which is bone marrow derived; two ways for entry into the blood: about 20-30% circulate lymphocyte and others settle in lymphatic organs and lobes of the spleen.
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lymphokines
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chemical substance that T-cells produce to help the cells fight of antigens
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b- means
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bone marrow derived
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t- means
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thymus derived
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antibodies
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are proteins, are produced and secreted by b-cells`
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b-cells produce what
t-cells produce what |
antibodies
lymphokines |
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t-cells info
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require the presense of another kind of cell (accessory cell) before they can be activated
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t-cell can be activated by (accessory cells)
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macrophages, b-cells
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b-cells info
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can be activated when encountering an antigen whose molecular shape fits the shape of the b-cells anitigen receptors
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Antibodies info
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are produced and secreted by the b-cells; are soluble globular proteins called immunoglobulins (aka antibody)
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primary immune response
secondary immunse response |
first encounter a lymhocyte has with the antigen, everything after is secondary
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immunoglobulins
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secreted by b-cells; are soluble globular proteins; aka antibodies
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secondary immune response
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memory cells; remember and the t-cells encounter and take care of it
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antigens
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B-cells:
globular proteins (immunoglobulins) attack antigens directly activate enzymes stimulate local changes to prevent spread of antigens |
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specific immunity
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three ways to gain
-naturally aquired -artiffically aquired active immunity -artificially aquired passive immunity |
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naturally aquired active immunity
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obtained by disease; antigen and immunity are then naturally acquired which contribute to long term immunity.
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artificially aquired active immunity
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vaccine; are long term
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artificially aquired passive immunity
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gamma globulin injection; ready made antibodies are short term immunity
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allergens non-living, living or
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immediate-show up now
delayed- reaction later |
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specialized group of t-cells, supress reaction
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supressor cells
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selective suppressive immunity
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allow you to carry a fetus and sperm; some people dont have this immunity and have spontaneous abortions
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immunosuppressive drugs
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non self substance; we use these drugs to help the body suppress our immune systems
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lacteals
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specialized lymphatic capillaries located in the villi of the small intestine
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lacteals functions
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absorb and transport lipids/fats from the digestive system
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tissue fluid that enters the lymphatic cavity is known as what
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lymph
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lymph glands are also known as
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lymph nodes
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what is the largest lymphatic organ
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spleen
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tissue fluid that has entered a lymphatic capillary is called
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lymph
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where are t-cells produced
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thymus gland
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disease causing agents
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pathogens
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types of non-specific immunity
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species resistance
mechanical barriers inflammation interferon phagocytosis |
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a group of hormone like peptides produced by lymphocytes and fibroblasts that inhibit the proliferation of viruses, stimulate phagocytoysis and enhance cell resistance to infections and tumor growth
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interferons
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the resistance of particular foreign agents, pathogens and or their toxins
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specific immunity
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an artificially aqured immunity
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vaccine
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reactions can either be immediate or delayed
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allergic
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immuno-suppressants
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are given to people who are given organ transplants
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lymph from the lower regions of the body, the left arm the left side of the head and neck enters the ___ duct of the lymphatic system that begins in the abdomen
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thoracic
abdomen=thoracic cavity |
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the right lymphatic duct empties into
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right subclavin vein
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movement of lymph is controlled by
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skeletal muscle activity
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the structural units of lymph nodes are called
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nodules
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lymph nodes contain large numbers of cells called
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lymphocytes
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large numbers of ___ are responsible for the red pulp in the spleen
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RBCs
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the body's defense mechanisms against disease causing agents
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immunity
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One of the primary functions of the lymph nodes is to produce these cells
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lymphocytes; differentiate into T-cells and B-cells
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Lymphatic vessels
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Lymphatic vessels contain valves.
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The lymphatic system is closely associated with the cardiovascular system.
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They are not the same...
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Lymphatic vessels unite with what vessels
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Lymphatic vessels unite with lymphatic trunks
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The right lymphatic duct empties into
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right subclavian vein.
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peyer's patches are
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organized lymphoid nodules, usually found in the lowest portion of the small intestine (ileum), Because the lumen of the gastrointestinal tract is exposed to the external environment, much of it is populated with potentially pathogenic microorganisms. Peyer's patches thus establish their importance in the immune surveillance of the intestinal lumen and in facilitating the generation of the immune response within the mucosa.
Pathogenic microorganisms and other antigens entering the intestinal tract encounter macrophages, dendritic cells, B-lymphocytes, and T-lymphocytes found in Peyer's patches and other Mucosa Associated Lymphatic Tissue (MALT). |
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Tissue fluid originates
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blood plasma
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The spleen is located in front of the aortic arch.
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False: lateral to the stomach
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T-cells
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may interact directly with foreign cells
can synthesize and secrete lymphokines may secrete toxic substances that are lethal to their antigen-binding cells provide cell mediated immunity for the body |
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B-cells act directly against antigens by producing and secreting globular proteins or immunoglobulins called
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antibodies
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the members of each variety of lymphocytes as a group
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Clone
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Antibodies
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react to antigens by attacking them directly
activate a set of enzymes that attack antigens stimulate changes in local areas that help prevent the spread of antigens |
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Three possible pathogens
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viruses
bacteria fungi |
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2 primary substances returned to the bloodstream by the lymphatic system:
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plasma
nutrients |