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135 Cards in this Set

  • Front
  • Back
functions of the lymphatic system:
two major functions
-immunity
-to help maintain blood volume
lacteals
located in the alveoli of the small intestine; specialized lymphatic capillaries found in the small intestine; pick up absorbed fats for transport.
most nutrients are absorbed in the blood except
lipids aka fats
lipids are taken care of where
in the liver
lyphatic system: first main function
to help maintain blood volume.
-when you have capillary beds some plasma leaks out you see some plasma gone due to :
- osmotic pressure changing
-hydrostic pressure changing if it happens arround tissue it is called edema.
when plasma escapes
you get swelling called edema.
interstintial fluid
is composed of plasma, plasma electrolytes, plasma gases, is outside the blood stream and if it keeps accumulating you will get edema.
lyphatic capillaries
are the smallest structures in the lymphatic system, located in the interstitial fluid, and are there to pick up excess interstitial fluid so you dont get edema.
lymphatic capillaries are made of
simple squamous epithelial cells
so the interstitial fluid is picked up by ___ and once it is picked up the name is now called ____
lyphatic capillaries, lymph
capillaries come together to larger things called
lyphatic vessels
lymphatic vessels
are similiar to veins in the circulaory system, have tunics and valves, three layers , pass through several lymph nodes
what filters lymph?
lymph nodes
lymphatic vessels are the only thing that can go through
lymph nodes
several lymphatic vessels may come togther to form larger vessels called
lymphatic trunks and are named after the section of the body that they drain (abdomen).
In the lymphatic system several trunks come back togther to form two main lymphatic ducts (two large structures)
-right thoracic duct
-thoracic duct
thoracic duct
longest and largest of two ducts; originates in the abdominal pelvic and runs into the chest cavity and brings the fluid from the legs up (lymph or plasma) returns to circulatory system and joins the left subclavian vein and empties here, (by left jugular vein) then dumped into the RA (oxygen poor side)
right thoracic duct
Right side version of the thoracic duct; starts and stops in the thoracic cavity and drains the head and neck; returns filtered plasma into the right subclavian vein.
left subclavian vein
is where the thoracic cavity empties, (by left jugualr vein), then dumped into the RA (oxygen poor side)
what are the functions of the ducts
to return filtered plamsa to the HEART
lymph nodes info:
has a convex surface and a concave surface, has one opening into the hilum, is living tissue which needs blood supply
hilum
opening into the lymph node on concave side (all blood supply enters here; arteries, veins, nerves...)
concave lymph side
afferent lymph vessels enter here and bring lymph in
convex lymph side
ateries, veins, nerves
nodules
structural unit of a lymph node; makes more efficient with these chambers
lymphocytes
immunity's main function, is produced in lymph nodes and are phagocytic for cleaning debris, waste, etc...
a swollen node means you have an overproduction of
lymphocytes or peyer's pathches in intestine
____ travels through lymph nodes
cancer
lymph function
clean plasma to take back to the heart
there is no direct connection between the heart and the
lymphatic system
we move lymph through:
valves
breathing
hydrostatic pressure
skeletal muscle
*same as veins
thymus gland
attaches to the top of heart, composed of lobules
thymus gland info:
starts out as lyphatic tissue, is active through puberty and young adolescence, turns to adipose tissue in the elderly and elastic b/c it is no longer needed
lobules
compartments in the thymus held together by c.t; lymphocytes located here
thymocytes
are lymphocytes that are in the thymus gland and are INACTIVE
when thymocytes gain an active function they are called
t-cells ,t-lymphocytes
thymosin
is required to changed thymocytes to t-cells as well as promoting there maturity.
if you have an inefficient amount of thymosin you wont have any
t- cells
we gain most immunity through t-cells during
puberty
spleen
the biggest lymphatic organ, just lateral to the stomach
lobules
compartments of spleen
spleen is a
non vital organ you can live without
non vital define:
you can live without
fuctions of spleen
filters blood
stores blood
liver can taker over functions of the
spleen because it is a non-vital organ.
white pulp
are masses of lymphocytes, inside the lobules, cleans and filters blood taking out what we dont need or want
red pulp
blood or RBCs
when lymphocytes are in the spleen they are
phagocytic
what are 3 phagocytic things in the lymphatic system
liver, spleen, lymphocytes
immunity
our body's response to infection or inflammation
infection
the presence and multiplication of disease causing agents.
pathogens
living disease causings agents
-bacteria
-viruses
-protozoans
-fungi
what are the types of pathogens
-bacteria
-viruses
-protozoans
-fungi
allergens
list could be living or non
-dust
-cat dander
-house hold cleaners
-pollen(living)
types of allergens
-dust
-cat dander
-house hold cleaners
-pollen (living)
anything that lymphocytes respond to, as far as an immune response, that come in the body is an ____
antigen
antigens are
non-living and living
self substance
what your body produces is self substance
non self substance
come from someone else; is produced else where
most ___ are good and we need them
bacteria
fetus is a
non self substance
selective supression immune system
is when you have a spontaneous abortion t-cells b/c body rejects sperm
non specific immunity
1.species resistance
2.mechanical barrier
3.enzymtic action
4.interferon
5.inflammation
6.phagocytosis
two types of immunity
specific immunity
non specific immunity
species resistance
we have a blanket immunity to disease that other species get so we dont get
1.parvo, hiv
mechanical barrier
skin, we have it, maintains the homeostasis of the body
enzymatic action
have enzymes in our fluid even tears (lysozyme) keep bacterial levels down
interferon
hormone-like peptide, used to treat cancer (tumors), responds to virus and stops the spread
inflammation
inflammatory response, WBC come to site due to bruise open cut etc., macrophages, trying to localize it
phagocytosis
monocytes, neutrophils are phagocytic, mono eat big stuff
specific immunity
pathogens
toxins poisonous substances
antigens
anything that which a lymphocyte displays an immune response
antigens types
pathogens
allergens
pathogens
disease causing; living
allergens
can be living or non living and cause allergic reactions
haptens
small antigens; come into the body on other big antigens; can be like dust or chemicals in the air
stem cells
undifferentiated lymphocytes; do not have a purpose yet
50% of the cells come from the RBC and go to the
thymus gland(to differentiate) then thymosin changes it to T-cells; enters blood for second time or can circulate in blood for 2nd time about 70-80 do this and the rest go to the sites of lymph nodes and sites of spleen
other 50% of the cells come from the RBC and go to the
fetal liver to be processed; they become b-lymphocytes (B-cells) which is bone marrow derived; two ways for entry into the blood: about 20-30% circulate lymphocyte and others settle in lymphatic organs and lobes of the spleen.
lymphokines
chemical substance that T-cells produce to help the cells fight of antigens
b- means
bone marrow derived
t- means
thymus derived
antibodies
are proteins, are produced and secreted by b-cells`
b-cells produce what
t-cells produce what
antibodies
lymphokines
t-cells info
require the presense of another kind of cell (accessory cell) before they can be activated
t-cell can be activated by (accessory cells)
macrophages, b-cells
b-cells info
can be activated when encountering an antigen whose molecular shape fits the shape of the b-cells anitigen receptors
Antibodies info
are produced and secreted by the b-cells; are soluble globular proteins called immunoglobulins (aka antibody)
primary immune response
secondary immunse response
first encounter a lymhocyte has with the antigen, everything after is secondary
immunoglobulins
secreted by b-cells; are soluble globular proteins; aka antibodies
secondary immune response
memory cells; remember and the t-cells encounter and take care of it
antigens
B-cells:
globular proteins (immunoglobulins)
attack antigens directly
activate enzymes
stimulate local changes to prevent spread of antigens
specific immunity
three ways to gain
-naturally aquired
-artiffically aquired active immunity
-artificially aquired passive immunity
naturally aquired active immunity
obtained by disease; antigen and immunity are then naturally acquired which contribute to long term immunity.
artificially aquired active immunity
vaccine; are long term
artificially aquired passive immunity
gamma globulin injection; ready made antibodies are short term immunity
allergens non-living, living or
immediate-show up now
delayed- reaction later
specialized group of t-cells, supress reaction
supressor cells
selective suppressive immunity
allow you to carry a fetus and sperm; some people dont have this immunity and have spontaneous abortions
immunosuppressive drugs
non self substance; we use these drugs to help the body suppress our immune systems
lacteals
specialized lymphatic capillaries located in the villi of the small intestine
lacteals functions
absorb and transport lipids/fats from the digestive system
tissue fluid that enters the lymphatic cavity is known as what
lymph
lymph glands are also known as
lymph nodes
what is the largest lymphatic organ
spleen
tissue fluid that has entered a lymphatic capillary is called
lymph
where are t-cells produced
thymus gland
disease causing agents
pathogens
types of non-specific immunity
species resistance
mechanical barriers
inflammation
interferon
phagocytosis
a group of hormone like peptides produced by lymphocytes and fibroblasts that inhibit the proliferation of viruses, stimulate phagocytoysis and enhance cell resistance to infections and tumor growth
interferons
the resistance of particular foreign agents, pathogens and or their toxins
specific immunity
an artificially aqured immunity
vaccine
reactions can either be immediate or delayed
allergic
immuno-suppressants
are given to people who are given organ transplants
lymph from the lower regions of the body, the left arm the left side of the head and neck enters the ___ duct of the lymphatic system that begins in the abdomen
thoracic
abdomen=thoracic cavity
the right lymphatic duct empties into
right subclavin vein
movement of lymph is controlled by
skeletal muscle activity
the structural units of lymph nodes are called
nodules
lymph nodes contain large numbers of cells called
lymphocytes
large numbers of ___ are responsible for the red pulp in the spleen
RBCs
the body's defense mechanisms against disease causing agents
immunity
One of the primary functions of the lymph nodes is to produce these cells
lymphocytes; differentiate into T-cells and B-cells
Lymphatic vessels
Lymphatic vessels contain valves.
The lymphatic system is closely associated with the cardiovascular system.
They are not the same...
Lymphatic vessels unite with what vessels
Lymphatic vessels unite with lymphatic trunks
The right lymphatic duct empties into
right subclavian vein.
peyer's patches are
organized lymphoid nodules, usually found in the lowest portion of the small intestine (ileum), Because the lumen of the gastrointestinal tract is exposed to the external environment, much of it is populated with potentially pathogenic microorganisms. Peyer's patches thus establish their importance in the immune surveillance of the intestinal lumen and in facilitating the generation of the immune response within the mucosa.
Pathogenic microorganisms and other antigens entering the intestinal tract encounter macrophages, dendritic cells, B-lymphocytes, and T-lymphocytes found in Peyer's patches and other Mucosa Associated Lymphatic Tissue (MALT).
Tissue fluid originates
blood plasma
The spleen is located in front of the aortic arch.
False: lateral to the stomach
T-cells
may interact directly with foreign cells
can synthesize and secrete lymphokines
may secrete toxic substances that are lethal to their antigen-binding cells
provide cell mediated immunity for the body
B-cells act directly against antigens by producing and secreting globular proteins or immunoglobulins called
antibodies
the members of each variety of lymphocytes as a group
Clone
Antibodies
react to antigens by attacking them directly
activate a set of enzymes that attack antigens
stimulate changes in local areas that help prevent the spread of antigens
Three possible pathogens
viruses
bacteria
fungi
2 primary substances returned to the bloodstream by the lymphatic system:
plasma
nutrients