Ap2, Chap 22, Lymphatic System & Immunity

Front 1

The primary function of the lymphatic system is the ___ ___ & ___ of lymphocytes.

Back 1

production, maintenance, and distribution

Front 2

System that provides a defense against infections and other environmental hazards.

Back 2

lymphatic system

Front 3

Small lymphatic vessels
contain layers like veins, and the larger lymphatic vessels contain ___.

Back 3

valves

Front 4

___ cells account for 10-15 percent of circulating lymphocytes

Back 4

B

Front 5

When stimulated, B cells can differentiate into ___ cells

Back 5

plasma

Front 6

plasma cells are responsible for the production and secretion of _____ .

Back 6

antibodies

Front 7

____ cells are soluble proteins also known as immunoglobulins.

Back 7

plasma

Front 8

___ cells are responsible for
Antibody-mediated immunity.

Back 8

B

Front 9

Antibody-mediated immunity, a.k.a. as humoral ("liquid") immunity because antibodies occur in ___ ___ .

Back 9

body fluids

Front 10

___ cells and ___ cells mature in bone marrow.

Back 10

B, NK

Front 11

T cells mature in the ____ .

Back 11

thymus

Front 12

What does MALT stand for?

Back 12

MALT (mucosa-associated lymphoid tissue)

Front 13

What are Peyer's patches?

Back 13

Clusters of lymphoid nodules deep to the epithelial lining of the intestine

Front 14

Large nodules in the walls of the pharynx

Back 14

Tonsils

Front 15

What is lymphadenopathy?

Back 15

Chronic or excessive enlargement of lymph nodes

Front 16

What can cause lymphadenopathy?

Back 16

bacterial or viral infections, endocrine disorders, or cancer

Front 17

The ___ ___ contains the largest collection of lymphoid tissue in the body.

Back 17

adult spleen

Front 18

The cellular components of the spleen form ___.

Back 18

pulp

Front 19

Removal of abnormal blood cells,Storage of iron &
initiation of the specific immune response are functions of what organ?

Back 19

Spleen

Front 20

Perform janitorial and police services in peripheral tissues

Back 20

Phagocytes

Front 21

Cells that remove cellular debris and responding to invasion by foreign compounds or pathogens

Back 21

Phagocytes

Front 22

Phagocytes represent the "first line" of cellular defense against ___ invasions

Back 22

pathogenic

Front 23

Microphages are the ___ & ___ that normally circulate in the blood

Back 23

neutrophils and eosinophils

Front 24

Both free & fixed macrophages are derived from the ___ of the blood.

Back 24

monocytes

Front 25

"Fixed" macrophages are ___ & ___

Back 25

Microglia and Kupffer

Front 26

"Free" macrophages are ___

Back 26

Alveolar

Front 27

(NK) cells: What does NK stand for?

Back 27

Natural killer

Front 28

Responsible for recognizing and destroying abnormal cells when they appear in peripheral tissues

Back 28

(NK) cells

Front 29

The constant monitoring of normal tissues by NK cells is called ___ ___ .

Back 29

immunological surveillance.

Front 30

What non-specific pathway is the most rapid and effective?

Back 30

The Classical Pathway

Front 31

The "classical pathway" begins when a complement protein, ___, binds to an antibody molecule.

Back 31

C1

Front 32

The "pyrogen" released by active macrophages is a ___ called endoge-nous pyrogen, or interleukin-1

Back 32

cytokine

Front 33

responsible for cell-mediated immunity, our defense against abn. cells & pathogens inside cells.

Back 33

T cells

Front 34

Provide antibody-mediated immunity (humoral), our defense against antigens and pathogens in body fluids.

Back 34

B cells

Front 35

Immunity present at birth and has no relationship to previous exposure to the antigen involved.

Back 35

Innate immunity

Front 36

a result of natural exposure to an antigen in the environment (naturally acquired immunity) or from deliberate exposure to an antigen eg. Vaccine

Back 36

Active immunity

Front 37

Active immunity as a result of natural exposure to an antigen in the environment

Back 37

naturally acquired immunity

Front 38

Active immunity acquired from deliberate exposure to an antigen eg. Vaccine.

Back 38

induced active immunity

Front 39

protecting her baby against infections during gestation.

Back 39

Natural passive immunity

Front 40

Immunity resulting from a mother's antibodies through breast milk.

Back 40

Natural passive immunity

Front 41

Immunity:
Activated by and responds to a specific antigen

Back 41

Specificity

Front 42

Immunity:
Is ready to confront any antigen at any time

Back 42

Versatility

Front 43

Immunity:
“Remembers” any antigen it has encountered

Back 43

Memory

Front 44

Immunity:
Responds to foreign substances but ignores normal tissues

Back 44

Tolerance

Front 45

Inhibits T cell and B cell activities and moderate immune response.

Back 45

Suppressor T cells (TS)

Front 46

Responsible for resistance against many viruses, bacteria, and bacteria toxins.

Back 46

IgG

Front 47

These antibodies can cross the placenta

Back 47

IgG

Front 48

During embryological development, maternal ___ provides maternal immunity to the fetus.

Back 48

IgG

Front 49

Attaches as an individual molecule to the exposed surfaces of Basophils and mast cells.

Back 49

IgE

Front 50

Is an individual molecule on the surfaces of B cells, where it can bind antigens in the extracellular fluid

Back 50

IgD

Front 51

It is the first antibody secreted after an antigen arrives.

Back 51

IgM

Front 52

Circulates as a five antibody starburst. It binds first follow by IgG.

Back 52

IgM

Front 53

Is found primarily in glandular secretions such as mucus, tears, and saliva.

Back 53

IgA

Front 54

What are the two types of antibodies involved in the primary response?

Back 54

IgM and ????

Front 55

What is an allergy?

Back 55

Inappropriate or excessive immune response to allergens