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55 Cards in this Set

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  • Back
The primary function of the lymphatic system is the ___ ___ & ___ of lymphocytes.
production, maintenance, and distribution
System that provides a defense against infections and other environmental hazards.
lymphatic system
Small lymphatic vessels
contain layers like veins, and the larger lymphatic vessels contain ___.
valves
___ cells account for 10-15 percent of circulating lymphocytes
B
When stimulated, B cells can differentiate into ___ cells
plasma
plasma cells are responsible for the production and secretion of _____ .
antibodies
____ cells are soluble proteins also known as immunoglobulins.
plasma
___ cells are responsible for
Antibody-mediated immunity.
B
Antibody-mediated immunity, a.k.a. as humoral ("liquid") immunity because antibodies occur in ___ ___ .
body fluids
___ cells and ___ cells mature in bone marrow.
B, NK
T cells mature in the ____ .
thymus
What does MALT stand for?
MALT (mucosa-associated lymphoid tissue)
What are Peyer's patches?
Clusters of lymphoid nodules deep to the epithelial lining of the intestine
Large nodules in the walls of the pharynx
Tonsils
What is lymphadenopathy?
Chronic or excessive enlargement of lymph nodes
What can cause lymphadenopathy?
bacterial or viral infections, endocrine disorders, or cancer
The ___ ___ contains the largest collection of lymphoid tissue in the body.
adult spleen
The cellular components of the spleen form ___.
pulp
Removal of abnormal blood cells,Storage of iron &
initiation of the specific immune response are functions of what organ?
Spleen
Perform janitorial and police services in peripheral tissues
Phagocytes
Cells that remove cellular debris and responding to invasion by foreign compounds or pathogens
Phagocytes
Phagocytes represent the "first line" of cellular defense against ___ invasions
pathogenic
Microphages are the ___ & ___ that normally circulate in the blood
neutrophils and eosinophils
Both free & fixed macrophages are derived from the ___ of the blood.
monocytes
"Fixed" macrophages are ___ & ___
Microglia and Kupffer
"Free" macrophages are ___
Alveolar
(NK) cells: What does NK stand for?
Natural killer
Responsible for recognizing and destroying abnormal cells when they appear in peripheral tissues
(NK) cells
The constant monitoring of normal tissues by NK cells is called ___ ___ .
immunological surveillance.
What non-specific pathway is the most rapid and effective?
The Classical Pathway
The "classical pathway" begins when a complement protein, ___, binds to an antibody molecule.
C1
The "pyrogen" released by active macrophages is a ___ called endoge-nous pyrogen, or interleukin-1
cytokine
responsible for cell-mediated immunity, our defense against abn. cells & pathogens inside cells.
T cells
Provide antibody-mediated immunity (humoral), our defense against antigens and pathogens in body fluids.
B cells
Immunity present at birth and has no relationship to previous exposure to the antigen involved.
Innate immunity
a result of natural exposure to an antigen in the environment (naturally acquired immunity) or from deliberate exposure to an antigen eg. Vaccine
Active immunity
Active immunity as a result of natural exposure to an antigen in the environment
naturally acquired immunity
Active immunity acquired from deliberate exposure to an antigen eg. Vaccine.
induced active immunity
protecting her baby against infections during gestation.
Natural passive immunity
Immunity resulting from a mother's antibodies through breast milk.
Natural passive immunity
Immunity:
Activated by and responds to a specific antigen
Specificity
Immunity:
Is ready to confront any antigen at any time
Versatility
Immunity:
“Remembers” any antigen it has encountered
Memory
Immunity:
Responds to foreign substances but ignores normal tissues
Tolerance
Inhibits T cell and B cell activities and moderate immune response.
Suppressor T cells (TS)
Responsible for resistance against many viruses, bacteria, and bacteria toxins.
IgG
These antibodies can cross the placenta
IgG
During embryological development, maternal ___ provides maternal immunity to the fetus.
IgG
Attaches as an individual molecule to the exposed surfaces of Basophils and mast cells.
IgE
Is an individual molecule on the surfaces of B cells, where it can bind antigens in the extracellular fluid
IgD
It is the first antibody secreted after an antigen arrives.
IgM
Circulates as a five antibody starburst. It binds first follow by IgG.
IgM
Is found primarily in glandular secretions such as mucus, tears, and saliva.
IgA
What are the two types of antibodies involved in the primary response?
IgM and ????
What is an allergy?
Inappropriate or excessive immune response to allergens