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152 Cards in this Set

  • Front
  • Back
What are the two enlargements of the spinal cord and where are they found?
cervical (c4-t1)
lumbar (t9-t12)
What are the general research categories of anatomy?
gross (macro)
embryology (developmental)
microscopic (histology)
surface (topographical)
What percentage of bone matrix is water?
15%
4 types of tissues?
epithelial
muscle
nervous
connective
What are the two subdivisions of the nervous system
CNS, PNS
Where is the conus medullaris found?
L1-L2
What are the 6 levels of structural organisation?
chemicals
cells
tissues
organs
systems
organism
What percentage of bone matrix is collagen?
30%
4 possible physical states of tissues?
solid, semisolid, liquid
What are the main components of the PNS?
Nerves, ganglia, sensory receptor, enteric plexus
what is the filum terminale?
a fibrous tissue that anchors the spinal cord to the coccyx
What are the 11 systems of the human body?
skeletal
muscular
intergumentary
nervous
urinary
digestive
lymphatic
respiratory
cardiovascular
reproductive
endocrine
What percentage of bone matrix is crystallized mineral salts?
55%
Characteristics of epithelial tissues (ECM, nerve supply, blood supply)
small amount of ECM
nervous
no direct blood supply
What are the subdivisions of the PNS?
Somatic, Autonomic, Enteric
What is the collection of roots which extend inferiorly from the conus medullaris?
the cauda equina
What are the four cavities of the body with subcavities?
Cranial
Vertebral
Thoracic (pleural, pericardium, mediastinum)
Abdominopelvic (abdominal, pelvic)
Name the three main components of bone matrix
collagen, crystallized mineral salts, water
Name the shapes of epithelial cells
cuboidal, squamous, columnar, transitional
What are the subdivisions of the autonomic motor PNS?
Sympathetic, parasympathetic
What are the meninges and what are the spaces around them?
epidural
dura mater
subdural
arachnoid
subarachnoid
pia mater
What are the two ways to subdivide the abdominopelvic cavity?
quadrants (left and right, upper and lower)
9 regions (left and right hypochondriac, epigastric, left and right lumbar, umbilical, left and right inguinal, hypogastric)
What are the main components of the crystallized mineral salts in bone matrix?
calcium phosphate, calcium hydroxide and calcium carbonate. Also in the bone matrix are Mg, F, S04 and K
Classify epithelial cells by layer type
simple
stratified
pseudostratified
What are the functions of the nervous system?
sensory, integrative, motor
What is found in the epidural space?
fat, connective tissue
Name the four types of bone cells
Osteoclasts, osteoblasts, osteocytes, osteogenic cells
Classify epithelial cells by function
barrier (covering or lining)
glandular (secretion and absorption)
What are the structural classifications of neurons?
(multi, uni, bi) polar
What is found in the subdural space?
interstitial fluid
Where are osteogenic cells found?
inner periosteum, endosteum and haversian canals
Where are cuboidal epithelial cells found?
ovaries, kidneys
What are the functions of astrocytes?
Structural support
blood-brain barrier
secrete chemicals in embryo
homeostasis of neuronal chemical environment of neurons
role in learning and memory by influencing the formation of neural synapses
What is found in the subarachnoid space?
CSF
What is the function of osteocytes?
Maintain metabolism - exchange of nutrients and wastes with blood
Where are squamous epithelial cells found?
lips, cervix
What are the two types of astrocytes and where are they found?
Fibrous - white matter
protoplasmic - grey matter
Which meningeal layer contains blood vessels?
pia mater
When does ossification start in the human body?
Around 6 weeks
Where are columnar epithelial cells found?
respiratory system, digestive tract, female reproductive system
What is the function of oligodendrocytes?
Produce and maintain myelin sheath
Where is CSF made?
choroid plexus (ependymal cells)
What are the two types of bone development?
Intramembranous and Endochondral (more common)
Where are transitional epithelial cells found?
urinary bladder
What is the function of microglia?
phagocytosis of celllular debris
How many pairs of spinal nerves are there in the human body? How many in each section?
31
8, 12, 5, 5, 1
What are the four stages of intermembranous ossification?
Development of ossification centre
calcification
formation of trabeculate
development of periosteum
Where are simple epithelial cells found?
kidneys, alveoli, blood vessels
Which type of neuron has many dendrites?
Multipolar
What do dorsal roots carry?
sensory APs
What are the six stages of endochondral ossification?
development of cartilage model
growth of cartilage model
development of primary ossification centre
development of medullary cavity
development of secondary ossification centre
formation of articular cartilage and epiphyseal plate
What is the main function of cuboidal epithelial cells?
secretion and absorption, may have microvilli
Which neurons are fused together to form a long chain?
Unipolar
What do ventral roots carry?
motor APs
Name the various components of osteons
central (haversian) canal, lamellae, lacunae, osteocytes, canaliculi. Blood vessels, nerves and lymphatic vessels penetrate though perforating or volkmann's canals.
What is the main function of squamous epithelial cells?
rapid diffusion
Where are bipolar neurons found?
The eye, inner ear, and olfactory area
Within the spinal cord, columns have a common _____ and a common _______
origin and destination
Flat bones, short bones and irregular bones are mostly formed of which type of bone?
spongy
What is the main function of columnar epithelial cells?
protect tissues, may have cilia, microvilli
Discuss the structure and function of ependymal cells
Shape - cuboidal to columnar
Single layer
have microvilli and cilia
produce and monitor CSF
What does grey matter consist of?
dendrites, cell bodies, axons and neuroglia
How many bones in the axial and appendicular portion of the body?
80- axial
126- appendicular
Where are stratified epithelial cells found?
dorsum of tongue, hard palate, esophagus
What purpose do Schwann cells have?
produce myelin sheath, neurolemma
Where is the central canal?
Centrally located within the grey matter
Name a couple of functions of sesamoid bones
protect tendon, increase mechanical effect of tendon
Where are pseudostratified epithelial cells found?
trachea, respiratory system
What do satellite cells do and where are they found?
provide support and regulate the exchange of materials in the PNS
What neurons do the posterior grey horns contain?
sensory, interneurons
Which hormones stimulate or regulate growth and from which gland do they originate?
hGH - pituitary
t3, t4, calcitonin - thyroid
PTH - parathyroid
testosterone, estrogen - testes, ovaries, adrenal glands
What is the main function of simple epithelial cells?
diffusion, secretion, absorption, osmosis, filtration
What two types of synapses are found within the nervous system?
Electrical (gap junction) and chemical
What neurons do the anterior grey horns contain?
motor
What protein promotes growth in childhood? What does this protein do? Where is it produced?
Insulin-like Growth Factors (IGFs)
promotes osteoblast function, cell division and enhances the synthesis of new proteins
produced in response to hGH in the liver and bone tissues
Does connective tissue have nerve and blood supply?
yes, except for cartilage
Where are gap junctions found?
heart, smooth muscle, brain
What neurons do the lateral grey horns contain?
autonomic regulation
What hormones promote bone growth in childhood?
Insulin (promotes protein synthesis)
T3 and T4
Name the functions of connective tissue?
storage of energy
protection of organs
structural framework for the body
Name two advantages of gap junctions
faster communication, synchronized
True or false: thoracic spinal nerves pass over the vertebral body?
false
What are the two criteria for classifying joints?
1. presence of space between joints
2. the type of connective tissue that holds the bones together
What are the main components of connective tissue?
ECM, fibres, cells
Describe the mechanism for chemical interneuronal transmission
neurotransmitter, which is stored in synaptic bulbs and varicosities, is released and crosses the synaptic cleft to the postsynaptic dendrite
What are the groupings within a nerve?
neuron
endoneurium
fascicle
perineurium
epineurium
Name the joint types
Fibrous, cartilaginous and synovial
What are the two main components of the ECM?
ground substance, fibres
What are the two types of axonal transport and what direction does each travel in?
Slow - body to axonal terminals (anteriograde)
fast - both directions (retrograde and anteriograde)
What do the three nerve branches serve?
anterior - muscles of upper and lower limbs, skin of lateral and anterior trunk
posterior - deep muscles and skin of posterior trunk
meningeal - reenters vertebral cavity through intervertebral foramen
What are the three types of fibrous joints? Give an example of each
Sutures - skull joints
syndesmones - gomphosis
interosseus membranes - between ulna and radius
what are the possible states of ground substance?
fluid, semifluid, gelatinous, calcified
What is characteristic of perkinje neurons and where are they found?
Many dendritic processes
cerebellum
What are the five spinal plexuses and what do they serve?
Cervical (c1-4) - skin and muscles of the head-chest (contains phrenic nerve)
Brachial (c4-t1) - upper limbs and shoulders
Lumbar (L1-4) - anterior lateral abdominal wall, external genital, part of lower limbs
Sacral - buttocks, perineum, lower limbs
Coccygeal - skin of that region
Name the two types of cartilaginous joints and give an example of each.
Synchondroses (hyaline cartilage, no movement) - epiphyseal plates
Symphyses - pubic symphysis
What are the three fibre types?
collagen, elastic, reticular (fine mesh)
Where are pyramidal neurons found and why are they named as such?
cerebral cortex
shape
Where does the sciatic nerve originate?
L4-S3
What are the components of a synovial joint?
Articular cartilage (reduce friction, absorb shock), articular capsule (forms ligaments), synovial membrane
What embryonic cells give rise to connective tissues?
mesenchymal cells
What are the factors for the speed of transmission in an axon?
temperature
diameter of axon
myelination
What does the sciatic nerve branch into?
tibial and common fibular nerves, send branches to hamstring muscles and abductor magnus
Name the classifications of synovial joints and give an example of each
Planar (navicular-lateral cuneiform), saddle (carpal-metacarpal of thumb), ball-and-socket (ishial-femoral), pivot (atlanto-axial), hinge (humero-ulnar), condyloid (radio-carpal)
What cells are commonly found in connective tissue?
fibroblasts, macrophages, plasma cells, mast cells, adipocytes
What are the steps for generation of APs?
Presence of concentration and voltage gradient
cell body reaches threshold
depolarization (Na channels)
repolarization (K channels)
hyperpolarization (Na/K pump)
rest period
What happens if the phrenic nerve is severed?
respiratory arrest
What are the determinants of joint range of motion
structure and shape of articulating surfaces
strength and tension of ligaments
arrangement and tension of muscles
contact of soft parts
hormones
amount of use
What are the 5 types of mature connective tissues?
loose, dense, cartilage, bone, liquid
Where is the phrenic nerve found?
cervical plexus
What are the types of fractures?
Colles (distal end of radius)
Pott (distal end of fibula)
comminuted
impacted
greenstick
open (compound)
stress
Areolar and adipose tissues fall into which category of connective tissues?
Loose
What is the largest lumbar nerve?
femoral
What are the three types of dense connective tissues? Give examples
regular (tendons), irregular (dermis), and elastic (lung tissue, arteries)
What is the largest nerve in the body?
sciatic
What are the three types of cartilage? Give an example of each
hyaline (ribs, nose, trachea)
fibrocartilage (intervertebral, meniscus of the knee)
elastic (epiglottis, external ear)
What is a plexus?
a network of nerves
What are the two types of bone?
spongy, compact
Name the liquid connective tissues
blood, lymph
What are the differences between connective and epithelial cells?
epithelial tightly packed
epithelial don't connect stuff together
epithelial has small amount of ECM
epithelial are organised into layers
epithelial are avascular
What are the three types of muscle tissues? Give an example of each
skeletal, biceps femoris
cardiac, heart
smooth, intestines, iris, urinary bladder
Which muscle types are striated?
Skeletal and cardiac
Which muscle types are mononucleated?
Cardiac and smooth
What attaches cardiac muscles to each other?
intercalcated discs
What word describes the shape of smooth muscle cells?
spindle
What are the four properties of muscle tissue?
extensibility
excitablility
elasticity
contractility
What two cell types are classified as nervous tissue?
nerves
glia
Receptors are sensitive to which stimuli?
heat/cold, light/dark, pressure
Name the parts of a neuron
soma, dendrites, axon, synaptic branches, synaptic bulbs,
Name the neuron types
afferent, efferent, interneurons
Name the types of neuroglia
astrocytes
oligodendrocytes
microglia
ependymal cells
What are the two types of glands?
endocrine and exocrine
Give an example of exocrine cells
goblet cells
Where do endocrine glands secrete their product[s]?
directly into interstitial fluid which diffuses into the bloodstream
Which organs have both types of glands?
pancreas, ovaries, testes
Name the major endocrine glands
pineal, pituitary, thyroid, thymus, adrenal, pancreas, ovary, testis
Name the major exocrine glands
mammary, liver, bile duct, pancreatic duct
What do endocrine glands secrete? Exocrine glands?
hormones
digestive juices, other products
What are the four types of membranes?
Mucosa, serous, cutaneous and synovial
What are the functions of mucosa?
pathogen trap
gas exchange
nutrient absorption
Mucosa lines a cavity that opens _____________________.
directly to the exterior
Where are mucous membranes found?
nostrils, mouth, lips, eyelids, ears, genital area, anus
What are the function of the epithelial layer of mucosa?
barrier (esp. microbes)
no leaking (tight junctions)
mucous (goblet cells)
digestion (enzymes)
What is the purpose of areolar connective tissue (lamina propria) in a mucous membrane?
supports and binds epithelium, protection, vascular source
Serosa lines a cavity _________________________.
that does not open to the exterior
Name organs protected by serosa
lungs, heart, stomach, intestines
What does a serous membrane consist of?
areolar connective tissue
mesothelium
what does mesothelium secrete?
serous fluid
What are the layers of a serous membrane?
parietal - lines cavity
visceral - lines organ
Which membrane type lacks an epithelial layer?
synovial
What does a synovial membrane consist of?
synoviocytes, which secrete some of the components of synovial fluid
Superficial skin is called?
Deeper skin is called?
epidermis
dermis
What type of membrane is skin?
cutaneous