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121 Cards in this Set

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Normally, what is the reason for seeing folds such as tissues on the body?
To increase SA, which increases cell volume, which means more functions it can do
Cytology:
study of cells
Histology:
study of tissues
Pico/Femto
Pico: 10^12, Femto:10^-15
Gross anatomy:
study of structures visible to unaided eye
Surface anatomy:
refers to general form, morphology and superficial anatomical markings
Regional anatomy:
considers all structures in specific areas of the body, whether superficial or deep
developmental anatomy:
structures that change over time
Embryology:
Study of the first two months of development
comparative anatomy:
considers all different types of animals
clinical anatomy:
focuses on pathological changes during illness
systematic anatomy:
study of one organ system at a time
surgical anatomy:
studies anatomical landmarks for surgical procedures
radiogragph anatomy:
involves study of anatomical structures as they are visualized by x-rays, ultrasound, etc.
Major classes of compounds that make up body
67%water, 20% proteins, 10% lipids, 3% nucleic acids
4 elements that make up 99% of the body
H, O, C, and N
Levels of organization
Cells: smallest living units
Tissues: many cells surrounding material
Organs: combination of tissues
Organ systems: organs combine gto form these
Brief definiation of respiration
is absorption, transport, and use of oxygen by cells
Lymphoid system:
defense against infection and disease
respiratory system:
delivery of air to sites where gas exchange can occur between the air and circulating blood
Urinary system:
elimination of excess water, salts, waste products, and control pH
Reproductive system:
production of sex cells and hormones
Integumentary system:
protection from environmental hazards, temperature control
Skeletel system:
support, protection of soft tissues, mineral storage, blood formation
muscular system:
locomotion, support, heal, production
nervous system:
directing immediate response to stimuli, usually bo coordinating the activites of other organ systems
endocrine system:
directing long-term schanges in activites of other organ systems
cardiovascular system:
internal transport of cells and dissolved material, including nutrients, wastes, and gases
Supine
Prone
Medial
Supine: face up
Prone: face down
Medial: closest towards middle of chest
Umbilical region:
center of stomach
Above belly button:
epigastric region
Below umbilical:
hypogastric region
Looking with the human, right of epigastric:
Right hypochondriac region
Looking with the human, left of epigastric
Left of epigastric region
Looking with the human, right of umbilical:
right lumbar region
Looking with the human, left of the umilical
left lumbar region
Looking with the human, right of hypogastric region
right inguinal region
Looking with the human, left of hypogastric region
Left inguinal region
Anterior:
Posterior:
Inferior:
Superior:
Anterior: towards front
Posterior: towards back
Inferior: bottom
Superior: top
Cranial:
Caudal:
Cranial: toward head
Caudal: toward back(tail)
Proximal:
Distal:
Proximal: moving closer
Distal: moving away
Medial:
Lateral:
Medial: moving toward midline
Lateral: moving away from midline
Saggital plane:
Coronal plane:
Transverse plane:
Saggital: cut down the middle from head in 2 equal parts.
Coronal: exact opposite of saggital, no equal halves, perpendicular to saggital
Transverse: cut them right in half at the waste
Four major functions of cell membrane
physical isolation, regulation of exhange with environment, sensitivity, and structural support
Define equilibrium
When all acting influences or forces are in balance
Define homeostasis
Maintenance of a relatively constant internal environment, such as a thermostat
How is body temperature regulated by homeostasis if body temp rises
Body temp-->body temp rises-->nervous system signals dermal vessels to dilate and sweat glands to secrete-->body heat is lost to its surroundings-->body temp drops toward normal
How is body temperature regulated by homeostasis if body temp lowers
Body temp drops-->nervous system signals dermal blood vessels to constrict and sweat glands to remain inactive-->if body temp continues to drop, then nervous system signals muscles to contract involuntarily-->either body heat is conserved OR muscle activity generates body heat--> body temp rises to nromal
What diffuses and does not diffuse through plasmalemma
Large molecules(lipids) cannot cross plasmalemma unless they are transported by a carrier mechanism. Small water-soluble molecules and ions diffuse thru plasmalemma channels
Define osmosis:
diffusion of water across a selectively permeable membrane
If you have 1% on left, 10% on right, where will water move
Water will move from 1% to 10% to dilute the 10% for equal amounts of salt concentration
Isotonic:
Hypotonic:
Hypertoinc:
Isotonic: equal in concentration
Hypotonic: lower concentration(distilled water)
Hypertonic: higher in concentration(sea water)
If you put a red blood cell in left container with distilled water, what happens to the cell
The cell(0.85%) is going to get bigger until the concentration inside the cell is equal to outside of the cell or it might burst
If you put a red blood cell in sea water what happens?
Cell shrinks
Facilitated diffusion:
cant pass thru phospholipid bilayer, so they need something to facilitate them through
Active transport:
Going from high to low concentration(against conc gradient). Requires ATP and uses enzymes and carrier proteins. (Na,Ca,Mg,K)
Active transport can bring in large amounts of water with ?
Pinocytosis
Exchange pump:
Ion pump that moves two ions simultaneously in opposite directions
phagocytosis: active transport
Phagocytosis makes a phogocytic pocket called psuedopodium that grab bacterium that fuse together to make a phagosome. Phagosome fuses with a lysosome that degrade the cell membrane of the bacterium which then goes to a secondary lysosome and exits with exocytosis
Co-transport:
Symport: S1 and S2 go in
Antiport: S1 and S2 go out
Uniport: just S1 in
Proton pump: bring H's in
Ion pumps in general
Use active transport, more negative inside and more positive outside. Uses ATP which pumps 2K+ in, and 3Na+ out
Atoms
Elements that compose the body. H60%, O26%, C10% all others are less than 1% such as Na, K, Ca, Cl, Mg, P, I, S, Fe
Atoms: Macromolecules
Are many molecules linked together also called polymers
Macromolecules: organic molecules
Must have C, H (proteins, fats, carbs)
Macromolecules: inorganic
Lack C or H and include CO2, O2, H2O and ions
Proteins:
17% of body and are composed of many amino acids linked together (Amino, Hydrogen, Carboxyl, and R group)
Structure of proteins
Primary: sequence of amion acids
Second: a helix, B pleated sheets
Tertiary: buncha spirals
Quaterny: fibrous proteins(collagen) and globular proteins(hemoglobin)
Two important factors of enzymatic reactions
Temperature: increase temp=increase rate. They also alter shape of active site
pH: 1/log[H+], if your H+ conc is 10, pH is 0.5. If it was 100, you're pH would be 1. Blood pH=7.4
Lipids
Make up 15% of body weight and made up of C, H's and some O
Saturated:
Monosaturated:
Polyunsaturated:
Saturated: no dbl C-C bonds
Monosaturated: 1 dbl C-C bond
Polyunsaturated: 2 or more dbl C-C bonds
Triglycerides:
Is the majority of the lipids and is generally called a fat(3 fatty acid chains hooked to glycerol)
Triglycerides: phospholipids
heads are made up of choline, phosphate hooked to glyercol backbone with 2 fatty acid chains
Triglycerides: steroids
cholesterol, estradiol, cortisol, progesterone, and testosterone
Carbohydrates:
source of energy and is 1% of body weight (CHO)
Glycogen:
glucose put together which forms glycogen which is the storage form of glucose
Difference between respiration in the lungs and cellular respiration
Cellular respiration is creating energy(production of ATP) while using oxygen in the mitochondria of the cell. In the lungs it's the exchange of oxygen for CO2
Oxygen and CO2 with regards to capillary beds
More Oxygen in capillary bed than out. Less CO2 in capillary than out
what are the folds of the mitochondria called
Cristae, which form the mitochondrial matrix
What are cytochromes
Enzymes for e- transport
Glycolysis:
Anaerobic, occurs in cytoplasm. Start with glucose(6C), and in the process of cellular respiration you break bonds which release energy that can be harnessed to form new bonds. 40% of bond breaking can be used to form H-Pbonds(ADP-->ATP). 60% is given off as heat. Two glucose bonds are broken. From 1 glucose you end up with 2 pyruvate molecules which have 3 carbons.
Cofactors of glycolysis
FAD+, NAD+
What do you get out of glycolysis?
2ATP, 2NADH2
Transition reaction
Aerobic. Goes into mitochondria and gets converted into 2-acetyl-CoA then goes thru the krebs
What do you get out of the transition step
2NADH2 and CO2
Krebs cycle:
Start out with acetyl-CoA which goes thru krebs.
What do u get out of Krebs cycle
2ATP, 6NADH2, 2FADH2, 4CO2
What produces the CO2's in the krebs cycle
In the transition state, a carbon gets pulled off and in krebs cycle, which produces the CO2's
Electron transport chain
Aerobic. H's are given up from NAD+/FAD+ and they bond to O2 to make H2O
End products of cellular respiratoin
H2O, CO2
Products of cellular respiration are
CO2, H2O, ATP, NAD+&FAD+, and heat
What do epithelial cells provide for us
Cover exposed surfaces of tissues. Line internal passageways and chambers. Product glandular secretions. Are a sheet of cells that provide physical protection, control permeability, provide sensation, and produce secretions
What ARE epithelial cells
Microvilli, sterocelila, cilitated epithelium which maintain the integrity of the epithelium by intercellular connections, attachment to basal lamina(lamina lucida/lamina densa) and epithelial maintenace and renewal is self-perpetuated
Classification of epithelia
Simple: epithelium only has one layer of cells
stratified: epitheium has several layers of cells
Squamous: epithelia is a thinf lat cell
Cuboid: epithelia height equal to their width
Transitional: epithelial changes over time
Columnar: epithelia height is only 3-4 times their width
Superficial fascia:
Hypodermis. between skins and underlying organs. Areolar tissue and adipose tissue.
Deep fascia
Forms strong, fibrous internal framework. Dense connective tissue. Bound to capsules, tendons, ligaments
Subserous fascia
Between serous membranes and deep fascia, areolar tissue
Membranous organelles
Mitochondria, nucleous, ER, golgi, lysosomes, peroxisomes
Nonmenbranous organelles
Cytoskeleton, microvili, centrioles, cilia, flagella, ribosomes
What is plasmalemma made out of?
Lipid bilayer containing phospholipids, steroids, proteins, and carbs.
Function of ribosome
protein synthesis
Function of cilia
Movement during cell division, organization of microtubules
Function of centrosome
strength and support, movement of cellular structures and materials
Function of microvilli
Movement of materials over cell surface
function of cytoskeleton
Increase SA to facilitate absorption of extracellular materials
Function of cytosol
Distributes materials by diffusion, stores glycogen, and pigments
Function of peroxisome:
catabolism of fats
Function of lysoome:
intracellular removal of damaged organelles
Function of golgi:
Storage, alteration, and packing of secretory products
Function of ER:
Synthesis of secretory products, intracellular storage and transport. Lipid, steroid, carb synthesis, Ca ion storage
Function of nucleus
rRNA synthesis, control metabolism
What are ribosomes made out of
60% RNA, 40% protein
What does connective tissue do
Fill internal spaces, provide structural support and store energy
What do muscle tissue and neural tissue do
Muscle contracts to produce active movement. Neural tissue conducts electrical impulses and carries info
Element that is most abundant inside cell
K+
Outside: Na, Ca, Mg, Cl
--More negative charge inside cell
Explain receptor-mediated endocytosis
Ligands bind to receptors. An opening occurs with ligands bound to receptors in the outside of the hole. A coated vesicle forms. Primary lysosome fuses and creates secondary lysosome. THen the ligands are removed and then goes back out as a vesicle with no ligands
Our only responsibility as a dissector
preservation of body to prevent it from becoming to dry
Method of dissecting the body
regional one
Abduction:
Adduction:
Ab: Away from midline
Add: toward midline
Supination(lateral rotation)
Pronation(medial rotation)
Supination: thumb away from body(anatomical position)
Pronation: thumb is moved towards leg
Receptor-mediated endocytosis(better explanation)
Process by which cells internalize molecules by the inward budding of the plasma membrane vesicles containing p roteins with receptor sites specific to the molecules being internalized
How receptor-mediated endocytosis happens
After binding gof ligand to plasma membrane spanning receptors, signals is sent thru membbrane leading to membrane coating and formation of membrane invagination. Receptor and its ligand are opsonized in clathrin-coated vesicles. They then uncoat and individual vesicles fuse to form an early endosome. The system is saturable and uptake will decline until receptors are recycled to the surface