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121 Cards in this Set
- Front
- Back
Normally, what is the reason for seeing folds such as tissues on the body?
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To increase SA, which increases cell volume, which means more functions it can do
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Cytology:
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study of cells
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Histology:
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study of tissues
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Pico/Femto
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Pico: 10^12, Femto:10^-15
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Gross anatomy:
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study of structures visible to unaided eye
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Surface anatomy:
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refers to general form, morphology and superficial anatomical markings
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Regional anatomy:
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considers all structures in specific areas of the body, whether superficial or deep
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developmental anatomy:
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structures that change over time
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Embryology:
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Study of the first two months of development
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comparative anatomy:
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considers all different types of animals
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clinical anatomy:
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focuses on pathological changes during illness
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systematic anatomy:
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study of one organ system at a time
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surgical anatomy:
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studies anatomical landmarks for surgical procedures
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radiogragph anatomy:
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involves study of anatomical structures as they are visualized by x-rays, ultrasound, etc.
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Major classes of compounds that make up body
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67%water, 20% proteins, 10% lipids, 3% nucleic acids
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4 elements that make up 99% of the body
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H, O, C, and N
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Levels of organization
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Cells: smallest living units
Tissues: many cells surrounding material Organs: combination of tissues Organ systems: organs combine gto form these |
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Brief definiation of respiration
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is absorption, transport, and use of oxygen by cells
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Lymphoid system:
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defense against infection and disease
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respiratory system:
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delivery of air to sites where gas exchange can occur between the air and circulating blood
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Urinary system:
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elimination of excess water, salts, waste products, and control pH
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Reproductive system:
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production of sex cells and hormones
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Integumentary system:
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protection from environmental hazards, temperature control
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Skeletel system:
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support, protection of soft tissues, mineral storage, blood formation
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muscular system:
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locomotion, support, heal, production
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nervous system:
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directing immediate response to stimuli, usually bo coordinating the activites of other organ systems
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endocrine system:
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directing long-term schanges in activites of other organ systems
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cardiovascular system:
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internal transport of cells and dissolved material, including nutrients, wastes, and gases
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Supine
Prone Medial |
Supine: face up
Prone: face down Medial: closest towards middle of chest |
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Umbilical region:
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center of stomach
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Above belly button:
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epigastric region
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Below umbilical:
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hypogastric region
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Looking with the human, right of epigastric:
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Right hypochondriac region
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Looking with the human, left of epigastric
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Left of epigastric region
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Looking with the human, right of umbilical:
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right lumbar region
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Looking with the human, left of the umilical
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left lumbar region
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Looking with the human, right of hypogastric region
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right inguinal region
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Looking with the human, left of hypogastric region
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Left inguinal region
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Anterior:
Posterior: Inferior: Superior: |
Anterior: towards front
Posterior: towards back Inferior: bottom Superior: top |
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Cranial:
Caudal: |
Cranial: toward head
Caudal: toward back(tail) |
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Proximal:
Distal: |
Proximal: moving closer
Distal: moving away |
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Medial:
Lateral: |
Medial: moving toward midline
Lateral: moving away from midline |
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Saggital plane:
Coronal plane: Transverse plane: |
Saggital: cut down the middle from head in 2 equal parts.
Coronal: exact opposite of saggital, no equal halves, perpendicular to saggital Transverse: cut them right in half at the waste |
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Four major functions of cell membrane
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physical isolation, regulation of exhange with environment, sensitivity, and structural support
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Define equilibrium
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When all acting influences or forces are in balance
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Define homeostasis
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Maintenance of a relatively constant internal environment, such as a thermostat
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How is body temperature regulated by homeostasis if body temp rises
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Body temp-->body temp rises-->nervous system signals dermal vessels to dilate and sweat glands to secrete-->body heat is lost to its surroundings-->body temp drops toward normal
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How is body temperature regulated by homeostasis if body temp lowers
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Body temp drops-->nervous system signals dermal blood vessels to constrict and sweat glands to remain inactive-->if body temp continues to drop, then nervous system signals muscles to contract involuntarily-->either body heat is conserved OR muscle activity generates body heat--> body temp rises to nromal
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What diffuses and does not diffuse through plasmalemma
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Large molecules(lipids) cannot cross plasmalemma unless they are transported by a carrier mechanism. Small water-soluble molecules and ions diffuse thru plasmalemma channels
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Define osmosis:
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diffusion of water across a selectively permeable membrane
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If you have 1% on left, 10% on right, where will water move
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Water will move from 1% to 10% to dilute the 10% for equal amounts of salt concentration
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Isotonic:
Hypotonic: Hypertoinc: |
Isotonic: equal in concentration
Hypotonic: lower concentration(distilled water) Hypertonic: higher in concentration(sea water) |
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If you put a red blood cell in left container with distilled water, what happens to the cell
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The cell(0.85%) is going to get bigger until the concentration inside the cell is equal to outside of the cell or it might burst
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If you put a red blood cell in sea water what happens?
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Cell shrinks
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Facilitated diffusion:
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cant pass thru phospholipid bilayer, so they need something to facilitate them through
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Active transport:
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Going from high to low concentration(against conc gradient). Requires ATP and uses enzymes and carrier proteins. (Na,Ca,Mg,K)
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Active transport can bring in large amounts of water with ?
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Pinocytosis
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Exchange pump:
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Ion pump that moves two ions simultaneously in opposite directions
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phagocytosis: active transport
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Phagocytosis makes a phogocytic pocket called psuedopodium that grab bacterium that fuse together to make a phagosome. Phagosome fuses with a lysosome that degrade the cell membrane of the bacterium which then goes to a secondary lysosome and exits with exocytosis
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Co-transport:
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Symport: S1 and S2 go in
Antiport: S1 and S2 go out Uniport: just S1 in Proton pump: bring H's in |
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Ion pumps in general
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Use active transport, more negative inside and more positive outside. Uses ATP which pumps 2K+ in, and 3Na+ out
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Atoms
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Elements that compose the body. H60%, O26%, C10% all others are less than 1% such as Na, K, Ca, Cl, Mg, P, I, S, Fe
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Atoms: Macromolecules
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Are many molecules linked together also called polymers
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Macromolecules: organic molecules
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Must have C, H (proteins, fats, carbs)
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Macromolecules: inorganic
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Lack C or H and include CO2, O2, H2O and ions
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Proteins:
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17% of body and are composed of many amino acids linked together (Amino, Hydrogen, Carboxyl, and R group)
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Structure of proteins
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Primary: sequence of amion acids
Second: a helix, B pleated sheets Tertiary: buncha spirals Quaterny: fibrous proteins(collagen) and globular proteins(hemoglobin) |
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Two important factors of enzymatic reactions
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Temperature: increase temp=increase rate. They also alter shape of active site
pH: 1/log[H+], if your H+ conc is 10, pH is 0.5. If it was 100, you're pH would be 1. Blood pH=7.4 |
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Lipids
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Make up 15% of body weight and made up of C, H's and some O
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Saturated:
Monosaturated: Polyunsaturated: |
Saturated: no dbl C-C bonds
Monosaturated: 1 dbl C-C bond Polyunsaturated: 2 or more dbl C-C bonds |
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Triglycerides:
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Is the majority of the lipids and is generally called a fat(3 fatty acid chains hooked to glycerol)
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Triglycerides: phospholipids
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heads are made up of choline, phosphate hooked to glyercol backbone with 2 fatty acid chains
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Triglycerides: steroids
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cholesterol, estradiol, cortisol, progesterone, and testosterone
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Carbohydrates:
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source of energy and is 1% of body weight (CHO)
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Glycogen:
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glucose put together which forms glycogen which is the storage form of glucose
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Difference between respiration in the lungs and cellular respiration
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Cellular respiration is creating energy(production of ATP) while using oxygen in the mitochondria of the cell. In the lungs it's the exchange of oxygen for CO2
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Oxygen and CO2 with regards to capillary beds
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More Oxygen in capillary bed than out. Less CO2 in capillary than out
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what are the folds of the mitochondria called
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Cristae, which form the mitochondrial matrix
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What are cytochromes
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Enzymes for e- transport
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Glycolysis:
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Anaerobic, occurs in cytoplasm. Start with glucose(6C), and in the process of cellular respiration you break bonds which release energy that can be harnessed to form new bonds. 40% of bond breaking can be used to form H-Pbonds(ADP-->ATP). 60% is given off as heat. Two glucose bonds are broken. From 1 glucose you end up with 2 pyruvate molecules which have 3 carbons.
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Cofactors of glycolysis
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FAD+, NAD+
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What do you get out of glycolysis?
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2ATP, 2NADH2
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Transition reaction
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Aerobic. Goes into mitochondria and gets converted into 2-acetyl-CoA then goes thru the krebs
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What do you get out of the transition step
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2NADH2 and CO2
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Krebs cycle:
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Start out with acetyl-CoA which goes thru krebs.
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What do u get out of Krebs cycle
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2ATP, 6NADH2, 2FADH2, 4CO2
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What produces the CO2's in the krebs cycle
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In the transition state, a carbon gets pulled off and in krebs cycle, which produces the CO2's
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Electron transport chain
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Aerobic. H's are given up from NAD+/FAD+ and they bond to O2 to make H2O
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End products of cellular respiratoin
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H2O, CO2
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Products of cellular respiration are
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CO2, H2O, ATP, NAD+&FAD+, and heat
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What do epithelial cells provide for us
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Cover exposed surfaces of tissues. Line internal passageways and chambers. Product glandular secretions. Are a sheet of cells that provide physical protection, control permeability, provide sensation, and produce secretions
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What ARE epithelial cells
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Microvilli, sterocelila, cilitated epithelium which maintain the integrity of the epithelium by intercellular connections, attachment to basal lamina(lamina lucida/lamina densa) and epithelial maintenace and renewal is self-perpetuated
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Classification of epithelia
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Simple: epithelium only has one layer of cells
stratified: epitheium has several layers of cells Squamous: epithelia is a thinf lat cell Cuboid: epithelia height equal to their width Transitional: epithelial changes over time Columnar: epithelia height is only 3-4 times their width |
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Superficial fascia:
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Hypodermis. between skins and underlying organs. Areolar tissue and adipose tissue.
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Deep fascia
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Forms strong, fibrous internal framework. Dense connective tissue. Bound to capsules, tendons, ligaments
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Subserous fascia
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Between serous membranes and deep fascia, areolar tissue
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Membranous organelles
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Mitochondria, nucleous, ER, golgi, lysosomes, peroxisomes
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Nonmenbranous organelles
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Cytoskeleton, microvili, centrioles, cilia, flagella, ribosomes
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What is plasmalemma made out of?
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Lipid bilayer containing phospholipids, steroids, proteins, and carbs.
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Function of ribosome
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protein synthesis
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Function of cilia
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Movement during cell division, organization of microtubules
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Function of centrosome
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strength and support, movement of cellular structures and materials
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Function of microvilli
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Movement of materials over cell surface
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function of cytoskeleton
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Increase SA to facilitate absorption of extracellular materials
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Function of cytosol
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Distributes materials by diffusion, stores glycogen, and pigments
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Function of peroxisome:
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catabolism of fats
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Function of lysoome:
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intracellular removal of damaged organelles
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Function of golgi:
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Storage, alteration, and packing of secretory products
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Function of ER:
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Synthesis of secretory products, intracellular storage and transport. Lipid, steroid, carb synthesis, Ca ion storage
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Function of nucleus
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rRNA synthesis, control metabolism
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What are ribosomes made out of
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60% RNA, 40% protein
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What does connective tissue do
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Fill internal spaces, provide structural support and store energy
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What do muscle tissue and neural tissue do
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Muscle contracts to produce active movement. Neural tissue conducts electrical impulses and carries info
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Element that is most abundant inside cell
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K+
Outside: Na, Ca, Mg, Cl --More negative charge inside cell |
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Explain receptor-mediated endocytosis
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Ligands bind to receptors. An opening occurs with ligands bound to receptors in the outside of the hole. A coated vesicle forms. Primary lysosome fuses and creates secondary lysosome. THen the ligands are removed and then goes back out as a vesicle with no ligands
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Our only responsibility as a dissector
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preservation of body to prevent it from becoming to dry
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Method of dissecting the body
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regional one
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Abduction:
Adduction: |
Ab: Away from midline
Add: toward midline |
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Supination(lateral rotation)
Pronation(medial rotation) |
Supination: thumb away from body(anatomical position)
Pronation: thumb is moved towards leg |
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Receptor-mediated endocytosis(better explanation)
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Process by which cells internalize molecules by the inward budding of the plasma membrane vesicles containing p roteins with receptor sites specific to the molecules being internalized
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How receptor-mediated endocytosis happens
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After binding gof ligand to plasma membrane spanning receptors, signals is sent thru membbrane leading to membrane coating and formation of membrane invagination. Receptor and its ligand are opsonized in clathrin-coated vesicles. They then uncoat and individual vesicles fuse to form an early endosome. The system is saturable and uptake will decline until receptors are recycled to the surface
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