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34 Cards in this Set
- Front
- Back
Water Soluble Hormones
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adrenaline, noradrenaline, epinephrine, norepinephrine, melatonin, tsh, hgh
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lipid soluble hormones
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testosterone, progesterone, oestrogen, cortisone, alderosterone
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how are water soluble hormones transported
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free floating in plasma
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how are lipid soluble hormones transported
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bind to transport proteins
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how do water soluble hormones act on cells
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act on plasma membrane receptors act via g protein messengers cannot enter cell |
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how do lipid soluble hormones act on cells
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act on intracellular receptors that directly activate genes, can enter cell
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what three factors determine the sensitivity of a cell to a particular hormone |
blood levels of hormone # of target cell receptors affinity of receptor for hormone |
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Three Types of Stimuli a gland may respond to
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humoral hormonal neural |
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Humoral Stimuli
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changing blood levels of ions and nutrients directly stimulate secretion of hormones
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Hormonal Stimuli
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hormones stimulate other endocrine organs to release their hormones
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Neural Stimuli
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nerve fibers stimulate hormone release
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Negative Feedback Loop for Thyroid (thyroxine)
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rising TH levels provide negative feedback inhibition on release of TSH
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NFL of Gonads
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GnRH production
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NFL of Pancreas
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rise in blood glucose stimulates release of insulin
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NFL of Thyroid/Parathyroid
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Rising Ca in blood inhibits PTH release
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Physiologic Purpose of Lymphatic System
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to return proteins and fluids to blood immune response to bacteria |
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Macrophages
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phagocytize foreign substances, help activate T cells
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Dendritic Cells
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capture antigens and deliver them to lymph nodes
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T cells
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manage immune response, detect and destroy infected cells
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B cells
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produce plasma cells which secrete antibodies
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lymph
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contains nutrients, oxygen, hormones, and fatty acids as well as toxins and cellular waste products that are transported to and from cellular tissues
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lymphatic vessels
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transport lymph from peripheral tissues to the veins of the cardiovascular system
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lymph nodes
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monitor composition of lymph, and immunologic response
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spleen
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monitors blood composition, immunologic response
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thymus
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serves as the site of T-lymphocyte maturation, development, and control
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Spleen differs from other lymphoid organs
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largest blood filter |
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thymus differs from other lymphoid organs
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most active during childhood increases in size then decreases in size from adolescence through old age |
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role and function of MALT
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regulates mucosal immunity protects from pathogens trying to enter body |
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parathyroid gland
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releases PTH, which raises blood Ca levels and is activated humorally by low Ca levels
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Thyroid gland
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T3 and T4, which control metabolism and is activated hormonally by TSH
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Adrenal Cortex
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releases cortisol and aldosterone, cortisol helps regulate metabolism and helps body respond to stress. Aldosterone controls BP. both activated hormonally by ACTH
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adrenal medulla
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catecholamines
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pituitary
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FSH - spermatogenesis Prolactin - stimulates growth of mammary glands and lactation Leutinizing Hormone - stimulates ovulation |
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Gonads
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Inhibin - inhibits secretion of follicle stimulating hormone
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