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34 Cards in this Set

  • Front
  • Back
Water Soluble Hormones
adrenaline, noradrenaline, epinephrine, norepinephrine, melatonin, tsh, hgh
lipid soluble hormones
testosterone, progesterone, oestrogen, cortisone, alderosterone
how are water soluble hormones transported
free floating in plasma

how are lipid soluble hormones transported
bind to transport proteins
how do water soluble hormones act on cells

act on plasma membrane receptors


act via g protein messengers


cannot enter cell

how do lipid soluble hormones act on cells
act on intracellular receptors that directly activate genes, can enter cell

what three factors determine the sensitivity of a cell to a particular hormone


blood levels of hormone


# of target cell receptors


affinity of receptor for hormone

Three Types of Stimuli a gland may respond to

humoral


hormonal

neural


Humoral Stimuli
changing blood levels of ions and nutrients directly stimulate secretion of hormones
Hormonal Stimuli
hormones stimulate other endocrine organs to release their hormones
Neural Stimuli
nerve fibers stimulate hormone release
Negative Feedback Loop for Thyroid (thyroxine)
rising TH levels provide negative feedback inhibition on release of TSH
NFL of Gonads
GnRH production
NFL of Pancreas
rise in blood glucose stimulates release of insulin
NFL of Thyroid/Parathyroid
Rising Ca in blood inhibits PTH release
Physiologic Purpose of Lymphatic System

to return proteins and fluids to blood

immune response to bacteria


Macrophages
phagocytize foreign substances, help activate T cells
Dendritic Cells
capture antigens and deliver them to lymph nodes
T cells
manage immune response, detect and destroy infected cells

B cells
produce plasma cells which secrete antibodies
lymph
contains nutrients, oxygen, hormones, and fatty acids as well as toxins and cellular waste products that are transported to and from cellular tissues
lymphatic vessels
transport lymph from peripheral tissues to the veins of the cardiovascular system
lymph nodes
monitor composition of lymph, and immunologic response
spleen
monitors blood composition, immunologic response
thymus
serves as the site of T-lymphocyte maturation, development, and control
Spleen differs from other lymphoid organs

largest


blood filter

thymus differs from other lymphoid organs

most active during childhood


increases in size then decreases in size from adolescence through old age

role and function of MALT

regulates mucosal immunity

protects from pathogens trying to enter body


parathyroid gland
releases PTH, which raises blood Ca levels and is activated humorally by low Ca levels
Thyroid gland
T3 and T4, which control metabolism and is activated hormonally by TSH
Adrenal Cortex
releases cortisol and aldosterone, cortisol helps regulate metabolism and helps body respond to stress. Aldosterone controls BP. both activated hormonally by ACTH
adrenal medulla
catecholamines
pituitary

FSH - spermatogenesis


Prolactin - stimulates growth of mammary glands and lactation


Leutinizing Hormone - stimulates ovulation

Gonads
Inhibin - inhibits secretion of follicle stimulating hormone