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43 Cards in this Set

  • Front
  • Back

Microanatomy of the testes

Seminiferous tubules = Produce sperm



Sertoli/Nurse cells = Secretes testicular fluid



Interstitial cells = secrete testosterone

Sertoli or Nurse cells location and function

Location = Seminiferous tubule



Functions:


-deliever nutrients to dividing cells


-Secrete testicular fluid


-secret inhibin (regulates spermatogenesis by inhibiting FSH and LH)


-Forms blood/testes barrier to protect sperm from immune system

Duct system anatomy

Epididymis = maturation and storage for sperm



Ductus (Vas) deferens = transport sperm



Ejaculatory duct = mixes secretions to create sperm



Urethra = carries both urine and semen

Accessory glands

Seminal vesicles = contains fructose to nourish sperm



Prostate gland = secretes acidic fluid which activates sperm



Bulbourethral (Cowper's) gland = secretions contains mucus for lubrication

2 major tissues of the penis

1. Corpus spongiosum = mass of spongy tissue surrounding the urethra; maintains a patent urethra



2. Corpora Cavernosa = A pair of sponge-like regions of erectile tissue which contain most of the blood in the penis during erection

Male reproductive physiology cycles

Spermatogenesis - process produces 4 haploid sperm from 1 diploid stem cell



3 processes occur:


-Mitosis


-Meiosis I and II


-Spermiogenesis

Spermatogenesis - prenatal to puberty

Mitosis occurs = cell division producing clones


•Spermatogonia = Diploid cells (46 chromosomes)


•Location = epithelial lining of seminiferous tubules


•Function = Divide mitotically until puberty



● Spermatogonia differentiate to become a primary spermatocyte

Spermatogenesis: puberty - death

Meiosis occurs = requiring 2 divisions to reduce chromosome number in half



Meiosis I = Start with primary spermatocyte (2n) divides end with 2 secondary spermatocytes (N)



Meiosis II = Start 2 secondary spermatocyte (N) divide and end with 4 spermatids (N)

GNRH (hormone)

Stimulates the release of FSH and LH from Ant Pit

FSH (hormone)

Released from ant pit



Function = stimulates maturation of sex cells

LH (hormone)

Released from ant pit



Function = stimulates interstitial cells to produce testosterone

Testosterone function

Function = develops secondary sexual characteristics; muscle and bone growth

Inhibin (hormone)

Function = inhibits FSH

Structure of sperm cell

1. Head


a. Nucleus


b. Acrosome


2. Midpiece


- lots of mitochondria


3. Tail

The hypothalamus releases...

GnRH to ant pit

Anterior pituitary secretes:

•Follicle stimulating hormone (FSH) = Stimulates spermatogenesis



• Luteinizing hormone (LH) = Stimulates testosterone release

Ovaries: structure & function

Structure - outer connective tissue layer for support



Function


•Produce female gamete


•hormones = estrogen and progesterone

Duct system (Female)

Uterine/fallopian tubes = recieve ovulated oocyte by fimbrae sweeping it into tube


•site of fertilization and tubal ligation



Uterus = site of implantation/fetal growth



Vagina = passageway for fetus/menstrual flow


•pH acidic = inhibits microbial growth, keeps vagina healthy

Uterus - 3 layers

1. Perimetrium = outermost layer


2. Myomentrium = smooth muscle layer that contracts during childbirth (Oxytocin induced)


3. Endometrium = Mucosa layer where fertilized egg implants



4. Cervix = outlet to vagina

External Genitalia (Vulva) structure

Mons pubis = fatty rounded area covered w/ pubic hair overlying pubic symphysis



Labia majora = hair covered fatty skin folds homologous to scrotum



Labia minora = encloses urethra opening and vagina



Clitoris = contains erectile tissue homologous to penis

Oogenesis

•process which produces 1 viable oocyte (haploid) and 3 polar bodies



•occurs in ovary



• 3 processes involved


1. Mitosis = prenatally


2. Meiosis I =Begins prenatally, then monthly


3. Meiosis II = Completed only if fertilization occurs

Oogonia multiply by....

Mitosis

All oogonua become __ oocytes surrounded by 1 layer of cells called ___

Primary


Primordial follicle

A "follicle" =

An oocyte and the granulosa/follicular cells surrounding it

Meiosis I ends with...

Secondary oocyte = contains most organelles due to unequal cytokinesis



Polar Body = Small cell containing nucleus

Meiosis II starts with...

Secondary oocyte


One polar body

Upon fertilization you end meiosis II with...

One secondary oocyte


3 polar bodies

Ovulation occurs around day....

14 of cycle

Describe ovulation

Follicle at most mature stage ejects the secondary oocyte and polar body together

Corona radiata

Layer of cells surrounding the oocyte to protect and nourish

Zona pellucida

Membrane with receptors to bind with sperm

Loss of estrogen causes...

Breakdown of bones



Cardiovascular problems



Atrophy of reproductive organs and breasts

3 stages of ovarian cycle...

Follicular phase = day 1 - 12


Ovulation = day 12- 14


Luteal phase = day 15 - 28

3 stages of uterine cycle...

Menstrual Phase = day 1 - 5


Proliferative phase = day 6 - 12


Secretory phase = day 15 - 28

In ovulation LH surges which causes...

Ovary wall to rupture releasing secondary oocyte

During the luteal phase, LH stimulates...

Granulosa cells of corpus luteum to secrete progesterone and estrogen

Progesterone and estrogen functions

Maintains endometrium in uterus

Low progesterone levels cause...

Endometrial lining to shed = menses

Estrogen stimulates...

Repair of endometrium lining by increasing mitosis

Progesterone stimulates endometrium to...

To prepare for implantation to grow by increasing blood supply and mucus secretions

Progesterone also stimulates formation of cervical plug =

Block sperm entry

When there is no implantation...

Progesterone levels fall due to luteum deterioration



Uterine arteries spasm cutting off blood supply



Endometrial cells die = lost as menses

hCG maintains corpus luteum which continues to...

Produce progesterone to maintain endometrial lining