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195 Cards in this Set
- Front
- Back
How Information is recievied
Analog vs. Digital |
Analog - is how everything comes in from the world around
Digital - how we process the world around us. It is All or None - On or Off (Action Potential) |
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Three overlapping functions of nervous system
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Sensory Input - Gathered information
Integration - Process and interprets sensory input, the decides what should be done with it Motor Output - the actual respones required after integration |
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(3) parts to a typical nerve
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Cell body - inside CNS its a cell body, outside its a ganglion
dendrites - Axons - tracts for information |
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Definition of ganglion
Definition of Nuclei |
ganglion - cell body in CNS
Nuclei - cell body outside CNS |
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Description of a Neuron
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High longevity - lasts a longtime
Amitotic - has no mitosis, so when it is damaged, it wont grow back High metabolism - uses lots of ATP Needs support cells - called neuroglia, w/o it will die |
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Types of Neuroglia (support cells) in CNS
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Astrocyte
microglia ependymal oligodendrocyte |
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Neuroglia - Astrocyte
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-helps transport nutrients in and out of neuron
-absorbs extra neurotransmitters and K+ ions may play a role in nerve transmission |
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Neuroglia - Microglia
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-macrophage like languherhans cell
-acts like immune -cells of immune system are denied access to CNS |
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Neuroglia - Ependymal
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-mostly columnar and ciliated
-circulate spinal fluid -line inner portion of surrounding spinal cord |
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Neuroglia - Oligodendrocyte
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-Same as Schwann cell, but in CNS
-Produces myelin sheath in white matter |
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Support cells in Parasympathetic system
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-Satellite cells
-Schwann cell |
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Neuroglia (PNS)- Satellite Cells
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-wrap around cell body
-help maintain cell body |
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Neuroglia (PNS)- Schwann Cell
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-produce Schwann sheath (myelin sheath)
-produces myelin (membrane) - wraps neuron in myelin for insulation - speeds up process - has outer most layer called neurolemma |
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Characteristics of Myelin
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- myelin is made of fat
- myelin is non polar - myelin is used for insulation - outermost layer called neurolemma |
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Neurolemma
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-outermost layer of myelin (Schwann) sheath
-it is nucleated and cytoplasmic -encloses myelin sheath |
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Structure of Neuron
- Dendrite |
- carry impulse to body
- has branching extensions of membranes containing cytoplasm - same organelles as body - graded potential - lots of Rough Endoplasmic reticulum (nissel bodies) -produces protiens -tansports w/ cytoskeleton - final destination is synaptic end bulbs - usually not mylennated |
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Structure of Neuron
- Body |
- Nucleus
- Mitochondria, Golgi, Lysosomes - Lack centrioles - RER (Nissl bodies) -chromatophilic b/c they stain dark |
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Structure of Neuron
- axon hillock |
- Highly excitable
- AP originates here - transition from Graded Potential to Action Potentional - Neural integrators count excitatory and inhibitory impulses |
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Structure of Neuron
- axon |
- lead away from cell body
- collaterals - telodendria - synaptic knobs - classified via structure or function |
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Stucture of neuron
- axon - collaterals |
- collaterals - side branches
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Structure of Neuron
- Axon - Telodendria |
Axon terminal branches divided into hundrends and thousands
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Stucture of Neuron
- Axon - Synaptic Knobs |
contains neurotransmitters which are protiens and peptides
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Stucture of neuron
- Axon - Classification via structure |
- Multipolar - 3 or more processes (axons/dendrites)
- most common in CNS - Bipolar - 2 processes - dendrites converge into one before getting to axon - found in CNS (Retina) - unipolar - one axon opening to cell body - w/ ganglia in periphreal nervous system - outside CNS |
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Structure of Neuron
- Axon - classification via function |
- sensory - afferent
- all are unipolar - w/ cellbodies outside CNS - motor - efferent (effect) - multipolar - inside CNS - Interneurons - association - lie between sensory and motor neurons - make up 99% of neurons in body - most in CNS - multipolar |
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Transmission
- voltage |
Potential Energy between 2 points that have different charges
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Transmission
- potential |
- Difference between 2 charges at give voltage/electrical voltage difference across membrane
- separated charges of oppostie sign |
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Transmission
- at rest |
- Resting potential = -70 mV
- -70 mV created by Disequilibrium - Disequilibrium is created by Na+ K+ pump |
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Transmission
- channels |
- voltage gated - opens w/ voltage
- only in axons - ligand - opens in response to chemical stimulus - only in dendrites - Mechanical - opens in response to mechanical stimulus - only in dendrites |
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Transmission
- Graded Potental |
- Analog information
- Originates from cell body or dendrites - different names depending on stimulus (EPSP or IPSP or others) - is ligand or mechancial gated - Varies in amplitude depending on strength of stimulus - Localized - short lived, doesn't go far |
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Transmission
- Action Potential |
- Voltage gated
- originates in Axon - it is all or none - On or Off - long lived, can travel long way - |
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Interpretation of Action potential
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* Na+ gates open
- -55 mV threshold is broken - quick depolarization occurs - voltage drops to 0 - at +30 mV - Na+ gates close, K+ gates open - called repolarization - at -74 mV - Hyperpolarization occurs - Na+ K+ pump operates to restore -70 mV resting |
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Interpretation travels in a ...
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Wave!!!
- travels down the axon - known as prpagation - carried via microtubules - only in one direction (towards telodendria) |
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Schwann cells
- other characteristics |
- have no gates
- located at Node of Ranvier - Saltatation - wave skips from node to node - depolarization in this way saves energy |
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Node of Ranvier
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- Patches of exposed neuron
- gaps in the myelin (schwann)sheath - information exchange takes place in these gaps |
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Graded Potential
- further information |
- different names depending on location/orgin
- does not propagate itself - very isolated signal - IPSP - Inhibitory Post Synaptic Potential - hyperpolarized, causes the membrane potential to be more (-) - nerve impulse must go further to break -55 mV threshhold - EPSP - excitatiory post synaptic potential - depoarliezed, causing membrane potential to be less (-) - nerve impulse has less difficulty breaking -55 mV threshold *** view graphs*** |
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Synapapse-Neurotransmitter
- Presynaptic |
- Ca2+ voltage gates open
- breaks actin - Synaptic vesicle drops - releasing neurotransmitter |
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Synapapse-Neurotransmitter
- Post synaptic |
- Differing types of Graded Potential
- temporal summation - spatial summation |
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Synapapse-Neurotransmitter
- Post synaptic - Summation |
- summation means that the greater the EPSP, the more likely the chance of breaking the -55 mV threshold
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Synapapse-Neurotransmitter
- Post synaptic - Temporal Summation |
when summation results from the build up of neurotransmitter released by a sungle bulb 2 or 3 times in rapid succession
bang-bang-bang-bang-bang |
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Synapapse-Neurotransmitter
- Post synaptic - Spatial Summation |
When summation results from the build up of neurotransmitters released simultaneously by several presynaptic end bulbs
BOOM!!!!!! |
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Neurotransmitters
- criteria to be called one... |
- must be stored and released from presynaptic end bubls
- must cause either an EPSP or IPSP - must be naturally removed from synaptic cleft by enzyme/diffusion/uptake (ACh-ase) |
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Neurotransmitters
- (5) groups |
1 - Acetylcholine (ACh)
2 - Amino Acids 3 - Peptides 4 - Novel 5 - Biogenic Amines |
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Neurotransmitters
- Acetylcholine (ACh) |
- Neuromuscular
- can be either EPSP or IPSP depending on receptors - Cardiac IPSP - Skeletal EPSP |
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Neurotransmitters
- Amino Acids |
- Only found in CNS
- (3)specific examples - Glycine - Glutamate - GABA |
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Neurotransmitters
- Amino Acids - Glycine |
- IPSP
- makes up half of the neurotransmitters in the spinal cord (other half is GABA) - Strychnine blocks its receptors |
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Neurotransmitters
- Amino Acids - Glutamate |
- EPSP
- Important for learning and memory - during stroke, excessive release causes neurons to be stimulated to death |
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Neurotransmitters
- Amino Acids - GABA |
- Gamma Amino Btyric Acid
- IPSP - Common in the brain - Valium and alcohol enhance action of GABA |
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Neurotransmitters
- Peptides |
- small chains of 30 to 40 amino acids
- (3) specific examples - Endorphins - Substance P - Somatostatin & Cholecystokinin |
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Neurotransmitters
- Peptides - Endorphins |
- Opiates
- pleasure - natural pain killer |
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Neurotransmitters
- Peptides - Substance P |
- Found where there is pain
- lets body know it is experiencing pain |
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Neurotransmitters
- Peptides - Somatostatin & Cholecystokinin |
- produced by tissues in the GI tract
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Neurotransmitters
- Novel |
(3) specific examples
- ATP - Nitric Oxide - Carbon Monoxide |
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Neurotransmitters
- Novel - ATP |
- Adenosine tri-phosphate
- can be either EPSP or IPSP - can be found in both CNS and PNS - Provokes pain sensation |
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Neurotransmitters
- Novel - Carbon monoxide |
- EPSP
- Causes pain, sensitivity to pain |
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Neurotransmitters
- Novel -Nitic Oxide |
- EPSP
- causes smooth muscle to relax - release increases stroke damage - used to treat male impotence |
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Neurotransmitters
- Biogenic Amines |
- can be EPSP Or IPSP depending on receptors
- Variations on Amino Acids - 3 generators and their neurotransmitters - Tryptophan ...serotonin - Histamine ... histamine - Tyrosine ... dopamine, epinephrine, norepinephrine |
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Neurotransmitters
- Biogenic Amines - Tryptophan |
- found in turkey
- makes serotonin - plays a role in sleep, appetite, migraines, - LSD blocks serotonin receptors - too little serotonin causes depression - prozac affects uptake, leaving serotonin in synapse longer |
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Neurotransmitters
- Biogenic Amines - Histamine |
- Cause inflamation
- helps blood to reach areas that need to heal |
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Neurotransmitters
- Biogenic Amines - Tyrosine |
- depending on enzyme, synthesizes:
- Dopamine - Epinephrine - Norepinephrine |
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Neurotransmitters
- Biogenic Amines - Tyrosine - Dopamine |
- makes you feel good
- Parkinson's disease has TOO LITTLE DOPAMINE - Schizophrenic has TOO MUCH DOPAMINE - Chlorozine and heldal bind dopamine, stopping it from working - Amphetamines increase dopamione release - cocaine blocks dopamine receptors |
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Neurotransmitters
- Biogenic Amines - Tyrosine - Epinephrine and Norepinephrine |
- essentially adrenaline
- made by the adrenal gland - make you feel good - amphetamines increase production - antidepressants and cocaine block removal from synapse |
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Receptors in Autonomic Nervous System
- (3) Types |
- Nicotinic (cholinergic receptor)
- Muscarinic (cholinergic receptor) - Adrenergic (sensative to NE and epinephrine) |
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Receptors in Autonomic Nervous System
- Nicotinic |
- ACh receptor
- stimulate EPSP - located in plasma membrane of dendrites and cell bodies of both Sympathetic and Parasympathetic postganglion neurons - also found in neuromuscular junction |
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Receptors in Autonomic Nervous System
- Muscarinic |
- ACh receptor
- IPSP for Cardiac - EPSP for GI tract(intestines) - receptors located in plasma membrane of effectors of Parasympathetic postganglions - used in cardiac, smooth, and glands |
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Receptors in Autonomic Nervous System
- Adrenergic - with (2) types |
- receptor for Norepinephrine and epinephrine
- located at most sympathetic postganglion neuorns - alpha usually stimulates - beta usually inhibits - for cardiac it is an IPSP - beta blockers block receptors for beta |
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Embryonic Development
- 1st system to develop... |
Nervous System
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Neural Plate
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- Embryonic origin of all neural tissue
- site where ectoderm thickens |
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Neural groove
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Neural plate folds inward to form neural groove
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Neural tube
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Neural groove forms into the neural tube
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Ventricles
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- Hollow spaces in the spinal cord and brain
- Brain has (4) - 1st & 2nd are lateral - 3rd & 4th are not |
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4 areas of the brain that develop from the Neural tube
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1 - Prosencephalon (forebrain)
2 - Mesencephalon (midbrain) 3 - Rhombencephalon (hindbrain) 4 - 4th ventricle |
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Develop from Neural Tube
- Prosencephalon |
- forebraine
- Dicencephalon - thalamus - hypothalamus - epithalamus - 3rd ventricle |
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Develop from Neural Tube
- Mesencephalon |
- Midbrain w/ tracts and nuclei
- corpora quadrigemina - visual reflex center (superior) - auditory reflex center (inferior) - nuclei that produce dopamine - called E. substantia nigra - cerebral perduncles |
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Develops from the Neural Tube
- Rhombencephalon |
- hindbrain
- 2 specfic areas - Pons - Medulla oblongata - Cerebellum |
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Develops from the Neural Tube
- Rhombencephalon - Pons |
- Tracts
-Conduction tracts between higher brain & spinal cord and between Cerebellum & motor cortex - Nuclei - apneustic area, inhaltion, and pneumatoxic, (inhibits inhalation) |
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Develops from the Neural Tube
- Rhombencephalon - Medulla Oblongata |
- Tracts
- Decussation of pyramids - which is the crossover for signals from left and right brain - Nuclei - controls heart rate, respiration, blood pressure, touch, and muscle positions |
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Develops from the Neural Tube
- Rhombencephalon - Cerebellum |
- has both white and grey matter
- 1/10th the brain mass, but 1/2 the total # of neurons - Tracts - arbor vitae tracks - Nuclei - give rise to axons to spinal cord and other brain centers - controls balance, coordination, posture, skilled movements - evaluates how well movements initiated by motor areas in the cerebrum are being carried out |
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Areas that develop from Neural Tube
- 4th ventricle |
Yup - it does
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Principle parts that develop from Neural tube
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Cerebrum - Know tracts and Nuclei
Dicephalon (and its parts) Cerebellum (and its parts) Brain Stem (and its parts) Areas that are continous with spinal cord... - pons, midbrian, medulla oblongata |
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Fissure
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Deep valley in brain
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Sulcus
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Shallow valley in brain
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Parts of Cerebrum
- Central Sulcus |
- Seperates frontal and parietal lobes
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Parts of Cerebrum
- Precentral gyrus |
- Before central sulcus (towards front of brain
- motor cortex |
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Parts of Cerebrum
- Postcentral gyrus |
- after central sulcus
- sensory cortex |
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Parts of Cerebrum
- Longitudinal Fissure |
- cuts brain into left and right cerebral hemispheres
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Parts of Cerebrum
- Parieto Occipto Sulcus |
- separetes the parietal lobes from the occipital lobes
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Parts of Cerebrum
- Lateral Sulcus |
- above temporal
- separates each temporal lobe from the lower portion of frontal and parietal lobes |
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Parts of Cerebrum
- Transverse fissure |
Separates cerebellum from cerebrum
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Parts of Cerebrum
- Cerebral Cortex |
- outer layer of grey matter in brain
- conscious behavior, - excutive control over nervous system - it is highly convuluted with dendrites, cell bodies, unmylennated axons - mostly designated for facial sensory and hand control |
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Parts of Cerebral Cortex
- (5) Hemispheres |
- Frontal (1)
- Parietal (1) - Temporal (2) - Occipital (1) - Insula (2 - hidden inside) |
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Parts of Cerebral Cortex
- Regions |
- Motory
- Sensory - Association |
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Parts of Cerebral Cortex
- Contralateral |
- means that info on the right goes to left brain, and info on left goes to right brain
- takes place at... - Dessucation of Pyramids in Medulla Oblongata |
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Parts of Cerebral Cortex
- Motor Region (4 areas) |
- Primary motor
- before central sulcus - called precentral gyrus - Premotor cortex - memory of how to do a motor skill (association) - Frontal eyefiled - muscle control of eye - cranial nerves III, IV, and VI - association - Broca's area - motor speech area - leftside of frontal lobe |
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Parts of Cerebral Cortex
- Sensory region (8 areas) |
- primary sensory
- Somatosensory Association Area - Primary Auditory Cortex - Auditory Association Area - Primary Visual Cortex - Visual Association Area - Gustatory Area - Olfactory Bulbs and Cortex |
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Parts of Cerebral Cortex
- Sensory region - Primary Sensory |
- Located in postcentral gyrus
- recieves info from receptors in skin/skeletal muscles - identifies body region being stimulated |
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Parts of Cerebral Cortex
- Sensory region - Somatosensory Assocation Area |
- Integrates and analyzes different sensory inputs
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Parts of Cerebral Cortex
- Sensory region - Primary Auditory Cortex |
- Located in Temporal lobe
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Parts of Cerebral Cortex
- Sensory region - Auditory Association Area |
- Perception
- due to memories, the information actually assocaited here is different for everyone |
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Parts of Cerebral Cortex
- Sensory region - Primary Visual Cortex |
- for reception
- located in the Occipital Lobe |
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Parts of Cerebral Cortex
- Sensory region - Visual Association Area |
Again - perception
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Parts of Cerebral Cortex
- Sensory region - Olfactory bulbs and Cortex |
- sense of smell - what more do ya need
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Parts of Cerebral Cortex
- Sensory region - Gustatory Area |
- Taste at the tip of tongue
- located at the bottom of central sulcus |
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Association
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Memory - the brains ability to associate information with other areas of the brain
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Association
- Personality |
Its your mood, how you act and what you do
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Association
- Prefrontal Cortex |
- MAIN AREA FOR ASSOCIATION
- most complicated region - processing to form personality - closely linked to limbic (emotions) - Intellect - Complex learning abilities |
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Association
- Left Brain |
- concrete information
- mathematical, logic, rational tasks, performing sequential processes |
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Association
- Right Brain |
- Abstract information
- Musical and artistic awareness |
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Association
- Language |
- Wernicke's area
- Located in left Brain - sounding out unfamiliar words - translates words into thoughts - areas on right brain add tonal inflection and emotional content |
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Association
- Visceral |
Interpretaion from viscera
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White Matter
- Characteristics (3) |
- Lines of communication for brain
- take things from one area of grey matter to another - Axons are mylennated - (4) types of tracts - Commissures - Association fibers - Projection fibers - Fornix |
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White Matter
- Types of tracts - Commissures |
- tracts run between the (2) cerebral hemispheres (left and right)
- Corpus Callosum - largest - it runs from Right to left and Left to Right between 2 ventricles |
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White Matter
- Types of tracts - Association Fibers |
- From one area of a hemisphere to another in the same hemisphere
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White Matter
- Types of tracts - Projection Fibers |
- at spinal cord, they fan out
- Shape is circle - Corona Radiata - looks like fiber optic flashlight |
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White Matter
- Types of tracts - Fornix |
- bandlike fiber tracts concerned with olfaction as well as limbic system functions
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Basal Nuclei
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- Cluster of cell bodies in Central Nervous System
- it is the inside area of grey matter |
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Basal Nuclei
- Characteristics |
- Regulates motor control
- cell bodies are packged together |
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Basal Nuclei
- Anterior |
- Lentiform and Caudate
- Corpus Striatum |
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Basal Nuclei
- posterior |
- Amygdaloid - functionality belongs to Limbic system (emotions)
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Basal Nuclei
- middle of brain |
Located here (no shit)
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Cortex means area is located in...
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Outer Grey matter
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Diencephalon
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- develops behind Basal Nuclei
- (3) Regions = Thalamus, Hypothalamus, Epithalamus |
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Diencephalon
- Thalamus |
- GATEWAY TO CORTEX
- acts as a major sensory relay and integration center of brain |
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Diencephalon
- Epithalamus |
- forms roof of 3rd Ventricle
- Pineal gland = Secretes malatonin involved with sleep-wake cycles and moods - Choroid plexus = produces cerebral spinal fluid |
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Diencephalon
- Hypothalamus |
- Neural clearing house for autonomic and emotional response
- Visceral control - Autonomic control = respiration rate, emotions, sleep, hunger, thirst, temperature reg, sex drive, sleep/wake cycle - ends in Infundibulum = connects to pituitary gland = releases hormones |
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Limbic System
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The Emotional Brain
- its where emotions live |
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Limbic System
- Fornix |
- Links limbic system regions together
- White matter |
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Limbic System
- 2 important parts to emotions |
Amygdala = recognizes fearful/angry faces, assesses danger, and creates fear response
Cingulate Gyrus = helps w/ conflict resolution, expressing emotions through gestures |
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Limbic System
- Amygdala and Hippocampus |
- together equal LONGTERM MEMORY
- changes new info into longterm memories |
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Limbic System
- special interaction with prefrontal cortex |
there is a special relationship between feelings and thoughts
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Reticular Activating System
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Activates Cerebrum to wake up brain (and person)
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Meninges
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covering of the brain & Spinal cord
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Meninges order
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from outside in...
Skull Duramater periosteal (not in Spinal cord) Duramater meningeal Arachnoid mater Subarachoid space Pia mater |
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Meninges
- Skull |
The outermost covering of the brain, it is wrapped in Periosteum
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Meninges
- Dura Mater |
It is rough and leathery w/ 2 layers
- Periosteal =(not in spinal cord - Meningeal = true external covering of brain - Meningeal AKA dural sheath of spinal cord |
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Meninges
- Arachoid Mater |
Located as the middle Mater
- loose covering not dipping into sulci - it is made of fine fibers and is elastic |
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Meninges
- Subarachoid Space |
- Weblike extensions attach Arachoid Mater to Pia Mater
- Contains Cerebral Spinal Fluid and the largest blood vessels serving the brain - Arachoid Villi = Absorbs Cerebral spinal fluid into blood stream |
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Meninges
- Pia Mater |
- Delicate, very sticky connective tissue
- many tiny blood vessels - only layer to cling tightly to brain |
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Blood Barrier
-use and exceptions |
- capillary endothelial cells joined by tight junctions, which is the least permeable in the body
- exceptions are the avomiting center of brain stem and hypothalamus - not yet developed in new borns - so be careful... |
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Type of Stimulus
- Mechanoreceptors |
- mechanical force such as touch, pressure, vibration, stretch, itch
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Type of Stimulus
- Thermoreceptors |
- temperature changes
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Type of Stimulus
- Photoreceptors |
- light energy
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Type of Stimulus
- Chemoreceptors |
- chemicals in solution/taste, smell
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Type of Stimulus
- nociceptors |
- stimuli that results in pain
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Type of Stimulus
- proprioceptors |
- location of stimulus
- advises brain of body movements by monitoring how much organ is stretched |
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Stucture of Nerve
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Nerve is a bundle of neuron fibers
- Neuron is a nerve cell - most nerves are mixed (both sensory and motor - special coverings of neurons |
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Structure of Neuron
- coverings |
Myelin - covers Axon
Endoneuron - surrounds myelin perineuron- surrounds fascicle (group of axons) Epineuron - surrounds group of fascicles and blood vessels |
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Cranial Nerves
- I |
Olfactory
- purely sensory - smell |
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Cranial Nerves
- II |
Optic
- purely sensory - vision |
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Cranial Nerves
- III |
Oculomotor
- purely motor - "eye mover" 4/6 extrinsic eye muscles - Parasympathetic |
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Cranial Nerves
- IV |
Trochlear
- purely motor - moves one muscle of eye |
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Cranial Nerves
- V |
Trigeminal
- Mixed (both sensory and motor) - has 3 divisions = Opthalmic, maxillary, and Mandibular - dentist numbs maxillary and mandibular - lets you feel teeth |
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Cranial Nerves
- VI |
Abducens
- Purely Motor - moves one extrinsic muscle of eye |
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Cranial Nerves
- VII |
Facial
- largest Cranial nerve - Major Cranial nerve for face - laughing, smiling, and anterior 2/3 of tongue (sweet & salty) - Parasympathetic |
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Cranial Nerves
- VIII |
Vestibular Cochlear
- Purely sensory - hearing |
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Cranial Nerves
- IX |
Glossopharyngeal
- Mixed (both sensory & motor) - swallowing & latter 1/3 of tongue (bitter & sour) - Parasympathetic |
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Cranial Nerves
- X |
Vagus
- Mixed (both sensory & motor) - only cranial nerve to extend beyond head and neck - Parasympathetic |
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Cranial Nerves
- XI |
Accessory
- Mixed (both sensory & motor) - has 2 roots = cranial root from medulla oblongata, spinal root from c1-c5 |
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Cranial Nerves
- XII |
Hypoglossal
- Mixed (both sensory and motor) - swallowing and speech |
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Levels of Motor Control
- (list them) |
From lowest to high
- segmental - projection - precommand |
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Levels of Motor Control
- Segmental |
- lowest level
- Spinal cord circuits |
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Levels of Motor Control
- Projection |
- middle level
- upper motor neurons of motor cortex and brain stem |
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Levels of Motor Control
- Precommand |
- highest level
- cerebellum and nuclei |
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Somatic Nerves
|
Motor neuron cell bodies in CNS and axons extend in spinal nerves to skeletal muscles
- thick and heavily myelinated - lack ganglia |
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Spinal Cord
- beginning and ending |
- Continous from 4th ventricle
- has a central canal - oval shaped - goes through Magnum foramen - ends at L1 or L2 vertebrae |
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Spinal Cord
- Butterfly shape (meaning) - Horns |
- White matter outside
- grey matter inside - Posterior Horns = dorsal = sensory - Anterior Horns = ventral = motor |
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Spinal Cord
- sensory tracts - 1st 2nd 3rd order |
- Sensory tracts ascend
- 1st order = dorsal root ganglion - 2nd order = dorsal horn - 3rd order = thalamus |
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Spinal Cord
- motor tracts - upper motor neurons - lower motor neurons |
- motor tracts descend
- upper motor neurons = go from motor cortex to motor nuclei - lower motor neurons go from anterior horns to skeletal muscles |
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Spinal Cord
- Reflex centers |
Interneurons are the reflex centers
- involuntary and rapid |
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Spinal Cord
- Reflex centers order of operations |
Receptor - Sensory Neuron - Integration Center - Motor Neuron - Effector
*** just like that*** |
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Spinal Cord
- other names for Integration center |
Integration center - AKA - Interneuron - AKA - Association Center
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Spinal Cord
- Cauda Equina |
"Horse's tail"
- collection of nerve roots at inferior end that fan out |
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Spinal Cord
- Conus Medullaris |
- end of cord in tapering cone shaped struture.
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Spinal Cord
- Spinal Tap location |
Below spinal cord, below L3 vertebrae
- b/c spinal cord ends at L1 or L2 |
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Spinal Cord
- Filum terminale |
Pia mater fastens cord in place
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Spinal Nerves
- Total breakdown |
31 total spinal nerves
- 8 cervical - 12 thoracic - 5 lumbar - 5 sacral - 1 coccygeal |
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Spinal Nerves
- length |
They be short
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Spinal Nerves
- ganglia |
Group of cell bodies outside CNS
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Spinal Nerves
- Dorsal root |
SENSORY - AFFERENT
- cell bodies lie outside spinal cord in dorsal root ganglion |
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Spinal Nerves
- Ventral root |
MOTOR - EFFERENT
- cell bodies lie in anterior horn |
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Spinal Nerves
- Rami |
Spinal nerve branches into dorsal and ventral Rami
- Mixed (both Sensory & motor) |
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Spinal Nerves
- Plexus |
Formed from ventral Rami
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Spinal Nerves
- Plexus = Cervical |
- C1-C4
- Phrenic nerve is most important = sensory and motor nerves for diaphram |
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Spinal Nerves
- Plexus = Brachial |
- C5-C8 + T1
- it is entire nerve supply to upper extremities, neck and shoulder muscles - Ulna = funny bone = nerve rests against medial epicondoyle - Radial = largest branch |
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Spinal Nerves
- Plexus = Lumbar |
- L1-L4
- abdominal wall, external genitals, part of lower extremities - Femoral = Largest nerve in body = goes through thigh, buttocks,perneum, and lower extremities |
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Spinal Nerves
- Plexus = Sacral |
- L4-L5 + S1-S4
- Sciatic nerve = thickest and longest in body - Pudendal nerve = causes erection, involuntary urination |
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Spinal Nerves
- Dermatones + one exception |
area of skin innervated by the cutaneous branches of a single spinal nerve
- C1 is the only spinal nerve that does not innervate a dermatone |
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Spinal Nerves
- Hilton's law |
Same nerve will effect skin, muscle and joint in the same localized area
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Spinal Nerves
- Intercostal Nerves |
come from thoracic vertebrae
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Autonomic Nervous System
- Traits |
- Mixed (both sensory and motor)
- Part of the periphreal nervous system - Effectors are smooth muscle, cardia, and glands - normally involuntary - has 2 neuron chain consisting of cell body of preganglionic neuron in brain or spinal cord preganglionic axon and cell body of ganglionc neuron outside CNS postganglionic axon |
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(2) divisions of ANS
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Sympathetic system
Parasympathetic system |
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Sympathetic system
- diff from Para |
- accelerates body
- arises from T1-T2 - preganglionic fibers are short - postganglionic fibers are long - Uses ACh for preganglion, Norepinephrine for Postganglion -Ganglion are far away from organ, but close to CNS - FIGHT OR FLIGHT |
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Parasympathetic System
- diff from Sympathetic |
- Brakes
- arises from III, VII, IX, X, S2-S4 - preganglionic fibers are long - postganglionic fibers are short - Ganglion are near organs, away from CNS - used for resting and digesting |
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Sympathetic system
- characteristics |
- Rage, Terror, fear
- Dilates pupil by contracting radial muscle to open eye - relaxes bladder muscle, contracts anal sphincter - increases heart rate - decreases digestion rate - increases blood pressure, affects kidneys with renin - relaxes bonchiole to breath more - liver changes glycogen to glucose for energy |
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Parasympathetic system
- characteristics |
- slows you down
- maintains homeostasis - contracts pupil by contracting circular muscle - contracts bladder muscle and relaxes anal sphincter - decreases heart rate - increases digestion rate - constricts bonchioles |
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Similarities
- Sympathetic and parasympathetic systems |
- serve most of the same organs
- generally cause opposing effects - all preganlions release ACh |