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61 Cards in this Set

  • Front
  • Back
Basic functional & structural unit of life
Cell
Principle of complementarity
Biochemical activity of cell reflects the operation of its organelles 3 major regions of a cell
3 components of a cell
Nucleus, cytoplasm & plasma membrane
Functions of plasma membrane
1. Encloses cell contents
2. Mediates exchanges with extracellular environment
3. Plays role in cellular communication
3 components of plasma membrane
Phospholipids
Cholesterol
Glycolipids
Transmembrane proteins
Extend thru plasma membrane usually on both sides
Peripheral proteins
Attach to integral proteins & are outside the plasma membrane
Functions of plasma membrane proteins
Enzymes
Receptors
Mediate membrane transport
Cell junctions
Join cells together & aid or inhibit movement of molecules between cells
Tight junctions
Virtually impenetrable
Desmosomes
Mechanically couple cells
Gap junctions
Allow joined cells to communicate
Passive processes
Diffusion
Facilitated diffusion
Osmosis
Diffusion
Movement of molecules down concentration gradient
Facilitated diffusion
Movement of certain solutes across membrane by either binding with carrier protein or by going thru a membrane channel
Osmosis
Diffusion of water thru plasma membrane thru aquaporons
Hypertonic
Solutions that cause net loss of water
Hypotonic
Cause a net gain of water
Isotonic
Cause neithet gain nor loss of water
Active transport depends on what 2 things
Carrier proteins & atp
Primary active transport
Such as na k pump
Atp directly provides energy
Secondary active transport
Energy of ion gradient caused by an active transport process is ised to transport substances passively
Symport
Cotransported substances move in same direction
Antiport
Cotransported substances move in opposite directions
3 types of vesicular transport
Endocytosis
Exocytosis
Transcytosis
Phagocytosis
Process by which relatively large particles are brought into cell
Pinocytosis
Process by which dissolved molecules are brought into cell
Receptor-mediated endocytosis
Selective
Engulfed molecules attach to receptors on cells before endocytosis occurs
Exocytosis
Uses SNARES
ejects substances from cell
Most endo- & transcytosis is mediated by:
Clthrin-coated vesicles
Resting membrane potential is generated by what two things?
Concentration gradient of ions
Differential permeability of plasma membrane
Where is sodium found in high & low concentrations in relation to the cell
High extracellular concentration
Low intracellular concentration
Where is K in high & low concentration in relation to the cell?
High intracellular
Low extracellular
Negative membrane potential is established how?
Movement of K out of cell equals movement of K into cell
3 basic components of cytoplasm
Cytosol
Inclusions (nonliving nutrient stores, pigment granules, crystals etc)
Organelles
Mitochondria
Site of atp formation
Ribosome
Site of protein synthesis
Rough ER
Protein modification
Smooth ER
Synthesizes lipids & steroids
Golgi apparatus
Packages proteins
Lysosomes
Intracellular digestion
Peroxosomes
Destroys free radicals & toxins
3 components of cytoskeleton
Microtubules
Intermediate filaments
Microfilaments
Microtubules
Organize cytoskeleton & important in intracellular transport
Microfilaments
Important in cell motility
Intermediate filaments
Help cells resist mechanical stress
Organize the mitotic spindlev& are the bases of cilia & flagella
Centrioles
Microvilli
Extensions of the plasma membrane that increase surface area
Control center of cell
Nucleus
Nucleoli
Nuclear site of ribosomal subunit synthesis
Chromatin
Slender threads containing histone proteins & dna
Interphase
Nondividing phase of cell cycle
G1, growth
S dna replicates
G2 ginal prepps
Semiconservative replication of dna
Produces 2 dna molecules each formed with one old and one new strand
4 phases of mitosis
Prophase
Metaphase
Anaphase
Telophase
Cytokenesis
Divides cytoplasmic mass into two parts
Mrna
Messenger rna
Carry instructions for making polypeptide chain to ribosome
Trna
Transfer rna
Binds to a codon on mrna strand specifying its amino acids
Rrna
Ribosomal rna
Forms part of protein synthesis site
Transcription
Done by mrna
Translation
By trna
Apoptosis
Cell suicide