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61 Cards in this Set
- Front
- Back
Basic functional & structural unit of life
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Cell
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Principle of complementarity
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Biochemical activity of cell reflects the operation of its organelles 3 major regions of a cell
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3 components of a cell
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Nucleus, cytoplasm & plasma membrane
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Functions of plasma membrane
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1. Encloses cell contents
2. Mediates exchanges with extracellular environment 3. Plays role in cellular communication |
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3 components of plasma membrane
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Phospholipids
Cholesterol Glycolipids |
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Transmembrane proteins
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Extend thru plasma membrane usually on both sides
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Peripheral proteins
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Attach to integral proteins & are outside the plasma membrane
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Functions of plasma membrane proteins
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Enzymes
Receptors Mediate membrane transport |
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Cell junctions
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Join cells together & aid or inhibit movement of molecules between cells
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Tight junctions
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Virtually impenetrable
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Desmosomes
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Mechanically couple cells
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Gap junctions
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Allow joined cells to communicate
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Passive processes
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Diffusion
Facilitated diffusion Osmosis |
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Diffusion
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Movement of molecules down concentration gradient
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Facilitated diffusion
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Movement of certain solutes across membrane by either binding with carrier protein or by going thru a membrane channel
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Osmosis
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Diffusion of water thru plasma membrane thru aquaporons
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Hypertonic
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Solutions that cause net loss of water
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Hypotonic
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Cause a net gain of water
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Isotonic
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Cause neithet gain nor loss of water
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Active transport depends on what 2 things
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Carrier proteins & atp
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Primary active transport
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Such as na k pump
Atp directly provides energy |
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Secondary active transport
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Energy of ion gradient caused by an active transport process is ised to transport substances passively
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Symport
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Cotransported substances move in same direction
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Antiport
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Cotransported substances move in opposite directions
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3 types of vesicular transport
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Endocytosis
Exocytosis Transcytosis |
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Phagocytosis
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Process by which relatively large particles are brought into cell
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Pinocytosis
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Process by which dissolved molecules are brought into cell
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Receptor-mediated endocytosis
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Selective
Engulfed molecules attach to receptors on cells before endocytosis occurs |
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Exocytosis
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Uses SNARES
ejects substances from cell |
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Most endo- & transcytosis is mediated by:
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Clthrin-coated vesicles
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Resting membrane potential is generated by what two things?
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Concentration gradient of ions
Differential permeability of plasma membrane |
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Where is sodium found in high & low concentrations in relation to the cell
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High extracellular concentration
Low intracellular concentration |
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Where is K in high & low concentration in relation to the cell?
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High intracellular
Low extracellular |
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Negative membrane potential is established how?
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Movement of K out of cell equals movement of K into cell
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3 basic components of cytoplasm
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Cytosol
Inclusions (nonliving nutrient stores, pigment granules, crystals etc) Organelles |
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Mitochondria
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Site of atp formation
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Ribosome
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Site of protein synthesis
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Rough ER
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Protein modification
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Smooth ER
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Synthesizes lipids & steroids
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Golgi apparatus
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Packages proteins
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Lysosomes
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Intracellular digestion
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Peroxosomes
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Destroys free radicals & toxins
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3 components of cytoskeleton
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Microtubules
Intermediate filaments Microfilaments |
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Microtubules
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Organize cytoskeleton & important in intracellular transport
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Microfilaments
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Important in cell motility
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Intermediate filaments
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Help cells resist mechanical stress
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Organize the mitotic spindlev& are the bases of cilia & flagella
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Centrioles
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Microvilli
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Extensions of the plasma membrane that increase surface area
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Control center of cell
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Nucleus
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Nucleoli
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Nuclear site of ribosomal subunit synthesis
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Chromatin
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Slender threads containing histone proteins & dna
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Interphase
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Nondividing phase of cell cycle
G1, growth S dna replicates G2 ginal prepps |
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Semiconservative replication of dna
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Produces 2 dna molecules each formed with one old and one new strand
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4 phases of mitosis
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Prophase
Metaphase Anaphase Telophase |
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Cytokenesis
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Divides cytoplasmic mass into two parts
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Mrna
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Messenger rna
Carry instructions for making polypeptide chain to ribosome |
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Trna
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Transfer rna
Binds to a codon on mrna strand specifying its amino acids |
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Rrna
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Ribosomal rna
Forms part of protein synthesis site |
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Transcription
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Done by mrna
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Translation
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By trna
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Apoptosis
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Cell suicide
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