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59 Cards in this Set
- Front
- Back
Motor unit
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A single somatic motor neuron & all the muscle fibers it stimulates
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Muscular atrophy
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Wasting away of muscle due to lack of use
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Fibrosis
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The replacement of skeletal muscle fibers with scar tissue
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Somatic motor neurons
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Provide the nerve impulses that stimulate skeletal muscle to contract
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4 properties of muscle tissue
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Electrical excitability
Contractility Extensibility Elasticity |
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Myofibrils
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The contractile elements of skeletal muscle
Composed of 3 types of proteins: contractile, regulatory and structural |
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Excitability
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The ability of muscle cells to respond to stimuli and produce electrical signals
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Sequence of events resulting in muscle contraction
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1. Nerve impulse
2. Release of acetylcholine 3.Muscle action potential 4. Release calcium ions from sarcoplasmic reticulum 5. Calcium ion binding to troponin 6. Power stroke, actin & myosin binding & release |
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Tintin
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Structural protein, connects z disc to m line of the sarcomere, stabilize position.
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Sacromere
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Basic functional units of myofibril, in muscle fiber
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Z discs
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Narrow plate-shaped regions of dense protein that separate one sarcomere from the next
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M line
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Region in center of the H zone that contain proteins that hold thick filaments together at the center of the sarcomere
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Components of Sarcomere
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z discs, a band, I band, H zone, M line
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A band
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Dark middle part of sarcomere, extends entire length of filament
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I band
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Lighter less dense area of sarcomere, no thick filaments
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H zone
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Narrow region in center of each A band, contains thick filaments
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Myosin
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Contractile motor protein
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Tropomyosin
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Regulatory protein that blocks myosin-binding sites
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Actin
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Contracile protein that contains myosin-binding sites
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Calsequestrin
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Calcium-binding protein
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Sources of ATP for muscle contraction
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Creatine phosphate
Glycolysis Anaerobic cellular respiration Aerobic cellular respiration |
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Endomysium
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Sheath of areolar connective tissue that wraps around individual skeletal muscle fibers
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Perimysium
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Dense irregular connective tissue that separates a muscle into groups of individual muscle fibers
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Fascicles
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Bundles of muscle fibers
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Epimysium
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Outermost connective tissue layer, encircles entire skeletal muscle
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Fascia
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Dense irregular connective tisuuse, lines body wall, holds functional muscle units together.
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Tendon
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Cord of dense regular connective tissue, attaches muscle of periostium of bone
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Muscle fiber
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Muscle cell
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Aponeurosis
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Connective tissue elements, extend as broad flat layer
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Tendon sheath
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2 layer tube of fibrous connective tissue enclosing certain tendons
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Neuromusclar junction
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Synapse btwn a motor neuron and a muscle fiber
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Transverse tubules
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Invaginations of the sarcolemma from the surface toward the center of the muscle fiber
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Satellite cells
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Myoblasts that persist in mature skeletal tissue
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Sarcolemma
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Plasma membrane of a muscle fiber
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Myoglobin
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Oxygen-binding protein found only in muscle fibers
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Sarcoplasmic reticulum
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Ca2+ storing tubular system similar to smooth ER
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Sarcomere
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Contracting unit of skeletal muscle fiber
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Sarcoplasm
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Cytoplasm of muscle fiber
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Skeletal muscle
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Striated, no autorhythmicity, uses satellite cells to repair damages fiber
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Cardiac muscle
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Fibers joined by intercalated discs, striated, has extended contraction due to prolonged calcium delivery, uses troponin as regulatory protein, can be autorhythmic
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Smooth muscle
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No arranged in sarcomeres, contraction begins slowly but lasts long time, uses pericytes to repair, can be autorhythmic, uses calmodulin as regulatory protein
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Stress-relaxation response
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Smooth muscle action that allows the fibers to maintain their contractile function even when stretched
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Twitch contraction
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Brief contraction of all the muscle fibers in a motor unit in response to a single action potential in its motor neuron
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Fused tetanus
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Sustained contraction, no relaxation btwn stimuli
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Wave summation
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Larger contraction resulting from stimuli arriving a different times
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Motor unit recruitment
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Process of increasing the # of activated motor units
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Concentric isotonic contraction
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Contraction in which the muscle shortens
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Muscle fatigue
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Inability of muscle to maintain its strength of contraction during prolonged activity
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Unfused tetanus
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Sustained but wavering contraction with partial relaxation btwn stimuli
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Muscle tone
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Produced by continual involuntary activation of a small # of skeletal motor units, results in firmness
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Isometric contraction
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Contraction where muscle tension is generated without shortening of muscle
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Recovery oxygen uptake
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Amount of O2 needed to restore the body's metabolic conditions back to resting levels after exercise
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Eccentric isotonic contraction
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Contraction in which a muscle lengthens
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Perimysium bundles...
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Groups of muscle fibers into fasicles
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Sarcoplasmic Reticulum releases..
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Calcium ions to trigger muscle contractions
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Sarcomeres are separated by?
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Z discs
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What bands/zones disappear during muscle contraction?
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I and H
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If ATP were not available what would happen?
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Crossbridges would not detach from actin, muscle would remain rigid
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Motor end plate
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Part of sarcolemma that contains acetylcholine receptors
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