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26 Cards in this Set
- Front
- Back
four classifications of bones?
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Long bones
Short bones Flat bones Irregular bones |
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Function of bones?
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Support
Protection Movement Mineral storage Blood cell formation (hematopoiesis) |
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Structure of long bones
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Periosteum - double layered protection membrane. Outer fibrous layer is dense irregular connective tissue. Inner osterogenic layer is composed of osteoblast/clast
Endosteum - delicate membrane covering internal surfaces of bone |
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Structure of short, irregular, and flat bones?
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Thin plates of Periosteum covered compact bone on outside with endosteum covered spongy bone inside
No diaphysis or epiphyses Contains bone marrow between trabeculae |
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Location of red marrow
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Infants - in medullary cavity and all spongy bone
Adults - in spongy bone of flat bones, and head of femur and humerus |
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Organic materials of bone
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Osteoblasts - bone-forming cells
Osteocytes - mature bone cells Osteoclasts - large cells that reabsorb or break down bone matrix Osteoid - unmineralized bone matrix composed of proteoglycans, glycoprotens, and collagen |
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Inorganic materials of bone?
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Hydroxypatites (mineral salts)
Mainly calcium phosphates Responsible for bone hardness and compressional strength |
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Osteogenesis and ossification
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Process of bone tissue formation
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Intramembranous ossification?
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bone develops from a fibrous membrane
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Endochondral ossification?
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bones form by replacing hyaline cartilage
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Long bone growth and remodeling
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Growth in length - cartilage continually grows and is replaced by bone
Remodeling - bone is reabsorbed and added by appositional growth |
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Hormonal regulation of bone growth during youth
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epiphyseal plate activity is stimulated by growth hormone.
testosterone and estrogen: initially promote growth spurts cause masculination and feminization of skeleton later induce epiphyseal plate closure, ending longitude bone growth |
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bone deposition
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Occurs when bone is injured or added strength is needed
requires a diet rich in protein, vitamins C D A, calcium, phosphorus, magnesium, and manganese alkaline phosphates are essential for mineralization of bone |
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controls of bone remodeling
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Hormonal mechanism maintains calcium homeostasis in blood
mechanical and gravitational forces acting on skeleton |
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Calcium is necessary for -
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Transmission of nerve impulses
Muscle contraction Blood coagulation Secretion by glands and nerve s Cell division |
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Osteomacia
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Bones are inadequately mineralized causing softened, and weakened bones
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Rickets
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bones of children are inadequately mineralized causing softened and weakened bones
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Osteoporosis
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Group of diseases in which bone reabsorption outpaces bone desposit. causes brittle bones.
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Vitamins C, A, K, and B12
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C is for collagen synthesis
A stimulates osteoblast activity K and B12 help synthesize bone proteins |
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growth hormone and thyroxine
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stimulates bone growth
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Estrogens and androgens
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stimulate osteoblasts
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Calcitonin and parathyroid hormone
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regulate calcium and phosphate levels
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skeletal cartilage
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no blood vessels or nerves
surrounded by perichondrium (dense irregular connective tissue) three types - hyaline, elastic, fibrocartilage |
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hyaline cartilage
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support, flexibility, and resilience
present as articular cartilage covering long bone ends |
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elastic cartilage
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similar to hyaline but contains elastic fibers
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fibrocartilage
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highly compressed with great tensile strength
contains collagen fibers |