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178 Cards in this Set

  • Front
  • Back
Endocrine system
consists of a group of glands that produces regulatory chemicals called hormones.
The Endrocrine and Nervous System:
Work together to control and coordinate all other systems.
Hormones
are chemical messengers that have specidic regulatory effects on certain cells or organs.
Hormones from the endocrine glands:
are released directly into the bloodstream, which carries them to all parts of the body. They regulate growth, metabolism, reproduction, and behavior.
Hormones that effect tissues:
Examples -
Growth hormone, thyroid hormone, and insulin.
Thyroid Stimulating Hormone (TSH)
a hormone that only EFFECTS one specific tissue, one pituitary homone, TSH, acts only on the thyroid gland.
Andrnocorticotropic Hormone (ACTH):
Stimulates ONLY the outer portion of the adrenal gland.
Target Tissue
Is the specific tissue acted on by each hormone.
Receptors
cells that make up these tissue (target tissues), have receptors in the plasma membrane or in the cytoplasm to which the hormone attaches.
Hormone Chemistry
Chemically hormones fall into 2 main categories, the Amino Acid Compounds, and Steroids.
Amino Acid Compounds:
These hormones are proteins or related compounds also made of amino acids. All hormones except those of the adrenal cortex and the sex glands fall into this category.
Steroids:
These hormones are types of lipids derived from the steroid cholesterol. Steroid hormones are produced by the adrenal cortex and the sex glands, steroid hormones can be recognized by the -one, as in progesterone, testosterone.
Hormone Regulation: (Negitive Feedback): Most commonly used
In negitive feedback, the hormone itself, or the result of its action; controls futher homone secretion. When the target tissue becomes too active, there is a negative feedback effect on the endrocine gland, which then decreases its secretory action.
Hormome Regulation; (Postive Feedback): Less commonly used:
In this case, response to a hormone promotes further hormone release. An example of that would be the action of oxytocin during labor, and the release of hormones in the menstraul cycle.
Hypersecretion
oversecretion
hyposecretion
undersecretion
Where the Pituitary gland is located?
In a saddlelike depression of the sphenoid bone, just posterior to the point where the optic nerves cross.
Infundibulum
A stalk in the brain where the pituitary gland connects with the hypothalmus.
Hypophysis
The pituitary gland is also called this.
Anterior and Posterior Lobe
The Pituitary gland is divided into 2 parts.
Master Gland
The pituitary is often called this because it releases hormones that affect the working of other glands, such as the thyroid, gonads (ovaries and testes), and Adrenal glands.
-tropin (thytrotropin)
Hormones that stimulate other glands may be recognized by the ending -tropin, which means (acting on the thyroid gland).
Hypothalamus
The pituitary itself is controlled by this gland, which sends secrections and nerve impulses to the pititurary through the infundibulum.
Control of the pituitary: (Anterior Pituitary)
The hormones produced in the anterior pituitary are not released until a chemical messangers called releasing hormones arrive from the hypothalamus. They travel by way of a special type of circulatory pathway called a portal system.
Portal system
how hormones travel to be released on the Anterior side of the pituitary gland. By this circulatory detour, some of the blood that leaves the hypothalmus travels to capillaries in the anterior pituitary before returing to the heart.
Abbreviation RH
is added to the name of the hormone stimulated by the hypothalmaic releasing hormones only on the anterior side of the pituitary, for example, GHRH meaning, growth hormone releasing hormone.
Inhibiting hormones (IH)
2 anterior pituitary hormones are also regulated by inhibiting hormones from the hypothalmus. Inhibiting hormones suppress both the growth hormone which stimulates growth and metabolism, and Prolactin which stimulates milk production in the mammary glands, these inhibiting glands are abbreviated (GHIH) growth hormone-inhibiting hormone, (PIH) Prolactin-inhibiting hormone).
Gonadotropins
FSH (follicle stimulating hormone), LH (Luteinizing hormone), are classified as gonadotropins, there hormone that act on the gonads to regulate growth, development, and function of the reproductive systems in both male and female.
Gigantism
a tumor in childhood that will force you to grow to be abnormally tall stature.
Acromegaly
this is when the GH producing cells become overacted in the adult. Which causes a type of gigantism in adults.
Thyroid
located in the neck, is the largest of the endocrine glands. The thyroid has 2 roughly oval lateral lobes on either side of the laryx (voice box) connected by a narrow band called the (Ishmus). A connective tissue capsule encloses the entire gland.
Thyroxine (thyroid hormone)
Is one of the thyroid glands that regulate metabolism. Thyroxine is symbolized as T4 based on the number of iodine atoms in each molecule
Thiiodothyronine (thyroid hormone)
This hormone contains 3 atoms of iodine. So this hormone is called T3. These hormones function to increase the rate of metabolism and protein metabolism.
Iodine deficiency
The thyroid needs an adequate supply of iodine to produce hormones. The deficiency is rare now due to the wide spread availability of this mineral in iodized salt, veggies, seafood, dairy products, and procedded foods.
Calcitonin (thyoid hormone)
active in calcium metabolism. Calcionin lowers the amount of calcuim in circulating in the blood by promoting the deposit of calcium in bone tissue.
Goiter
Is an enlargement of the thyroid gland, which may or may not be associtate with overproduction of hormone.
Simple Goiter
is the uniform overgrowth of the thyroid gland, with a smooth surface appearance.
Andemomatous or nodular goiter
is an irregular appearing goiter accompanied by a turmor formation.
Hypothyroidism
shows up as two characteristic states related to age:
Infantile hypothyrodism also known as cretinism
is a condition resulting from hypothyroidism in infants and children. The usual cause is a failure of the thyroid gland to form. The infant suffers from mental development and physical growth, early continuous treatment with replacement hormone can alter the outlook. By state law, all newborns are tested for this in the USA.
Myxedema (hypothyroidism)
results from thyroid atrophy, (waisting) in adults. The patient becomes sluggish both mentally and physically and often feels cold. Because thyroid hormone can be administered orally, the patient with myxedema can regain health easily, although treatment must be maintained throught life.
Hyperthyroidism
Is the opposite of hypothyroidism, overactivity of the thyroid gland with excessive secreation of hormone.
Grave Disease
A common form of hyperthyrodism, which is characterized by a goiter, a strained apperarance of the face, intense nervousness, weight loss, a rapid pulse, sweating, tremors, and abnormally quick metabolism. Another syptom that is outstanding, is the bulding of the eyes, (protrusion).
ExophtThalmos (hyperthroidism)
This is known as prtrusion (bulging) of the eyes. This is caused by swelling of the tissue behind the eyes.
Treatment of Hyperthroidism
suppresion of hormone production with medication.
Destruction of thyroid tissue with radioactive iodine.
Surgical removal of part of the thyroid gland.
Thyroid Storm
An exaggerated form of hyperthyroidism with a sudden onset. Untreated, it is usually fatal, most affected people can be saved.
Thyroiditis
Is the general term meaning inflammation of the thyroid.
Hashimoto Disease
Is an autoimmune thyroiditis that may be hereditary and my also involve excess intake of iodine.
The disease results in enlargemtn of the thyroid (goiter) and hypothyroidism. It is treated with thyroid hormone replacement and, in some cases surgery.
Parathyoid Glands
Are embedding in the posterior capsule of the thyroid. The secretions from these glands promotes calcium release from bone tissue, thus increasing the amount of calcium circulating in the bloodstream. PTH also causes the kidney to conserve calcium, low PTH, as may be caused by removal of the parathyroids, results in muscle spasms (tentany).
Calcitriol - technically called dihydroxycholecalciferol
One other hormone is needed for calcium balance in addition to calcitonin and PTH is Calcitriol.
This is the active form of Vit. D in the liver and the kidney. It increases intestinal absorption of calcium to raise blood calcium levels.
Calcitonin, PTH, and Calciriol work together to regulate the amount of calcium in the blood and provide calcium for bone maintaince and other functions.
Tetany
Spasms due to a low concentration of blood calcium.
Adrenal Glands
Are 2 small glands located atop the kidneys. Each edrenal gland has 2 parts that act as separate glands.
The inner layer is called the medulla and the outer layer is called the cortex.
Medulla
Is the inner layer of the adrenal glands.
Cortex
Is the outer layer of the adrenal glands.
Epinephrine also called Adrenaline
comes from the adrenal glands.
This is the principle hormone produced by the medulla.
Norepinephrine (noradrenaline)
Is closely related chemically and is similar in its actions to Epinephine. These 2 hormones are referred to as the "flight or fight" hormones.
Because of their affects during emergency times
When released from nerve endings instead of being released directly into the blood stream, they function as neurotransmitters.
Some of the effects:
Stimulation - of the involuntary muscle in the walls of the arterioles, causing these muscles to contract and blood pressure to rise accordingly.
Conversion: of glycogen stored in the liver into glucose. The gluscose pours into the blood and travels throughout the body, allowing the voluntary muscles and other tissues to do the extraodinary amount of work.
Increase heart rate
Increase in the metabolic rate of body cells.
Dilation of the bronchioles, through relaxation of the smooth muscle of their walls.
Adrenal Cortex -
3 main groups of hormones secreted by the adrenal cortex:
Clucocorticoids
Mineralocorticoids
Sex Hormones.
Glucocorticoids (adrenal cortex)
Maintain the carbs. reserve of the body by stimulating the liver to convert amino acids into glucose (sugar) instead of proteing. It also has the ability to supress inflammatory response and are often administed as medication for this purpose. The major hormone of this group is the CORTISOL, which is also called hydrocortisone.
Mineralocorticoids (adrenal cortex)
Are important in the regulation of electrolyte balance. They control sodium reabsorption and potassium secretion by the kidney tubules. The major hormone from this group is ALDOSTERONE.
Sex Hormones (Adrenal cortex)
are secreted in small amounts having little effert on the body.
Disorders of the Adrenal Cortex:
Addisons Disease, and Cushing syndrome,
Addison's Disease
A disease characterized chiefly by muscle atrophy (loss of tissue), weakenss, skin pigmentation, and disturbances in salt and water balance.
Cushing Disease
Hypersection of cortisol results in a condition called cushing disease, the syptoms in which include obesity with a moon face, thin skin that bruises easy, muslce weakness, bone loss and elevated blood sugar.
Pancreas
small groups of specialized cells called (ISLETS), also known as (ISLETS OF LANGERHANS). These cells make up the endrocrine portion of the pancreas.
Insulin (most important)
The most important hormone secreted by the Islets is Insulin. Insulin is active in the transport of glucose across plasm membrane, thus increasing cellular glucose uptake.
Glucagon (hormone produced by islets)
Works with insulin to regulate blood sugar levels. Glucagon causes liver to release stored glucose into the bloodstream. Glucagon also increases the rate at which glucose is made from proteins and the liver. In these two ways, glucagon increases blood surgar.
Diabetes Mellitus
When the pancreatic islet cells fail to produce enough insulin, glucose isnot available to the cells to be oxidized (catabolized) for energy.
Intead, the sugar remains in the blood and then must be removed by the kidneys and excreted in urine.
It is the most common endrocrine disorder. Diabetes is divided into 2 main types.
Insulin dependent, and non insulin dependent.
Insulin dependen diabetes mellitus (IDDM):
Is less common but more severe. It is also known as type 1. This disease usually appears before the age of 30 and is brought on by an autoimmune (self) destruction of the insulin producing cells in the islets. People with this type need close monitoring.
Non Insulin Dependent Diabetes Mellitus (NIDDM):
Or type II diabetes) usually occurs in adults, but is now frequently been seen in children. It is typically associated with overweight children and adults. This diabetes is controlled by diet, exercise and oral medication, although in stressful times can be injected.
Gestational Diabetes
Is brought on from pregnancy, usually goes away once the baby is born, and is usually affected to women that have diabetes in the family.
Typical signs of diabetes:
Polydipsia (excess thirst), polyuria (excessive urination), and polyphagia (an excess of eating), all brought on by high glucose in the blood and abnormal metabolism.
Androgens
All male hormones are classified
Testerone
The main male hormone produced by the testes.
Estrogen
Female hormone produced by the ovaries.
Progesterone
the other hormone produced by the ovaries, to assist in the normal development of pregnancy (gestation).
Thymus Gland
is a mass of lymphoid tissue that lies in the upper part of the chest superior to the heart.
This gland is important in the development in immunity.
Thymosin (part of the thymus gland)
assists in the maturation of certain white blood cells known as T cells (T lymphocytes) after they have left the thymus gland and taken up residence in lymph nodes throughout the body.
Pineal Gland
is a small, flattened, coneshaped structure located posterior to the midbrain and connected to the roof of the third venticle. The pineal produces Melatonin, during dark periods. little hormone is produced during the daylight hours.
mylelin sheath
some axons are covered with a fatty material called myelin that insulates and protects the fiber.
Schwann cells (PNS)
in the PNS, this covering is produced by special connective tissue cells called shwann cells that wrap around the axon like a jelly roll depositing layers of myelin.
Nodes
when a sheath is complete, mall spaces remain between the individual cells, these are the tiny gaps, they are important in speeding the conduction of nerve impulses.
The structural division of the nervous system that includes the cranial nerves.
Peripheral nervous system (PNS).
The structural division of the nervous system that includes the brain?
Central nervous system
Effector
Any tissue or organ that carries out a command from the nervous system, all of which are muscles or glands.
Somatic nervous system
Is controlled voluntarily(by concious and will) and all its Effectors are skeletal muscles.
Automatic Nervous system
Is the involuntary division of the nervous system. Making refernce to its automatic activity. It is also called the Visceral Nervous System, because it controls smooth muscle, cardiac muscle and glands. Much of which make up the soft body organs, the viseral.
Biofeedback
People can control involuntary functions, such as B/P, heart rate, breathing, by this technique.
Sympathetic and Parasympathetic systems
Are subdivisions of the Automatic Nervous system.
Bundles of fibers located within the PNS
Nerve
Tract
A similar grouping, (bundle of nerves) but located within the CNS.
Sensory Neurons, also called Afferent neurons
Neurons that conduct impulses to the spinal cord and brain.
Motor Neurons, also called efferent neurons
those cells that carry impulses from the CNS out to muscles and glands.
interneurons, also called central or association neurons
neurons that relay information within the CNS
Sensory (afferent) Nerves
Cranial nerves contain only sensory fibers conducting impulses toward the brain.
Motor (Efferent) Nerves
A few of the cranial nerves contain only motor fibers conducting impulses away from the brain.
Mixed Nerves
Most of the cranial nerves and ALL of the spinal nerves contain both sensory and motor fibers.
Effector
any tissue or organ that carries out a command from the nervous system. All of which are muscles and glands.
Somatic nervous system
is controlled voluntarily (by conscious will) and all its effectors are skeletal muslces.
Autonomic nervous system (ANS), also called the viseral nervous system.
the involuntary division of the nervous system making refernce to its automatic activity.Also called the viseral nervous system because it controls smooth muscle, cardiac muscle, and glands, much of which make up the soft body orders, the viscera.
Neurons
the functional cells of the nervous system that are highly specialized cells. these cells have a unique structure related to their function.
Cell body
The main portion of each neuron, contains the nucleus and other organelles typically found in cells.
Dendrites (Nerve Fiber)
Threadlike fiber that extend out from the cell body and carry impulses across the cell. Dendrites function as receptors in the nervous system, they receive the stimulus that begins a neural pathway.
Axons (Nerve Fiber)
are neuron fibers that conduct impulses away from the cell body. These impulses may be delivered to a muscle, another neuron or to a gland. An Axon is a single fiber, which may be quite long and which branches at its ends.
Nodes (originaly, Nodes of Ranvier)
When the sheath is complete, small spaces remain between the individual cells, these gaps are called nodes.
Neurilemma
The outermost membranes fo the Schwann cells that form a thin coating.
Sensory neurons, also called Afferent neurons
Are neurons that conduct impulses to the spinal cord and brain.
Motot neurons also called Efferent neurons
those cells that carry impulses from the CNS out to muslcles and glands.
Terneurons, also called central or associated neurons
Neurons that relay information wihin in the CNS
Neuroglia
Cells that serve for support and protection. there are different types of neuroglia, each with specialized functions.
Protective
Support nervous tissue and bind it to other structures
Aid in repair of cells
Act as phagocytes to remove pathogens and impurities
regulate the composition of fluids around and between the cells.
The Reflex Arc
as the nervous system fuctions, it receives, interprets, and acts on both external and internal stimuli. The spinal cord is also a relay center for coordinating neural pathways. A complete pathway through the nervous system from stimulus response is termed reflex arc. The basic parts of the reflex arc is the receptor, sensory neuron, central nervous system, motor neuron, and effector.
Receptor (basic part of a reflex arc)
End of a dendrite or specialized cell that responds to a stimulus.
Sensory Neuron (basic part of a reflex arc)
Transmits a nerve impulse toward the CNS.
Central Nervous System (basic part of a reflex arc)
Coordinates sensory impulses and organizes a response, usually requires interneurons.
Motor Neuron (basic part of a reflex arc)
Carries impulses away from the CNS toward the effector, a muscle, or a gland.
Effector (basic part of a reflex arc)
A muscle or gland outside the CNS that carries our a response.
Neurotransmitters (the main ones)
epinephrine, also called (adrenaline), norepinphrine, or (noradrenaline), and acetylcholine.
Dorsal Horns and Ventral Horns
the internal gray matter is arranged so that a column of gray matter extends up and down dorsally, on on each side, another column is dound in the ventral region on each side. These 2 columns give the H shaped appearance in cross section.
Gray Commissure
the bridge of gray matter that connect the right and left horms.
Central Canal
in the center of the Gray Commissure is a small channel that contains cerebrospinal fluid, the liquid that circulates around the brain and spinal cord.
Posterior Median Sulcus
A narrow groove, divides the right and left portions of the posterior white matter.
Anterior Median Fissure
A deeper groove, seperates the left and right protions of the anterior white matter.
Asending Tracts
Sensory (Afferent) impulses entering the spinal cord are transmitting toward the brain in acending tracts of the white matter.
Descending Tracts
Motor, (Efferent) impules traveling from the brain are carried in descending tracts toward the peripheral nervous system.
Spinal Reflex
a simple reflex arc that passes through the spinal cord alone and does not involve the brain.
Simple Reflex
is a rapid, uncomplicated, and automatic response involving very few neurons.
Stretch Reflex
is which a muscle is stretched and responds by contrating.
monoplegia
paralysis of one limb
Diplegia
paralysis of both upper and lower limbs
Paraplegia
Paralysis of lower limbs
Hemiplegia
Paralysis of one side of the body
Tetraplegia or quadriplegia
paralysis of all four limbs.
Plexuses
each spinal nerve continues only a short distance away from the spinal cord and then branches into small posterior divisions and larger divisions. the larger anterior branches interlace to form networks called plexuses, which then distribute branches to all parts of the body.
Cervical Plexus
supplies motor impulses to the muscle of the neck and receives sensory impulses from the neck and the back of the head. The phrenic nerve which activates the diaphragm, arises from this plexus.
Brachia Plexus
sends nemerous branches to the shoulder, arm, forearm, wrist, and hand. the Radial nerve emerges from the brachial plexus.
Lumbosacral plexus
supplies nerves to the pelvis and legs. the largest branch in this plexus is the sciatic nerve, which leaves the dorsal part of the pelvis, passes beneath the gluteus maxumus muscle, and extends down the back of the thigh. At the beginning it is nearly 1 inch thick, but it soon branches to the thigh muscles, near the knee, it forms two subdivsions that supply the leg and the foot.
Deratomes
is a region of the skin supplied by a single spinal nerve.
Peripheral Neuritis, or peripheral neurophathy
ia the degenration of nerves supplying the distal areas of the extremities. It affects sensory and motor function, causing symptoms of pain and paralysis. Causes include chronic intoxication, infectious diseases, metabolic diseases (Vit.defiecncy, starvation.
Sciatica
Is a form of peripheral neuritis characterized by serve pain along the sciatic nerve and its branches. The most common cause are rupture of a disk between the lower lumbar vertebrae and arthritis of the lower part of the spinal column.
Herpes Zoster
commonly known as shingles, is characterized by numerous blisters along the course of certain nerves, which are branches of the thoracic spinal nerves in the waist area.
Guillain Barre Syndrome
is classified as a polyneuropathy. A disorder involving many nerves. This is progressive muscle weakness due to the loss of myelin, with numbness and paralysis, which may involve the breathing muscles. The cause is unknown, but it is often followed by viral infections.
Cholinergic
A synapse is cholinergic if it uses acetylcholine as its neurotransmitter. Cholinergic means "related to the neurotransmitter acetylcholine," and is typically used in a neurological perspective. The parasympathetic nervous system is entirely cholinergic. Neuromuscular junctions, preganglionic neurons of the sympathetic nervous system, the basal forebrain, and brain stem complexes are also cholinergic.
Cerebrum
is the largest part of the brain. It is divided into right and left cerbral hemispheres by a deep grove called the longitudinal fissure. Each hemishphere is futher subdivided into lobes.
Diencephalon
is the area between the cerbral hemisheres and the brain stem. It includes the Thalmus and the Hypothalmus.
Brain Stem
connects the cerbrum and diencephalon with the spinal cord. The superior portion of the brain stem is the midbrain. Inferior to the midbrain is the pons, followed by the medulla oblongata.
Pons
connects the midbrain with the medulla, whereas the medulla connects the brain with the spinal cord through a large opening in the base of the skull (foramen magnum).
Cerebellum (little brain)
is located immediately below the posterior part of the cerebral hemisheres and is connected with the cerebrum, brain stem, and spinal cord by means of the pons. This word means little brain.
Meninges
are three layers of connective tissue that surround both the brain and the spinal cord to form a complete enclosure.
Dura Mater (Meninges)
Is the outermost of these membranes, its is the thickest and the toughest of the meninges. around the brain the dura mater is in 2 layers, the outer layer is fused to the bones of the cranium. In certain places, these two layers separate to provide venous channels, called dural sinuses, for the drainage of blood coming from the brain tissue.
Arachnoid (meninges) middle layer
this membrane is loosely attached to the deepest of the meninges by a weblike fibers, allowing a space for the movement of cerebrospinal fluid (CSF) between the two membranes.
Pia Mater, (Meninges) innermost layer
is attached to the nervous tissue of the brain and spinal cord and follows all the contours of these stuctures. it is made of a delicate connective tissue. It holds blood vessels that supply nutrients and oxygen to the brain and spinal cord.
Dural Sinus
Venous channels between the two outermost meninges
Arachnoid Villi
the area in which cerebrospinal fluid collects before its return to the blood
Choroid Plexus
The vascular network in the ventricle that forms cerebrospinal fluid.
Cerebral Hemisheres
each cerebral hemishere is divided into 4 visible lobes named for the overlying cranial bones. Frontal, Partiel, Temporal, and Occipital Lobes. In addition there is a small 5th lobe deep within each hemishere that cannot be seen from the surface, not much is known of this lobe (Insula).
Cerbebral Cortex
is the outer nervous tissue of the cerberal hemisheres is the gray matter that makes up the cerebral cortex.
Central Sulcus
which lies between the frontal and the partietal lobes of each hemishere at right angles to the longitudinal fissure.
Lateral Sulcus
which curves along the side of each hemishere and seperates the temporal lobe from the frontal and paretal lobes.
Basal Ganglia
Are masses of gray matter deep within the cerbrum that help regulate body movement and the muscles of facial expression.
Gyrus
an elevated protion of the cerbral cortex.
internal capsule
a band of white matter that carries impulses between the cerbrum and the brain stem
Cortex
the thin layer of gray matter on the surface of the cerbrum
corpus collosum
a band of myelinated fibers that bridges the two cerbral hemisheres.
the role of the thalmus
the two parts of the thalmus form the lateral walls of the 3rd ventricle. Nearly all sensory impulses travel through the masses of gray matter that form the thalmus. The role fo the thalmus is to sort out impulses and direct them to particular areas of the cerbral cortex.
contralateral
controls the opposite side. The right side of the brain controls the left side of the body, the left side controls the right side.
three subdivsion of the brain stem
the midbrain, the pons, and the medulla oblongata
Some functions of the Cerebellum
help coordinate voluntary muscles to ensure smooth orderly function. help maintain in balance, sitting, standing, walking, messages from the inner ear and from sensory receptors in tendons and muscles, help maintain muscle tone so that all muscle fibers are slightly tensed and ready to produce changes in position as quickly as possible.
Encephalon
Scientific name for the brain
Encephalitis
Inflammation of the brain
Epilepsy
A chronic brain disorder that can usually be diagnosed by electroencephalography, (EEG).
Hydrocephalus
A condition that may result from obstruction of the normal flow of cerebrospinal fluid.
Cerebrovascular Accident (CVA)
Damage to the brain tissue caused by a blood clot, ruptured vessel, or embolism.
Expressive Aphasia
the ability to speak or write
Receptive Aphasia
The ability to understand written or spoken language
glioma
a brain tumor derived from neuroglia
Alzheimer Disease
A dengeneration brain disorder associated with the development of amyloid
amyloid
an abnormal protein, and a tangling of neuron fibers that prevents communication between cells
multi infarct dementia
represents the accumulation of brain damage resulting from chronic ischemia (lack of blood supply) such as would be caused by a series of small stokes