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15 Cards in this Set
- Front
- Back
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Anemic
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dec. in red blood cells-leads to inability to transport oxygen
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Average blood volume of an adult?
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=about 5 liters or 8% body wt.
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Plasma=55% by vol.
(Blood Composition) |
-H2O, amino acids, proteins, carbohydrates, lipids, vitamins, hormones, electrolytes, cellular wastes
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Formed Elements+45% by col.
(Blood Composition) |
-Erythrocytes (RBC'S)=99% of Packed cell volume(PCV)
-Leucocytes (WBC's) is less than or = to 1% -Platelets |
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The process through which Hemocytoblasts(stem cells) mature into all blood cell types & platelets
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COlONY STIMULATING FACTORS
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function of Biconcave discs(breathsaver)
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(f) surface area for diffusion, allows folding
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=33% by vol: Hemoglobin
-what's its function? |
to bond w/oxygen to yield oxyhemoglobin(bright red blood)
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Path note
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low blood oxygen(hypoxia), will inc. deoxyhemoglbin turning skin & mucous membranes blue (cyanosis)
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path note-what causes cyanosis?
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e.g, suffocation, poisonous gases, vasoconstriction of surface vessels due to cold.
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why do mature RBC's lack nuclei?
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f: inc. space for hemoglobin
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Lack of Nuclei results in:
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a. no mitosis in mature RBC's
b. no mitochondria-only glycolysis possible |
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P.N-Sickle cell disease
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an incorrect amino acid causes hemoglobin to sickle causing damming in small capillaries-tissue hypoxia
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Erythopoiesis
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production of red blood cells for several days
-life span=120 days |
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Action of erythropoietin
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stimulates red marrow to produce & release RBC"s into circulation (chart pg 560)
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Destruction of RBC"s
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1. damage/destruction occurs in capillaries
2. damaged RBC's rupture in spleen & liver. components phagocytized by macrophages 3. hemoglobin components recycled A. 4 polypeptide globin chains B. 4 heme groups |
