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ADRENALINE
Presentation Routes Dose |
1:1000
IM, Nebulised, IV in cardiac arrest 0.5mg (0.5ml of 1/1000) may repeat 5-10 minutly if clinically indicared <6 months 0.05mg in 0.05mls 6 months - 2 yrs 0.1mg in 0.1mls 2 - 5 yrs 0.2mg in 0.2mls 6 - 12 yrs 0.3mg in 0.3mls Repeted every 5 - 10 min if clinically indicated Croup = 5mg in 5mls nedulised, only once Adult Cardiac Arrest- I mg IV every 3 minutes IV onset 30 sec, peak 3-5min, duration 5-10min IM onset 30-90 sec, peak in 4-10min, duration 5-10min |
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ADRENALINE
Pharmacology & Action |
A naturally occuring catecholamine-sympathomimetic agent
Stimulates the ALPHA & BETA subdivisions of the synpathetic NS to produce effect ALPHA stimulation causes peripheral vasoconstriction BETA 1 stimulation causes increased cardiac contractility & stimulates conducting tissue (SA & AV node) BETA 2 stimulates bronchodilation & dilation of vessels in muscles |
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ADRENALINE
1. Presentation 2. Pharmacology & Action 3. Indications 4. Contraindicationa 5. Route of Administration 6. Dose 7. Side Effects 8. Precautions |
1:1000, 1.0mg in 1.0 ml ampoule
A naturally occurring catecholamine-sympathomimetic agent Stimulates the ALPHA & BETA subdivisions of the sympathetic NS to produce effect ALPHA stimulation causes peripheral vasoconstriction BETA 1 stimulation causes increased cardiac contractility & stimulates conducting tissue (SA & AV node) BETA 2 stimulates bronchodilation & dilation of vessels in muscles Cardiac Arrest including: V, VT, PEA & Asystole Anaphylactic Shock Severe Shock Severe Asthma Severe Croup No contraindications IM- lateral thigh (preferably) or Deltoid IV-in cardiac arrest Nebulised- in croup |
Adullt Anaphylaxis:
-0.5mg in 0.5 mls (0.5 of 1:1000) -may repeat 5-10min if clinically indicated Child Anaphylaxis / Asthma: < 6 months 0.05mg in .05mls 6 months to 2 yrs 0.1mg in 0.1mls 2 – 5 yrs 0.2mg in 0.2mls 6 – 12 yrs 0.3mg in 0.3mls -may repeat every 5-10min if clinically indicated Adult Cardiac Arrest: -1mg IV every 3minutes Croup -5mg / 5mls nebulised, only once Side Effects: -Sinus Tachycardia -Supraventricular Arrhythmias -Ventricular Arrhythmias -Hypertension -Pupil dilation, Tremmor, Anxiety, Palpitations Precautions: But LIFE SAVING Adrenaline comes first -Angina -Acute Myocardial Ischemia -Acute Left Heart Failure -Exclude Cardiac causes of wheezing in patients >50 -Severe Hypertension |
