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17 Cards in this Set
- Front
- Back
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Zolpidem (Ambien)***
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GABAa Non-BZ Sedaive
Biphasic release (1st --> sleep; 2nd --> stay asleep) No hangover next day |
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Zaleplon (Sonata)***
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Selective based on binding to a1-subunit
Optimal drug for pt walking in the middle of the night Short t1/2 (1.4hr) so great for those who wake up & can't go back to sleep (out of your system before am) Limited hangover next am |
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Mirtazapine (Remeron)
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H1 blocker for depression
ALSO can help pt fall asleep & inc appetite (little old lady whose husband died) |
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Flumazenil (Romazicon)***
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BZ antag
Can cause seizure in pt on TCA Will get w/drawal in BZ-dependent pt |
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Escitalopram (Lexapro)***
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SSRI of choice
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Fluoxetine (Prozac)***
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AVOID.
Long t1/2 (6d) so wash out time is SLOW (>1mo) & has a ton of drug interactions. (inc risk of serotonin syndrome) |
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Serotonin Syndrome***
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Mental status changes
Autonomic instability NM aberrations GI sx Diff from neuroleptic malignant syndrome -- no muscule rigidity or CPK elevation Tx: BZ + Cyproheptadine |
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Fentanyl (Duragesic)
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Opiod anesthetic (&analgesia)
SE: constipation & resp depression DOC of anesthesiologist addiciton |
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Propofol
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PO GABA pre-anesthetic
Euphoria is unbelievable (high abuse) Induces & maintains day surgery Rapid recovery Blocks broncoconstriction CV & resp depression |
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Xanax
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Tx pain d/o through GABA BZ anxiolytic effect
Addictive! |
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Baclofen
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TX for EtOH therapy
GABAb Ag |
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Vigabatrin
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GABA transaminas-I
TX for inhalent abuse |
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Valium
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GABAa BZ anxiolytic
Blocks resp. depression No synergy w/ EtOH DOC IV for status epilepticus |
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Sonata
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Non-BZ
For pt who wake up in the night Short t1/2 |
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Prazosin
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A1 blocker
PTSD night mare TX |
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Klonopin
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GABAa BZ anxiolytic
BZ OF CHOICE for anxiety --give short term w/ SSRI |
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Lorazepam (Ativan)
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TX aggressive pt in ER
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