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23 Cards in this Set
- Front
- Back
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What is a fusion inhibitor that disrupts gp41 conformational change?
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Enfuvirtide, T-20
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What is fusion inhibitor that acts by binding to CXCR4 and prevents gp41 interaction?
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AMD-3100
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What antiviral binds in place of "pocket factor" and ultimately blocks nucleic acid transfer thru the capsid pore?
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Pleconaril
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What antiviral acts by blocking M2 pore of virus so an acidic environment is not formed so HA conformation change doesn't happen and thus prevents uncoating?
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Amantadine, Rimantadine
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Amantadine and Rimantadine prevent uncoating of what virus?
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Influenza A
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Tromantadine is an ativiral that prevents uncoating of what virus?
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HSV
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What is an oral antiviral that prevents RNA synthesis of the Picornavirus small pox?
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Isatin-b-thiosemicarbazone (IBT)
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What is an IV antiviral that prevents RNA synthesis of Hepatitis A-C viruses and HPV?
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Type I Interferons (IFNalpha)
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What is the mechanism of Ribavirin?
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inhibits RDRP replication, serves as bases analogue of adenine or guanine, inhibits enzymes from adding 5-CAP t mRNA
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What antiviral is administered for Respiratory Syncytia Virus RSV) and HCV Influenza A?
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Ribavirin
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What is the role of Viral Thymidine Kinases (VTK)?
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brings it own kinases so the virus can grown in non-dividing cells by phosphorylating the cells nucleosides (VTK add FIRST phosphates)
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What is the antiviral action of Acyclovir?
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Viral Thymidine Kinase (VTK)
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What antiviral drug is used to treat Influenza A?
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1. Amantadine
2. Rimantadine 3. Zanamivir (Relenza) 4. Oseltamivir (Tamiflu) |
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What antiviral drug is used to treat the common cold/ picornaviruses?
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Pleconaril
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What antiviral drug is used to treat smallpox?
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IBT
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What antiviral drug is used to treat Chronic Hepatitis and HPV?
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Interferons
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What antiviral drug is used to treat RSV pneumonia?
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Ribavirin
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What antiviral is used as a topical treatment of HSV keratitis?
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Idoxuridine, Trifluridine
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What antiviral is used to tx Genital HSV, HSV encephalitis and VZV?
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Acyclovir
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What antiviral is given orally to treat VZV shingles?
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Famciclovir, Valacyclovir
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What antiviral is used to treat recurrent HSV cold sores?
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Penciclovir
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What antiviral is used to treat HBV?
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Adefovir
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What antiviral drug is used to treat CMV retinitis?
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Ganciclovir
Foscarnet Cidoflovir |
