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28 Cards in this Set

  • Front
  • Back
foscarnet (PFA)
inhibit HSV DNA pol and HIV-1 RT; SELECTIVE TOXICITY
docosanol
inhibit fusion of HSV envelope w/ host cell plasma membrane
fomivirsen
inhibit translation in CMV
acyclovir/valacyclovir
purine/pyrimidine analogs; activated by 1st viral and 2nd host kinases; selective activation; SELECTIVE TOXICITY
ganciclovir/valganciclovir
purine/pyrimidine analogs; activated by 1st viral and 2nd host kinases
penciclovir/famciclovir
purine/pyrimidine analogs; activated by 1st viral and 2nd host kinases
idoxuridine
purine/pyrimidine analogs; activated by host kinases only
vidarabine
purine/pyrimidine analogs; activated by host kinases only
trifluridine
purine/pyrimidine analogs; activated by host kinases only
ribavirin
purine analog; activated by host kinases only
cidofovir
purine/pyrimidine analogs; preactivated
zidovudine (AZT)
NRTI; SELECTIVE TOXICITY
didanosine
NRTI
lamivudine
NRTI
stavudine
NRTI
zalcitabine
NRTI
tenofovir
nucleoTIDE RTI, so preactivated
nevirapine
NNRTI; noncompetitive inhibitor
delavirdine
NNRTI; noncompetitive inhibitor
efavirenz
NNRTI; noncompetitive inhibitor
saquinavir
protease inhibitors
ritonavir
protease inhibitors
enfuvirtide
peptide mimetic of viral env protein gp41domain; blocks membrane fusion
amantidine
inhibits viral uncoating
remantidine
inhibits viral uncoating
zanamivir
neuramidase inhibitor; blocks viral release
oseltamivir
neuramidase inhibitor; blocks viral release