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13 Cards in this Set
- Front
- Back
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amantadine and rimantadine mechanism
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disrupts viral ucoating and assembly of components
influenza A and C |
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zanamivir and oseltamivir mechanism
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competitive inhibitors of neuraminidase
influenza A and B |
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acyclovir mechanism
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inhibits viral DNA synthesis
lethal synthesis required Herpes I and II VZV EBV |
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fomivirsen mechanism
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antisense to mRNA of CMV
fomivirSEN antiSENse CMV retinitis in AIDS last resort |
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foscarnet
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competitive inhibitor of viral DNA polymerase
NO lethal synthesis required |
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ribavirin mechanism
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increases RNA virus mutation rate
use in RSV mutagenic, teratogenic and embryotoxic in both men and women |
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Zidovudine (AZT) mechanism
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inhibits reverse transcriptase
dowager's hump bone marrow effects fat redistribution lactic acidosis |
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tenofovir mechanism
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nucleotide reverse transriptase inhibitor
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efavirenz mechanism
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non nucleoside reverse transcriptase inhibitor
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-navir
ex saquinavir mechanism |
protease inhibitor (inhibits HIV aspartic protease enzyme)
can cause hyperlipidemia and hyperglycemia |
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enfuvirtide mechanism
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fusion inhibitor (GP41)
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maraviroc mechanism
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CCR5 receptor blocker
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raltegravir
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HIV integrase strand transfer inhibitor
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