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38 Cards in this Set
- Front
- Back
Second generation antipsychotics |
Clozapine (clorazil) *can cause agranulocytosis Need a WBC count
Risperdone (risperdal) Olanzapine (zyprexa) Ziprasidone (geodon) Paliperidone (invega) Iloperidone (fanapat) Asenapine (saphris) Lurasidone (latuda) |
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Third generation antipsychotics |
Aripiprazole (abilify) |
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Mechanisms of action for Antipsychotics |
Block receptors for the neurotransmitter dopamine First generation have more side effects Third generation is a dopamine system stabilizer |
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First generation antipsychotics |
Chlorpromazine (Thorazine) Perphenazine (Trilafon) Fluphenazine (Prolixin) *depot injection Thioridazine (Mellaril) *May lengthen the QT interval causing cardiac dysrhythmias Mesoridazine (Serentil) *may lengthen the QT interval causing cardiac dysrhythmias Trifluoperazine (stelazine)
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Side effects of antipsychotics |
Extrapyramidal symptoms Neuroleptic malignant syndromes Tardive Dyskinesia Dry mouth, blurred vision, urinary hesitation or retention. |
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Antidepressant drugs (what do they treat) |
Used to treat major depressive illness, anxiety disorders and the depressed phase of bipolar disorder and psychotic depression. Treat chronic pain, migraine headaches, sleep apnea, panic disorder and eating disorders |
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SSRIs |
Fluoextine (Prozac) Fluvoxamine (Luvox) Paroextine (Paxil) Sertraline (Zoloft) Citalopram (Celexa) Escitalopram (Lexapro) |
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Cyclic compounds (anti-depressants) |
Imipramine (Tofranil) Desipramine (Norpramine) Amitriptyline (Elavil) Nortriptyline (pamelor) Doxepin (Sinequan) Trimipramine (Surmontil) Protriptyline (Vivactil) Maprotiline (Ludiomil) Mirtazapine (Remeron) Amoxapine (Asendine) Clomipramine (Anafranil) |
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Other antidepressant compound meds |
Bupropion (Wellbutrin) *can cause seizures Venlafaxine (Effexor) Desvenlafaxine (pristiq) Trazadone (desyel) *may cause priapism Nefazodone (serzone) *may cause life threatening liver damage Duloxetine (cymbalta) |
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MAOIs |
Pheneizine (Nardil) Tranylcpromine (parnate) Isocarbixazid (marplan) |
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Mechanism of action for antidepressants |
Major interaction in norepinephrine, dopamine, and serotonin in the brain |
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Side effects of SSRIs |
Anxiety, agitation, akathsia, nausea, insomnia, difficulty getting an erection and an orgasm, weight gain, sweating, headaches |
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Side effects of cyclics |
Dry mouth, constipation, urinary hesitancy, dry nasal passages, blurred near vision, agitation, sexual dysfunction, tachycardia, weight gain |
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Side effects of MAOIs |
Daytime sedation, insomnia, weight gain, sexual dysfunction, orthostatic hypotension. |
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Inhibition of MAOIs results in.... |
Increased serum tyramine levels which lead to hypertension, hyperpyrexia, tachycardia, tremulousness, and diaphoresis. |
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Serotonin syndrome can occur when..... |
Taking an MAOI and a SSRI at the same time or too close to the end of each's therapy. |
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Symptoms of Serotonin syndrome |
Agitation, sweating, fever, tachycardia, hypotension, coma, and even death. |
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When should SSRIs be taken |
In the morning unless sedation is a problem |
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How many hours after can a dose of SSRI be taken |
Up to 8 hours |
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How many hours after can a dose of cyclic be taken |
Up to 3 hours |
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Foods to avoid while taking MAOIs |
Food with tyramine, (cheese, beer, aged meats) |
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Mood stabilizing drugs |
Used to treat bipolar disorder by stabilizing the clients mood preventing or minimizing the highs and lows and treating acute episodes of mania |
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Types of mood stabilizing drugs |
Lithium Anticonvulsants.... Lamotrigine Carbamzepine (Tegretol) *can cause aplastic anemia and agranulocytosis Valporic acid (depakote) *Can cause hepatic failure Gabapentin (neurontin) Topiramate (topamax) Oxcarbazepine (trileptal) Lamotrigine (lamictal) |
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Mechanism of action for lithium |
Lithium normalizes the reputable of certain neurotransmitters such as serotonin, norepinephrine, acetylcholine, and dopamine. |
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Mechanism of action for valporic acid (depakote) and topiramate (topamax) |
Known to increase levels of the inhibitory neurotransmitter GABA |
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Side effects of lithium |
Moms nausea, weight gain, acne, vomiting, muscle weakness, lack of coordination, acne, anorexia, metallic taste in mouth. |
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Anti-anxiety drugs (anxiolytics) |
Used to treat anxiety and anxiety disorders, insomnia, OCD, depression, PTSD and alcohol withdrawal. |
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Benzodiazepines |
Alprazolam (Xanax) Chlordiazepoxide (Librium) Clonazepam (Klonopin) Diazepam (Valium) Flurazepam (Dalmane) Lorazepam (Ativan) Oxazepram (Serax) Tamezepam (Restoril) Triazolam (halcion) |
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Mechanism of action of anxiolytics |
Mediate the actions of the amino acid GABA |
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Side effects of benzodiazepines |
Physical dependence, drowsiness, sedation, poor coordination, impaired memory, and clouded sensorium |
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Non-benzodiazepines |
Busprione (buSpar) |
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Side effects of non-benzodiazepines |
Dizziness, sedation, nausea, headache |
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Alcohol and anxiolytics |
Do not intake large amounts of alcohol while on them |
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Amphetamines (stimulant drugs) |
Used to treat ADHD in children and adolescents and narcolepsy |
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types of amphetamines (stimulant drugs) |
Methylphenidate (Ritalin) Amphetamine (Adderall) Pemoline (Cylert) *can cause liver failure in four weeks from beginning therapy. Atomoxetine (stratter) |
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Mechanism of action for amphetamines (stimulant drugs) |
They act by causing the release of norepinephrine, serotonin, and dopamine. They also block the reuptake of these transmitters |
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Side effects of amphetamines (stimulant drugs) |
Anorexia, weight loss, nausea, irritability, dizziness, dry mouth, blurred vision, and palpitations. Growth and wait suppression occurs in children |
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While taking amphetamines avoid.... |
Caffeine, chocolate and sugar. Potential for abuse is high with amphetamines, may lead to dependence |