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11 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Chlorpromazine
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classical
SidEf- extra pyramidal side effect (EPS), sedation, HypoTens, gynecomastia, hypothermia, anticholinergic effect, hypersensitivity reaction, jaundice. |
receptor affinity
D1 ++ D2 +++ alfa +++ H1 ++ mACh ++ 5HT2 ++ |
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Thioridazine
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classical
SidEf- extra pyramidal side effect (EPS), sedation, HypoTens, gynecomastia, hypothermia, anticholinergic effect, hypersensitivity reaction. lower extrapyramidal side effect. |
receptor affinity
D1 + D2 ++ alfa +++ H1 + mACh ++ 5HT2 ++ |
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Haloperidol
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classical
SidEf- strong extra pyramidal side effect (EPS), HypoTens, gynecomastia, hypothermia, few anticholinergic effect, hypersensitivity reaction. |
receptor affinity
D1 + D2 +++ alfa ++ H1 - mACh +\- 5HT2 + |
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Flupenthixol
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classical
SidEf- extrapyramidal side effect, slight sedation & HypoTens, gynecomastia, restlessness. |
receptor affinity
D1 ++ D2 +++ alfa ++ H1 ++ mACh - 5HT2 +++ |
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Sulpiride
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Atypical
SidEf- low extrapyramidal side effect, sedation, gynecomastia. poorly absorbed. |
receptor affinity
D1 - D2 +++ alfa - H1 - mACh - 5HT2 - |
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Clozapine
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atypical
SidEf- sedation, hypoTens, risk of agranulocytosis, seizures, salivation, anticholinergic SidEf, weight gain. efficacy in "treatment resistant" regular blood counts required. |
receptor affinity
D1 ++ D2 ++ alfa ++ H1 ++ mACh ++ 5HT2 +++ |
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Risperidone
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atypical
SidEf- extrapyramidal SidEf at high doses, hypoTens, weight gain. effective against negative symptoms. |
receptor affinity
D1 - D2 ++ alfa ++ H1 ++ mACh ++ 5HT2 +++ |
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Sertindole
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atypical
SidEf- low extrapyramidal SidEf & sedation, HypoTens, arrhytmias, weight gain, nasal congestion. effective against negative symptoms. t1\2- 3 days. ECG check advisable. |
receptor affinity
D1 - D2 ++ alfa ++ H1 - mACh - 5HT2 +++ |
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Quetiapine
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atypical
SidEf- low extrapyramidal SidEf, sedation, HypoTens, tachicardia, agitation, dry mouth, weight gain. act mainly on alfa rec. not fully evaluated. |
receptor affinity
D1 - D2 + alfa +++ H1 - mACh + 5HT2 + |
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name all the classical (typical) types of drugs
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Chlorpromazine
Thioridazine Haloperidol Flupenthixol |
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name all the atypical (new generation) types of drugs
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Sulpiride
Clozapine Risperidone Sertindole Quetiapine |
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