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9 Cards in this Set

  • Front
  • Back
Haloperidol, Fluphenazine, Thioridazine
Classical (Typical) Antipsych

Da blocker (+) Sx

SE: hyperprolactinemai, EPS, tardive dyskinesia (perminant, unethical LT)

No dry mouth!
Clozapine
Atypical Anti-psych

Agranulocytosis w/ rare blood d/o

Dec EPS/prolactinemia

Also hits some (-)sx w/ (+)

Yes: sedation & postural hypotension

1st gen, heavily used.
Olanzapine
Atypical
Best seller!

Causes most wt gain

No prolactin
Risperadone
Atypical -- AVOID

INC PROLACTIN & some EPS inc

Tx (+) and (-) sx

Da blocker
Ariprazole (Abilify)
Atypical

DA partial ag

If overactive, will tone them down.

NO postural hypotension, prolactin, or dry mouth***

YES sedation
Quetapine
Typical

No prolactin

Yes: sedation, postural hypotension, wt gain

Has mixed results clinically, b/c pt quit taking it.
Lorazepam (Ativan)***
Sedative
BZ (anxiolytic, muscle relaxant, hypnotic)

Rapid onset, short duration

Dec risk of haloperidol EPS

TX for agitated pt (common in all ER)***
TX Neuroleptic Malignant Syndrome (w/ Dantrolene + Bromocriptine)
What is a lethal combo?
Mixing atypical antipsch + BZ
General
Lost of off-lable use

All atypicals = wt gain (watch to metab syndrom...use metformin)***