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9 Cards in this Set
- Front
- Back
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What is the MOA of the ionophores? |
Lipophilic drug that binds cations and then crosses into the protozoa altering osmolarity leading to death |
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What drugs belong to the ionophores class? |
Monensin |
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What is toltrazuril's MOA? |
Inhibits nuclear division and mitochondrial activity of protozoa in intracellular stages of lifecycle |
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What animals is toltrazuril used in and what is significant about its use in these animals? |
intensively raised animals (chickens, pigs, cattle) Very long meat WHPs Zero day milk WHPs |
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What antibiotics are also antiprotazoals? |
Potentiated sulphonamides Clindamycin Metronidazole |
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What is an example of a potentiated sulphonamide and what are they used against? |
Suphadiazine + trimethoprim Coccidiosis (production) and toxoplasmosis (SA) |
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What is clindamycin used for in SA and why is its dose significant? |
Toxoplasmosis Lower dose when used as an antiprotozoal than as an antibiotic (5x) |
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What is metronidazole used to treat?
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Trichomonas in birds and cats (Tricohomas an issue in cattle but not registered) Giardia in dogs |
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What drug is used in the treatment of babesiosis? |
Imidocarb |
