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19 Cards in this Set

  • Front
  • Back
Pt has ASA allergy, what do I use?
ADP receptor antagonist
prophalaxis of MI and arterial thromboembolism
COX inhibitor
Adverse Effect of ADP Receptor Antagonist
TP, neutropenia, bleeding, blood dyscrasias, agranulocytosis
risk of COX inhibitor when administered with other antiplatelets or anticoagulants
inc risk of bleeding
intermittent caludication (PVD) what do I use?
cilostazol
thrombocytosis 2ndary to myeloproliferative disorders, what do I use?
anagrelide
adjunct to anticoagulant therapy to prevent thromboembolism
dipyradimole
increases mortality in pts with CHF (don't use in pts with any heart disease)... what drug am I?
cilostazol
which tests for monitories PDE inhibitors?
AST/ALT, SCr, BUN, Plt count
Clot prophylaxis associated with surgery, venous/arterial procedures, and dialysis
Anti-Thrombin III enhancers
Dose-dependent half-life anticoagulant
Anti-thrombin III enhancer
Side effect of Anti-thrombin III enhancer
heparin-induced-thrombocytopenia and heparin-induced osteoporosis
aPTT goal and norm
50-70 sec
normal is 30-50 sec
wht to monitor when using anti-thrombin III enhancers?
H/H K+, SCr, Plts, AST/ALT
antithormbin III enhancers enhances inhibition of which factors?
2a, 9a, 10a, 11a, 12a, plasmin, and kallikrein
vitamin K inhibitors inhibit which factors
C, S, 7, 9, 10
what to use to monitor for vitamin K inhibitor? and what range is good?
INR (want range of 2-3)
thrombin inhibitors MOA?
free and clot-bound thrombin---> interfere with fibrin generation, plt aggregation, 5, 8, and C activation
Prophylaxis of DVT/PE in surgery patients?
factor Xa pts
fondaparinux