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32 Cards in this Set
- Front
- Back
Plavix has a drug interaction with which drug specifically? |
Phenytoin |
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Plavix is irreversible or reversible? |
Irreversible |
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Arthalgia is an AE of what antiplatelet therapy? |
Plavix |
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What effect does Prasugrel have on Warfarin? |
Increased bleeding risk |
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When is Prasugrel absolutely contraindicated? |
After CVA (stroke) and TIA |
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What type of patients is Prasugrel not recommended in? |
75> years or older and < 60kg |
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What antiplatelet is indicated for stroke reduction? |
Ticlid |
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What is a precaution/contraindication for Ticlid? (she said when you see Ticlid think this) |
Blood dyscarasias (meaning lab monitoring is required bc some blood counts will be off like neutropenia) Need CBC |
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In what antiplatelet is CBC essential? |
Ticlodipine |
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What is Dipyridamole indicated for? |
W/ Warfarin in post valve replacement |
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What is Dipyridamole's name brand? |
Persantine |
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What is the dosing of Dipyridamole? |
100 mg qid |
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What are 2 AE of Dipyridamole? |
Tired and dizzy |
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Aggrenox is what? |
Dipyridamole and ASA |
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When is Aggrenox indicated? |
Stroke prevention in pts w/ history of prior Ischemic events. CVA prevention |
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What is the dosage of Aggrenox? |
1 bid. (200/25mg caps) |
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What is the dosing of Pentoxifylline (Trental)? |
400 mg tid |
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Trental may increase levels of what? |
Theophylline |
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Name 2 important counseling points of Trental. |
Take with food. May see effects in 2-4 weeks, up to 8-12 weeks to see full effect. |
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What is the dosing of Cilostazole (Pletal)? |
100mg bid |
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What are two things that definitely interact with Cilostazole? |
Grapefruit Juice and Diltiazem |
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When should you take Pletal? |
Take at least 30 minutes before or 2 hours after a meal |
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What is an absolute contraindication for Pletal (Cilostazole)? |
CHF of any severity |
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When could one expect to see effects of Pletal? |
up to 2 weeks to see effects and 8-12 to see full effects |
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What are the tablet strengths of Warfarin? |
1, 2, 2.5, 3, 4, 5, 6, 7.5, 10 |
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What enzymes are responsible for metabolizing with warfarin? |
CYP2C9 and 3A4 |
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What drugs can increase the effectiveness of warfarin? |
BAMIF |
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Name 3 absolute contraindications to warfarin. |
Pregnancy, active PUD, Hemorrhagic tendencies |
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What are some counseling points of Warfarin? |
Avoid take as directed drugs, avoid alcohol, follow directions strictly |
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What two drugs are indicated for VTE and A fib? |
Warfarin and Pradaxa |
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What drug is a direct thrombin inhibitor? (ie it inhibits fibrinogen into fibrin) |
Pradaxa (dabigatran) |
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What is the dosing of pradaxa? |
150mg bid |