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12 Cards in this Set

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1. We use different drugs to treat different bugs based on:
a. What allergies the patient has
b. What the bug is sensitive to
c. The cost
d. The duration of therapy
2. Many antibiotics cause
stomach upset and diarrhea
4. What is a superinfection and how does that differ from a superbug?
Def of superinfection
Those that occur during or after administration
of antimicrobial therapy
– Most common with a broad spectrum
antibiotic that also affects normal flora
• Pseudomembranous colitis(infection of the large intestine (colon) with an overgrowth of Clostridium difficile bacteria.), Candidiasis (yeast infection)
superbug def,
A superbug is bacteria that doesn’t respond to standard antibiotics. It’s a bit analogous to putting on a Superman suit — all of our bullets bounce off it,
Some antibiotics can cause what?
superinfections
Why do we have superbugs?
Superbugs can be cultivated by the indiscriminate use of broad spectrum antibiotics.
6. Some drugs are toxic to the kidneys
a. Vancomycin
b. Aminoglycosides
Antifungals:
1. Remember LIVER and CYP450 system!!!!
?
Antifungals
•Prototype: Amphotericin B (Fungizone) is highly
toxic
What does flu drugs do?
Flu drugs do not stop the virus, but may shorten symptom time
Antivirals Couple of different types- :
1. Couple of different types- Influenza, herpesvirus, HIV
Similarity of HIV and TB
HIV is treated with multiple drugs at one time (just like TB!!)
.
The HIV drugs work in different ways to treat the virus
Basic concept of HIV treatment is to STOP REPLICATION of the virus