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15 Cards in this Set

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List the Penicillinase resistant drugs
Oxacillin
Cloxacillin
Dicloxicillin
Nefcillin
Which two penicillins are not renally cleared ?
Ampicillin and Nafcillin
Which drugs are used to treat Staph Aureus infections ?
The penicillinase resistant drugs (oxacillin, cloxacillin,dicloxicillin and nafcillin.
List the anti-psuedemonas penicillin drugs ?
Piperacillin
Ticarcillin
Carbenicillin
Mezlocillin
They are also known as the EXTENDED SPECTRUM ANTIBIOTICS
What organisms do the anti-psuedemonas drugs target ?
same as aminopenicillins PLUS psudedenomas
aeruginosa
enterobacter, proteus and many klebsiella
What are two broaad spectrum antibiotics ?
Ampicillin and Amoxicillin
What organisms are targeted by the broad spectrum antibiotics ?
H influenzae
E. Coli
Salmonella
Shigella...they ARE active against *some* gram negative, but NOT against BL
What are the most frequent side effects of the broad spectrum antibiotics ?
rash and diarhhea..rash more common, especially if given to someone with mono
Which of the broad spectrum antibiotics is preferred for oral therapy ?
Amoxicillin
Why is amoxicillin preferred for oral therapy ?
Is more acid resistant and produces less diarrhea because less remains unabsorbed in the intestine
What class of antimicrobials does ampicillin belong to and what is the preferred route of admin ?
Broad spectrum antibiotic
IV admin
What is the purpose of the beta lactamase inhibitors ?
They inhibit the action of the beta lactamase and therefore "protect" the penicillin and allow it do its job
What are the beta lactamase inhibitors ?
sulbactam, tazobactum and clavulanic acid
Are the beta lactamase inhibitors ever given on their own ?
no..they are combined
Augmentin = amoxicillin + clavulanate
Zosyn= piperacillin + tazobactam
Timentin = ticarcillin + clavulanate
Which drugs cause platelet dysfunction ?
Mezlocillin and Piperacillin