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8 Cards in this Set

  • Front
  • Back
what is an antimicrobial ?
They ara products which are effectively used in treatment of infections due to their selective toxicity.
selective toxicity is...... and it depends on .....
is the ability to kill or inhibit an invading MO without having a harmful effect on the host cells ..... and it depends on the existence of biochemical differences between the parasite and host cells.
what are antibiotics?
substances produced by various species of MO that suppress the growth of other MO.
the term is often used for synthetic antibacterials .
examples of synthetic antibacterials ....
Sulphonamides & quinolones.
Bacteriostatic means ...
Agents that arrest the growth and replication of bacteria ,thus limiting the spread of infection while body's immune system attacks,immobilizes and eliminates the pathogens.
eg. Sulphonamides
Bactericidal means ....
Agents that kill bacteria .
eg. Penicillin
What are the factors affect in selection of antimicrobial agents?
1- identity of MO
2- Susceptibility of MO to antimicrobial
3- previous exposure to antibiotics
4- Age
5- renal and hepatic function
6- site of infection
7- administration of other drugs
8- pregnancy
9- immunity status .
Antimetabolites are .....
Sulphonamidea and trimethoprim