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8 Cards in this Set
- Front
- Back
what is an antimicrobial ?
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They ara products which are effectively used in treatment of infections due to their selective toxicity.
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selective toxicity is...... and it depends on .....
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is the ability to kill or inhibit an invading MO without having a harmful effect on the host cells ..... and it depends on the existence of biochemical differences between the parasite and host cells.
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what are antibiotics?
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substances produced by various species of MO that suppress the growth of other MO.
the term is often used for synthetic antibacterials . |
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examples of synthetic antibacterials ....
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Sulphonamides & quinolones.
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Bacteriostatic means ...
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Agents that arrest the growth and replication of bacteria ,thus limiting the spread of infection while body's immune system attacks,immobilizes and eliminates the pathogens.
eg. Sulphonamides |
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Bactericidal means ....
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Agents that kill bacteria .
eg. Penicillin |
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What are the factors affect in selection of antimicrobial agents?
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1- identity of MO
2- Susceptibility of MO to antimicrobial 3- previous exposure to antibiotics 4- Age 5- renal and hepatic function 6- site of infection 7- administration of other drugs 8- pregnancy 9- immunity status . |
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Antimetabolites are .....
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Sulphonamidea and trimethoprim
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