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6 Cards in this Set
- Front
- Back
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Classes of Drugs
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HMG-CoA reductase inhibitors-"statins" awesome but terrible AE
Bile acid sequestrants-Bile has lots of lipids; uses bile to control cholesterol Niacin-Brings down cholesterol Fibric acid derivatives-absorb cholesterol Cholesteral absorption inhibitor (Zetia) |
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HMG-CoA Reductase Inhibitors "Statins"
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*Inhibit* HMG-CoA enzyme which decrease cholesterol production (lowering LDL)
Drug: atorvastatin/Lipitor (P) SE: GI disturbance, increase liver enzymes NrsConsiders: Must do liver lab, take @ night, drug can last up to one month |
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Bile Acid Sequestrants
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Gathers cholesterol and does not release it. (Decreases cholesterol absorption)
Drug: cholestyramine/Questran |
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Fibric Acid Derivatives
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Decrease synthesis of VLDL
Drug: gemfibrozil & clofibrate Generally well tolerated, GI complaints most common |
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Nicotinic acid/Niacin/Vitamin B3
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Effective treating most hyperlipidemias but needs Major Dose and must take w/ Antihistamine
Various Effects @ different doses low tolerance due to flushing, itching, peptic ulcer, diabetic intolerance |
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Nursing Considerations
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-Monitor liver and renal functions
-Monitor cholesterol levels -Give meds w/ evening meal -DO NOT CRUSH TABLETS -Adminsiter w/ 120-180mL of water -Eat raw vegies, fruit & bran, low fat diet -Moderate Exercise -Drink at least 2L water each day |
