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8 Cards in this Set
- Front
- Back
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Alpha 2 adernergic agonist
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MOA- inhibits sympathetic
Drug- Clonidine Treat- HTN does not reduce M/M ADR- Anticholinergic!!, Orthostatic hypotension |
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Alpha 1 blockers
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MOA- blocks alpha 1; vasodilates
Drug- Doxazosin, Tamsulosin (Flomax) All others end in -osin Treat: HTN, Benign Prostatic Hypertrophy, Raynauds Disease, Decrease M/M |
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Cardioselective B1- blocker
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MOA- blocks B1, decrease HR, BP
Drug- end in -olol Treat: w/ co-morbidities, reduce M/M of HTN ADR: hypotension, acute HF Note: "Acebutolel" not as effective cause "ISA" |
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Non-Selective Beta-blockers
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MOA: blocks B1/B2
Drugs: Propanolol (Increase lipophilic) Nadolol, Pindolol ADR: Hypotension, Peripheral vasoconstriction |
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Alpha1, beta1, beta 2 blocker
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MOA: blocks alpha 1, beta 1, beta 2
Drugs: Carvedilol Treat: HTN, HF, decrease M/M ADR: same as all other alpha 1, beta 1, beta blockers BUT NO reflex tachycardia |
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ACE- inhibitors
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MOA: inhibits conversion of angiostensin 1 into angiostensin 2
Drug: ---"pril" Treat: preferred drug to better M/M ADR: angiodema, hyperkalemia Drug Interactions- NSAIDs worsen renal function! |
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Angiostensin 2 receptor blockers
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MOA: ARBs bind and block angiostensin 2 receptor blockers
Treat: same as ACE ADRs: legs likely cause bradykinin related adverse effects Drugs: end in "sartan" |
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Calcium Channel Blockers
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MOA: vasodilators, inhibits calcium, "Pine CCBs stronger vasodilaters than cardiac CCB's"
Drug: Pine CCBs- end in "pine" Cardiac CCBs: diltizem, verapamil Treat: angina, B1 blockers, doesen't help with M/M ADRs: Pine CCBs- reflex tachycardia Cardiac CCBs- bradycardia, decrease cardiac output |
