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28 Cards in this Set

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Normal BP
Systolic <130mm
Hg Diastolic <85mm Hg
High Normal
add 10 to normal sys, 5 to normal dia
Hypertension
each stage add 20 to sys and 10 to dia
What is blood pressure
CO X SVR
cardiac output x systemic vascular resistance
Adrenergic agents MoA
Block the alpha 1-adrenergic receptors
RESULT: Decreased BP
Central - Acting Adrenergics...
...stimulate alpha2-adrenergic receptors
Name a Central-Acting Adrenergic
Catapres
Alpha 1 blockers are _____ ____
peripherally acting
Alpha 1 blocker relieve_______ and manage______
symptoms of BPH
severe CHF
Peripherally acting adernergic neuronal blockers are seldom used because of...
...frequent side effects
ACE Inhibitors are
Angiotensin-Converting Enzyme Inhibitors
ACE Inhibitors info
-large group of SAFE and effective drugs
-often used as first-line agents for CHF and hypertension
ACE MoA
-Aldosterone stimulates water and sodium resorption
-Results in increased blood volume, increased preload, increased B
ACE Inhibitors block the _____-_____ enzyme, thus preventing the formation of _______ __
angiotensin-converting
angiotensin II
They also prevent the breakdown of the _____ substance, _____
vasodilating
bradykinin
The result is decreased___ ___ ___, vasodilation and therefore ___ ___ ___
systemic vascular resistance (afterload)
decreased blood pressure
Name an ACE inhibitor
Vasotec
What is the drug type of choice in hypertensive pts with CHF
ACE Inhibitors
ACE side effects
dry non-productive cough
What is an upside of Angiotensin II Receptor Blockers (ARB's)
newer class
well-tolerated
don't cause coughing
ARB MoA
-Allow angiotensin I to be converted to angiotensin II, but block the receptors that receive angiotensin II
-Block vasoconstriction and release of aldosterone
Types of Calcium Channel Blockers
-Benzothiazepines
-Dihydropyridines
-Phenlalkylamines
CCB MoA
Cause smooth muscle relaxatio by blocking the binding of calcium to its receptors, preventing muscle contraction
Type of Benzothiazepine
Cardizem
Type of Dihydropyridine
Norvasc, Cardene
Calcium Channel Blockers are for...
...Angina
Hypertension
Dysrhythmias
Migranes
Diuretics do what...
Decrease the plasma and extracellular fluid volumes
Vasodilators do what...
directly relax arteriolar smooth muscle