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9 Cards in this Set
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- 3rd side (hint)
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Ketoconazole
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Req Gastric Acid for absorption
Causes Adrenal Insufficiency |
Imidazole
Chronic mucocutaneous Candidiasis |
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Posaconazole
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Approved in 06
Broad activity including Mucorales |
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Terbinafine aka Lamisil
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Rx for onychomycosis, nail infection
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5 flourocytosine, Ancoban
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Blocks DNA synth
can lead to colitis and pancytopenia |
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Voriconazole
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block ergosterol formation
can lead to visual alteration V for visual, photosensitive and skin rash |
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Itraconazole
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blocks ergosterol formation
can lead to HTN, edema and hypokalemia |
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Echinocandin aka CAPSOFUNGIN
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Inteferes with B13 glucan synthetase of fungal cell wall
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New ampho prep with lipids or within liposomes, Ambisome
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Reduces nephrotox bc binds to HDL receptors, no HDL in renal tubular cells
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Fluconazole
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Kills C. albicans very well
less toxic and broader coverage |
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