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24 Cards in this Set
- Front
- Back
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Ampho B deoxycholate |
Conventional form President med 60 minutes b4: Tylenol or nsaid Meperidine Benadryl or hydrocortisone NS boluses to dec nephrotoxicity Decreases K n Mg |
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Ambisome, Abelcet, Amphotec |
All lipid formulations of Amp B |
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Ancoban |
Flucytosine, 5-FC Cidal Converted to fluorouracil Use in combo with Amp B Myelosupression Increases SCr and BUN Hepatitis Covers yeast |
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Nizoral, Ketodan, Extina, Xolegel |
Ketoconazole Static Tablet,cream, foam, gel, shampoo Hepatotoxicity Increase LFTs |
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Diflucan |
Fluconazole Static Candida albicans Covers yeast Cleared renally Tablet, suspension, injection Preg D except when 150mg dose Preg C as a class |
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Sporanox, Onmel |
Itraconazole Tablet, capsule, solution Limited by DIs Yeasts and dimorphic Capsule and oral solution not interchangeable Solution taken without food |
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Vfend |
Voriconazole DOC for Aspergillosis Covers C. Glabrata and C. Krusei Shake suspension for 10 seconds and don't refrigerate Preg D Liver damage, visual disturbances QT prolongation and hallucinations Increase LFTs, SCr Photosensitive Caution driving at night |
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Noxafil |
Posaconazole Tablet, suspension and injection Take with food Tab and susp not interchangeable Correct K Ca and Mg Preg C Spectrum like Vfend plus Zygomycetes (mucor and rhizopus) |
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Cresemba |
Isavuconazonium Prodrug Spectrum like Noxafil Tk without regards to food Caution in hepatic impairment Requires and filter during administration due to possible particulates Preg C |
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Itraconazole and ketoconazole have ph dependent absorption Need acidity Take with a soda if on PPI or H2RA Space antacids by 2 hours |
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Posaconazole suspension cannot be used with PPI or H2RA |
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Cancidas |
Caspofungin Cidal Echinocandin Injection Preg C Hepatotoxicity w/ cyclosporine No renal adjusting renal adjusting |
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Mycamine |
Micafungin |
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Eraxis |
Anidulafungin Echinocandin Preg B |
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Echinocandins |
Cidal Spectrum of Candida, krusei, and glabrata and Aspergillosis Well tolerated Injectable only Increase LFTs, hypotension, nvd, dec K and Mg Preg c |
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Grifulvin V, Gris-peg |
Griseofulvin Systemic not favored much Preg X Photosensitivity Inducer...contraceptive avoidance |
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Lamisil, Terbinex |
Terbinafine Inhibits squalene epoxidase Topical, granules, tablet Can cause lupus SEs: HA and increased LFTs |
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Mycelex |
Clotrimazolw Troche/lozenge Thrush Let dissolve for 15-30 minutes Treatment for 14 days. 5 Troche/day Preg C |
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Bio-Statin |
Nystatin Suspension, tablet, cream Preg C Thrush |
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Candida albicans treatment |
HIV (-) and orapharyngeal only: fluconazole or (clotrimazole, nystatin) HIV (+) or esophageal or invasive: Fluconazole or Echinocandin or Amp B |
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Candida glabrata or Candida krusei treatment |
Echinocandins or Amp B |
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Aspergillus treatment |
Voriconazole, liposomal Amp B, isavuconazonium |
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Zygomycetes class (Rhizopus or Mucor) |
Amp B plus or minus posaconazole or isavuconazonium |
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Dermatophytes treatment |
Nail bed infection Confirm fungi prior to treatment Itraconazole, Terbinex, fluconazole |
