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25 Cards in this Set
- Front
- Back
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What is the MOA of Griseofulvin and what is it used for?
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disrupts the mitotic spindle
dermatophytes |
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What is the MOA of Amphotericin B and what is it used for?
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binds ergosterol in the fungal membrane, altering membrane permeability
antifungal |
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What is the MOA of Nystatin and what is it used for?
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binds sterols in the fungal membrane, altering membrane permeability
Candida antifungal |
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What is the MOA of the tazoles?
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inhibit ergosterol synthesis by inhibition of P450-dependent enzymes
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What are the azole antifungals?
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Fluconazole, Itraconazole, Voriconazole, Posaconazole (triazoles)
Ketoconazole, Clotrimazole, Enilconazole, Miconazole (imidazoles) |
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What is the topical azole antifungal?
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Enilconazole, acts on dermatophtes and filamentous fungi
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What is the MOA of terbinafine?
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inhibits squalene epoxidase to decrease ergosterol synthesis
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What is the MOA of lufenuron as an antifungal?
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inhibits chitin synthesis in fungal cell wall
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What is the MOA of flucytosine?
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converted to 5-fluorouracil in the fungal cell to disrupt protein and DNA synthesis
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What is the MOA of iodides?
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unknown, may stimulate host immune response or increase elimination of the organisms via skin and hair
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What is the MOA of Natamycin?
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similar to Amphotericin B, alters ergosterol in the cell membrane
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What are the antiprotozoal nitroimidazoles?
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metronidazole
tinidazole ronidazole benznidazole |
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What are the antiprotozoal benzimidazoles?
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albendazole
fenbendazole febantel |
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What are the nitrofuran antiprotozoals?
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nifurtimox
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What are the tetracycline antiprotozoals?
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Oxytetracycline
Chlortetracycline Doxycycline |
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What are the hydroxyquinolone antiprotozoals?
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Decoquinate
Atovaquone Parvaquone Buparvaquone |
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What are the thiamine analogs used as antiprotozoals?
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Amprolium
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What are the alkaloids used as antiprotozoals?
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Halofuginone
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What are the polyether ionophores used as antiprotozoals?
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Lasalocid
maduramicin monensin marasin semeduramicin salinomycin |
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What are the triazine derivative antiprotozoals?
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diclazuril
toltrazuril ponazuril |
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What are the sulfonamide antiprotozoals?
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anything that says sulfa at the beginning
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What are the dihydrofolate reductase inhibitors used as antiprotozoals?
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Trimethoprim
Ormethoprim Pyrimethamine (daraprim) |
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What are the lincosamides used as antiprotozoals?
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Clindamycin
Lincomycin |
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What are the azalides used as antiprotozoals?
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Azithromycin
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What are the nitrothiazole derivatives used as antiprotozoals?
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Nitazoxanide
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