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2 Cards in this Set
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Amphotericin B
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Polyene antifungal that binds ergosterol and punches holes in the fungal cell membrane.
Nephrotoxicity is dose limiting (active against most fungi including the yeasts and filamentous fungi) |
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Azoles
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Inhibit cytochrome p450 to block the conversion of lanosterol to ergosterol
Examples: ketoconazole, fluconazole, itraconazole, voriconazole and posaconazole |
