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29 Cards in this Set

  • Front
  • Back
SAE gabapentin
none
SAE lamotrigine
Rash, SJS, TEN, DIC arthritis
serious skin rxn for lamotrigine incr w *
more common w concom valproate
SAE levetiracetam
None
SAE oxcarbazepine
Hyponatremia more common elderly; rash
SAE tiagabine
Stupor, spike wave stupor
SAE topiramate
nephrolithiasis, open angle glaucoma, hypohidrosis
SAE zonisamide
Rash, renal calculi, hypohydrosis
non ser AE gabapentin
wt gain, periph edema, behavioral change
non ser AE lamotrigine
tic insomnia
non ser AE levetiracetam
irritability/behavior chg
non ser AE oxcarbazepine
none
non ser AE tiagabine
wkness
non ser AE topiramate
metab acidosis, wt loss, language dysfxn
non ser AE zonisamide
irrit, photosens, wt loss
newer AED affected by renal dz
gabapentin, levetiracetam, topiramate
newer AED affectd by liver dz
lamotrigine, zonisamide, oxcarbazepine, tiagabine
oxcarbazepine
Trileptal
300mg bid; max 1200mg/d
zonisamide
zonegran & generic
initial dose 100 mg daily. titrated q2wks in 100mg increments to 400-600 mg/d
tiagabine
Gabitril
in induced state: 4mg, can be titrated to 56 mg/day in 2-4 doses
non-induced: half dose
gabapentin
Neurontin
300-600 mg tid
newer AED that do NOT interact w OC
gabapentin, levetiracetam, tiagabine, zonisamide
newer AED intx w OC
OC decr lamotrigine
topiramate decr OC
oxcarbazepine decr EE
topiramate drug interax
incr haldol
decr li
decr digoxin
lamotrigine drug interax
induces glucuronidation
sl decr valproate
topiramate cyp interax
induces 3A4
inhib 2C19 --> incr DPH
oxcarbazepine AED intx
induces cyp3A4 & glucuronidation; inh 2C19
reduces LMC
incr dph or pb
Topiramate
Topamax
200 mg bid; started as 25 mg bid titrated wkly
non-epilepsy use for topiramate
migraine tx
50 mg bid