Antidysrhythmics

Front 1

quinidine gluconate
-trade
-class

Back 1

qunaglute dur tabs

class 1A antidysrhythmic

Front 2

quinidine sulfate
-trade
-class

Back 2

quinora

class 1A antidisrhythmics

Front 3

procainamide
-trade
-class

Back 3

pronestyl

class 1A antidisrhythmics

Front 4

disopyramide
-trade
-class

Back 4

Norpace

class 1A antidisrhythmic

Front 5

class 1A moa

Back 5

blocks sodium channels at SA node,
slows depolarization, prolongs refractory period
slows conduction throughout

Front 6

contraindications of quinidines

Back 6

qt complex, sick sinus syndrome, bundle branch block, liver failure, myesthenia gravis, digoxin use

Front 7

serious side effects of quinidines

Back 7

torsades de pointes, hypotension, agranulocytosis, chinconism

Front 8

four components of chinconinsm

Back 8

tenitis, hearing disturbance, visual disturbance, headache

Front 9

common side effects of quinidines

Back 9

headache, nausea, diarrhea, dizziness

Front 10

procainamide
quinidine
disopyramide
order of anticholenergicness

Back 10

procainamide is less anticholinergic than quinidine; quinidine is less antimuscarinic than disopyramide

Front 11

serious side effects of procainamide

Back 11

SLE, seizures, asystole, ventricular arrythmia, agranulocytosis

Front 12

common side effects of procainamide

Back 12

diarrhea

Front 13

serious adverse effects of disopyramide

Back 13

CHF, arrythmia, agranulocytosis, thrombocytopenia

Front 14

common side effects of disopyramide

Back 14

urinary retention (with BPH), constipation, dry mouth, worsened glaucoma

Front 15

lidocaine
-trade
-class

Back 15

xylocaine

class 1B antidysrhythmic

Front 16

class IB moa

Back 16

blocks Na channels
shortens repolarization, shortens refractory period
decreases irratability of diseased cardiac tissude

Front 17

lidocaine halflife

Back 17

20 minutes

Front 18

contraindications of lidocaine

Back 18

respiratory depression, amide-like anesthetics, hypovolemia

Front 19

common side effects of class IB

Back 19

tremor, dizziness, confusion

Front 20

serious side effects of class IB

Back 20

respiratory arrest, seizures, worsened arrythmia

Front 21

fleccainide
-trade
-class

Back 21

tambacor

class IC antidysrhythmic

Front 22

class IC moa

Back 22

slows depolarization of conducting tissue, used in emergent situations

Front 23

fleccainide halflife

Back 23

12-30 hours

Front 24

class IC contraindications

Back 24

none

Front 25

common side effects of flecainide

Back 25

dizziness, tremor, visual disturbance

Front 26

serious side effects of flecainide

Back 26

arrythmia, sinus node dysfunction, conduction block, decreased conduction velocity

Front 27

metoprolol
-trade
-class

Back 27

lopressor

class II antidysrhythmic

Front 28

contraindications of class II

Back 28

CHF, heart block, asthma/COPD, bradycardia

Front 29

common side effects of class II

Back 29

Somnalence, insomnia/depression, fatigue, vertigo

Front 30

serious side effects of class II

Back 30

Electrolyte imbalance, heart block, bradycardia, CHF

Front 31

amiodarone
-trade
-class

Back 31

cordarone

class III K+ channel blocker

Front 32

sotalol
-trade
-class

Back 32

betapace

class III K+ channel blocker

Front 33

dofetilide
-trade
-class

Back 33

tykosyn

class III K+ channel blocker

Front 34

amiodarone
-half life
-excretion
-specialty

Back 34

-half life up to 100 days
-excreted in bile
-acts in all 4 receptors because alters lipid bilayer

Front 35

class III contraindications

Back 35

sinus node dysfunction
2nd/3rd degree AV block
bradycardic syncope
thyroid disease

Front 36

amiodarone common side effects

Back 36

blue/gray skin
corneal deposits
arrythmia woresning
drug interactions with CYP450 enzymes

Front 37

serious side effects of amiodarone

Back 37

pulmonary toxicity
hepatotoxicity
thyroid disease

Front 38

class IV moa

Back 38

blocks Ca+ channels
slows depolarization
slows repolarization
prolongs refractory

Front 39

diltiazem
-trade
-class

Back 39

cardazem

class IV antidysrhythmic

Front 40

verapamil
-trade
-class

Back 40

calan

class IV antidysrhythmic

Front 41

class IV to treat

Back 41

reentrant paroxysmal ventricular tachycardia

Front 42

contraindications of class IV

Back 42

sinus bradycardia
heart block
ventricular tachycardia
atrial fibrilation
grapefruit juice

Front 43

class IV common side effects

Back 43

constipation
dizziness
nausea
hypotension
edema

Front 44

class IV serious side effects

Back 44

CHF
Severe hypotension
AV block
bradycardia