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55 Cards in this Set
- Front
- Back
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1st gen sulfonylureas end w/
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"amide"
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2nd gen sulfonlylureas end w/
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"G...ide"
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Meglitinides end w/
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"glinide"
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Bigaunides end w/
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Metformin
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Thiazolidinediones end w/
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"glitazone"
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a-glucosidase inhibitors
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acarbose
miglitol |
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insulin lispro (humalog)
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ultra short acting insulin
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insulin aspart (novolog) [BCF]
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ultra short acting insulin
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insulin glulisine
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ultra short acting insulin (approved for CSII pumps)
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regular insulin (novolin) [BCF]
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short acting insulin
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only insulin that can be give IV or IM
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regular insulin (novolin)
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isophane insulin suspension (NPH)
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intermediate acting insulin
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NPH humulin
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intermediate acting insulin
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NPH novolin [BCF]
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intermediate acting insulin
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insulin glargine (lantus) [BCF]
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long acting insulin
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onset, peak, and duration for ultra short acting insulin
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15 min
1-2 hrs 4 hrs |
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onset, peak, and duration for short acting insulin
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0.5-1 hr
2-4 hrs 8 hrs |
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onset, peak, and duration for intermediate acting insulin
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2 hrs
8 hrs 24 hrs |
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onset, peak, and duration for long acting insulin
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NA
NA 24 hrs |
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acetohexamide (dymelor)
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1st gen sulfonylurea
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chlorpropamide (diabinese)
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1st gen sulfonylurea
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tolazamide (tolinase)
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1st gen sulfonylurea
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tolbutamide (orinase)
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1st gen sulfonylurea
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1st gen sulfonylurea w/ an extremely long half-life
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chlorpropamide (may cause hypoglycemia)
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glipizide (glucotrol) [BCF]
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2nd gen sulfonylurea
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glyburide (diabeta/micronase) [BCF]
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2nd gen sulfonylurea
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glimepiride (amaryl)
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2nd gen sulfonylurea
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most potent 2nd gen sulfonylurea
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glimepiride
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2nd gen sulfonylurea not used if CrCl <50ml/min
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glyburide
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2nd gen sulfonylurea not used if CrCl <10ml/min
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glipizide
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2nd gen sulfonylurea rx to elderly
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glipizide
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repaglinide (prandin)
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meglitinide
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nateglinide (starlix)
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meglitinide
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antidiabetic agent used for pts w/ varying eating schedules
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meglitinide
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metformin (glucophage) [BCF]
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biguanide
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antidiabetic agent used for obese pts
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biguanide (metformin)
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absolute CI for metformin use
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SCr >1.5mg/dL
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pioglitazone (actos)
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thiazolidinediones
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rosiglitazone (avandia) [BCF]
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thiazolidinediones
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CI for thiazolidinediones use
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class III/IV heart failure and hepatic dysfunction;
do not start if baseline LFTs >2.5 ULN |
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will thiazolidinediones work w/ type I diabetes?
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no...must have insulin on board to work
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acarbose (precose)
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a-glucosidase inhibitors
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miglitol (glyset)
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a-glucosidase inhibitors
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CI for a-glucosidase inhibitors
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GI dysfunctions
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SE of a-glucosidase inhibitors
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GI disturbances (> carbs = > disturbances)
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which combination antidiabetic agent requires LFTs at baseline and q 2 mos x1 yr?
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rosiglitazone/metformin (avandamet) [BCF]
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how tx HbA1C at 7%?
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TLC
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how tx HbA1C at 7-8%?
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single oral agent
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how tx HbA1C at 9-10%?
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two or more oral agents
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which antidiabetic drug not given to elderly?
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metformin because of renal function (SCr >1.5mg/dL)
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what is only acceptable antidiabetic drug for pregnancy?
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insulin
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when do you add insulin tx to type II diabetes pts?
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after two drugs if not effective
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diabetic ketoacidosis common in which type?
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type I
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hyperosmolar nonketotic syndrome (HNKS) common in which type?
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type II
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what glucose levels expected in HNKS?
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>600mg/dL
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