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39 Cards in this Set

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  • Back
Most lipid soluble benzo
Diazepam (Vailium)
The active metabolite of Diazepam is
Oxazepam (Serax)
Class side effects of benzos
Irritability
hostility
vivid bad dreams
Rash
sexual function impairment
Indication of Chlordiazepoxide (Also give brand name)
Brand name - Librium

Used for alcohol withdrawal and anxiety
Tranxene
Clorazepate Dispotassium
Halezepam
Paxipam
Lorazepam
Ativan
What is the antidote for benzo overdose?
Flumazenil (Romazicon)
Alprazolam
Xanax
Prezepam
(What is special about this drug)
Centrax
It's a prodrug
Clonazepam
Klonopin
Which 2 benzos have the longest half-life? (Up to 100 hours)?
Flurazepam (Dalmane)
Tranxene (Chloraxepate)
What are 4 nonbenzos that are also used for anxiety?
Propanolol
Buspirone
Antihistamines
Antidepressants
Hydroxyzine
(Give indication and brand name)
Atarax, Vistaril
An Antihistamine that is used for anxiety
Buspirone as a medication lacks what?
It lacks anticonvulsant, muscle relaxant, and hypnotic effects
When should you start Lithium if being treated for Bipolar psychosis?
You should treat it in the manic phase
What other medication besides Lithium is approved for the treatment of bipolar disorder?
Valproic Acid
What are some things to be cautious of when administering Lithium
Lithium has similar properties of potassium. Be cautious when using with diuretics.
Increase your salt intake (alters salt metabolism)
Thyroid activity should be monitored while on Lithium
What are some other foods that have tyramine in them?
Chianti wine
chocolate
aged cheese
soy sauce
raisins
chicken livers
What are 2 MAOIs that are not used as antidepressants? What are they used for?
Paragyline (Eutonyl) - An Antihypertensive

Furazolidone (Furoxone) - An Antibiotic
Name 3 MAOIs (Brand and Generic)
Tranycyclopromie (Parnate)
Isocarboxazid (Marplan)
Phenelzine (Nardil)
What are contraindications of TCAs in general?
Pregnancy
CHF
cardiovascular disease
Brand name and Indication of Imipramine
Tofranil
Used for depression and for enuresis in children
What are the TCA tertiary amines?
imipramine (Tofranil)
Amitriptyline (Elavil)
Clomipramine (Anafranil)
Doxepin (Sinequan)
What are the TCA secondary amines?
Nortriptyline (Aventyl)
Desipramine (Norpramin)
Amoxapine (Asendin)
Protriptyline (Vivactil)
Indication for Clomipramine?
OCD
Which TCA has a mixed antianxiety and antidepressant effect?
Doxepin (Sinequan)
Which TCA has the strongest anticholinergic effect?
Amitriptyline (Elavil)
1. The metabolite of Imipramine is ____
2. The metabolite of Amitriptyline is ____
1. Desipramine (Norpramin)
2. Nortriptyline (Aventyl)
Why is Vivactil more appropriate to use for withdrawn patients?
Because it has no sedative or tranquilizing properties
What are the 2 tetracyclic antidepressants?
Mirtazipine (Remeron)
Maprotiline (Ludiomil)
Which SSRI has the shortest half-life?
Fluvoxamine (Luvox)
Why are SSRIs used for Bulimia and not Anorexia?
Because patients that are Anorexic have very low levels of Serotonin and therefore SSRIs can't re-uptake it until they gain weight and increase their levels.
Which SSRI is the most activating?
Fluoxetine (Prozac)
Which is the most selective SSRI?
Citalopram (Celexa)
Side effects of Trazodone?
Priapism
Drowsiness
dizziness
Indications for Citalopram?
Diabetic neuropathy
Post stroke crying
Alcohol abuse
Venlafaxine
Effexor
What major side effects are seen in Amoxapine? (Give brand name as well)
Tardive dyskinesia
Neuroleptic Malignant Syndrome