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6 Cards in this Set
- Front
- Back
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Phenelzine
Tranylcypromine |
nonselective MAO inhibitors
AD require inhibition of MAO A Clinical use: 2-3rd line antidepressant Side Effects: ine and Chees syndrome w/ ephedrine and food w/ tyramine; serotonin syndrome w/ SSRI or SNRI |
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Fluoxetine(Prozac)
Sertraline(Zoloft) Fluvoxamine Paroxetine(Paxil) |
SSRIs: 5-HT uptake inhibitors
Clinical Use: Major Depression, Anxiety, Panic Disorder, OCD (less effective than TCA in severe depression) Side Effects: nausea, insomnia, sexual dysfunction, rash, leukocytosis, do NOT combine with MAOIs |
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Amitriptyline
Nortriptyline Imipramine Desipramine Clomipramine |
TCAS: NE/5-HT reuptake inhibitor, also antimuscarinic, antiH and antialpha-1
Clinical use: Unipolar depression, panic disorder Side Effects: sedation, hypotension, cardiac toxicity, cholinergic blockade, seizure, overdose with 10-20x daily dose |
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Reboxetine
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selective NE reuptake inhibitor
Depression |
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Venlafaxine
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selective 5-HT and NE reuptake inhibitor
antidepressant |
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Bupropion
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releases DA, stimulant
Antidepressant assoc w motor retardation (low dose) lowers discomfort of nicotine withdrawal |
