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7 Cards in this Set
- Front
- Back
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Aspirin
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Inhibits platelet release reaction by blocking platelet COX
Inhibits synthesis of TXA2, preventing aggregation and adherence |
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Dipyridamole
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Interferes with platelet function by increasing cAMP levels
Decreases platelet adherence to damaged endothelium Best used in combo with Warfarin |
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Ticlopidine/Clopidogrel
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Increases cAMP levels to inhibit platelet function
Reduces risk of stroke in patients who have experienced stroke precursors |
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Abciximab
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Antibody against IIb/IIIa receptor
Used with percutaneous angioplasty for coronary thromboses |
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Eptifibatide
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Peptide inhibitor of fibrinogen binding site on IIb/IIIa
Short duration Used for acute coronary syndrome and angioplastic intervention |
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Tirofiban
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Non peptide inhibitor of IIb/IIIa with action like Eptifibatide
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Warfarin
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Rapidly absorbed
95% bound to plasma Metabolized by liver and excreted in bile Prophylactic treatment against thrombi Vit K can be administered in case of hemorrhage |
