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17 Cards in this Set
- Front
- Back
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What are the natural anticoagulations
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Antithrombin, protein C, and protein S
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What are the proteins preventing clot formation
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antithrombin, protein C and protein S
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What is hemostatis
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STOPPING of beeding
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What is thombus
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blood clot
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What is thombosis
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formation of blood clot WITHIN a vessel
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What are the PRO-coagulations
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factors that promote clotting
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What are ANTIthombotics
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DRUGS that imputing thrombus formation and prevent thombosis
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What are anticoagulants
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factors that inhibit clotting
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What is finrinolysis
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mechanism that leads to dissolution of clot,
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What are drugs that dissolve clots are called
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thombolytics or fibinolytics
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What are the 3 main steps of platelet coagulation
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Platelet adhesions
Platlet activation Platelt aggregation |
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Under NORMAL conditions von Willebrand factors are circulating in the blood steam, what first happens when vascular injury occurs
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von Willebrand factors BINDS to the exposed sub endothelial cell collagen w/ one part, and OTHER part binds to Glycoprotein 1b receptor on surface of platlets
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Once the von Willebrand factors binds to sub endothelial cell collage, and receptor on platelets what happens
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platelet activation
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Once platelets are activated what happens
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Release of platelet granules, activation of IIB/IIIA receptors and flip flop of phospholipids
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What happens with activation of glycoprotein IIb/IIIa receptors
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allow it to bind to fibrinogen molecules, and fibrinogen then binds to another platelet
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After the platelet plug is formed, what ultimately happens
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fibrin mesh
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In the first step of fibrin formation, what happens
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VIIa is circulating in bloodsteam, comes in contact with TISSUE FACTOR expressed on extravasular cells`
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