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24 Cards in this Set
- Front
- Back
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Used to treat:
Leukemias Lymphomas Psoriasis RA breast cancer |
Methotrexate
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GI mucositis is dose limiting with infusion
BMD is dose-limiting with IV bolus |
5-FU, Capecitabine
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Brain tumors
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Carmustine
Lomustine |
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Profound, delayed BMD
CNS Renal Hepatic Pulomnary toxicities are all dose-limiting |
Carmustine
Lomustine |
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BMD
Hemorrhagic cystitis |
Cyclophophamide
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Veno-occlusive disease
Storong vesicant properties that produce ulcerations and necrosis |
Alkylating Agents
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Neurotoxicity is dose-limiting
BMD leads to neutropenia Fluid retention |
Docetaxel
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Ovarian cancer
Small cell lung cancer |
Topotecan
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Metastatic Colon Cancer
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Irinotecan
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BMD and Diarrhea are dose-limiting
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Irinotecan
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Stomatitis
Proctitis |
Dactinomycin
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ALL
Nonlymphocytic leukemias |
Daunorubicin
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Pulmonary toxicity is dose-limiting
Significant cutaneous toxicity pulmonary fibrosis |
Bleomycin
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Acute: Severe N&V
Anaphylactic rxns |
Cisplatin
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Delayed: Nephrotoxicity is dose-limiting
Neurotoxicty |
Cisplatin
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Testicular, ovarian and bladder cancer
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Cisplatin
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Peripheral neuropathy is dose-limiting
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Paclitaxel
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Treats breast and ovarian cancer
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Paclitaxel
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Neurological toxicity
Fatal if given intrathecally |
Vincristine
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Inactivated by xanthine oxidase
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6-Mercaptopurine
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Dose must be lowered when allopurinol is used
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6-Mercaptopurine
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AML, ALL, CML
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6-Thioguanine
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AML, ALL, NHL
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Cytarabine
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Myelosuppression
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Gemcitibane
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