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21 Cards in this Set
- Front
- Back
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beta-lactams action and examples
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Inhibit bacterial cell wall synthesis
Penecillin, amoxicillin |
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What are some beta-lactamase resistant antibiotics?
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Methicillin, Dicloxiciln, Flucloxacilin
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What are cephlasporins?
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Beta-lactams derivied from fungus cephlasporin.
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What are carbapenams?
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Beta-lactams that are broad spectrum from Gram -ve, penetrate CSF and are very expensive
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What are glycopeptides?
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Beta-lactams that are narrow spectrum for Gram +ve eg Vancomycin
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What are aminoglycosides?
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Bacteriocidal inhibitors of protein synthesis via binding the 30S of ribosomes.
Gram -ve |
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What are tetracyclines?
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Bacterialstatic inhibitors of protein synthesis via binding 30S of ribosomes
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What are Macrolides?
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Bacteriostatic inhibitors of proteins synthesis via binding 50S of ribosomes eg Erythromycin
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What are Quinolenes?
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Inhibit DNA synthesis via DNA gyrase or Topoisomerase. Eg Moxifloxalin, Ciprofloxalin
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What are Sulfonamides/Trimethoprim?
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Inhibite folate metabolite synthesis
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Treatment of Typical Pneumonia?
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Amoxycillin (beta lactams) or Erythromycin (macrolide) or newer Quinolones
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Treatment of Atypical Pneumonia? Eg mycoplasma, chlamydia?
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Macrolides, Tetracylines, Quinolones
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Treatment of Staph a Pneumonia?
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Amoxycillin base and or Erythromycin plus Flucloxicilin (lactamase resistant)
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Treatment of Legonella Pneumonia?
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Amoxycillin 500mg (beta lactams) or Erythromycin 1g - higher dose(macrolide) for 3 weeks
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Treatment of Anaerobe Pneumonia?
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Penicillin
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Treatment of Pseudomonas aeruginosa (hospital aquired)Pneumonia?
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Cephlasporins (b-lactam), aminoglycosides, quinolenes.
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Treatment of Viruses?
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Neuraminidase inhibitors
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Treatment of Dimorphic fungi, Aspergillus
Cryptococcus neoformans? |
Amphotericin, azoles,
and (recently) echinocandins |
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Treatment of Pneumocystis carinii?
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Sulfonamides (metabolites) + DHFR inhibitors, pentamidine, atovaquone
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Cytotoxic antibiotics?
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Bleomycin, Doxorubicin
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What antibiotics are used to treat TB?
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Isoniazid, Rifampicine, Ethambutol & Pyrazimamide
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