Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
List the types of Antibiotics |
Beta lactams - pencillins, cephalosporins, carbapenems Oxazolidinones Tetracyclines Macrolides Fluoroquinolones Aminoglycosides Glycopeptides Lincosamides Miscellanous/Metronidazole |
|
|
Classification based on site of action |
Cell wall - beta lactams - Glycopeptides DNA - Fluoroquinolones - Cotrimoxazole (sulfamethoxazole and trimethoprim) - Metronidazole Protein synth inhibition via 1. Ribosomal inhibition - Oxazolidinones - Tetracyclines - Macrolides - Aminoglycosides - Lincosamides 2. Prevention of RNA synthesis - Rifampicin |
|
|
Penicillins - Examples - Side effects |
Penicillin Amoxycillin Allergy Hepatotoxicity Neutropenia Decreased Platelet aggregation |
|
|
Cephalosporins - EG - Side effects |
Allergy Hepatotoxicity Neutropenia Increased Prothrombin Time |
|
|
Carbapenems |
- Imipenem Allergy Hepatotoxicity Neutropenia Increased Seizure risk |
|
|
Macrolides |
Erythromycin Erythro - inhibition of CYP3A4 Hepatotoxic Agranulocytosis |
|
|
Aminoglycosides |
Gentamicin Nephrotoxic NMB potentiation |
|
|
Fluoroquinolones |
Ciprofloxacin Teratogenic Tendinitis |
|
|
Glycopeptides |
Vancomycin Ototoxicity Red Man syndrome - hypotension and decreased contractility |
|
|
Tetracyclines |
Doxycycline Teratogenic, Hepatotoxic benign Intracranial hypertension GI irritation |
|
|
Oxazolidinones |
Linezolid Bone marrow suppression Exaggerated sympathomimetic effects for those on MAO |
|
|
Lincosamides |
Clindamycin NMJ potentiation |
|
|
Misc |
Metronidazole Sulfamethoxazole Rifampicin - enzyme inducer Trimethoprim Teratogenic Peripheral neuropathy |
