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26 Cards in this Set
- Front
- Back
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what are two methods to attack cell wall synthesis?
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PBP (transpeptidase) and peptidoglycan synthesis
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what is a glycopeptide (peptidoglycan synthesis)?
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vancomycin
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what are the four classes under PBP?
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penicillins, carbapenems, cephalosporins, monobactams
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what is vancomycin good for?
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gram positive cocci
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what are the three mechanisms of action of antibiotics?
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1. inhibit cell wall synthesis
2. inhibit DNA synthesis 3. inhibit protein synthesis |
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what is the drug that affects DNA synthesis?
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rifamycins
affects the DNA polymerase |
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what is a monobactam (name) and what is it good for?
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aztreonam
gram negative |
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what is an example of first generation cephalosporin, and what is it good for?
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cefazolin
gram positive cocci |
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what is an example of second generation cephalosporin?
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cefuroxime
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what is an example of third generation cephalosporin, and what is it good for?
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ceftazidime
gram negative |
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what is an example of a fourth generation cephalosporin?
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cefepime
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what is another name for penicillins?
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beta-lactamases
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what drug class is stable to beta-lactamases?
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carbapenems
(imipenem, meropenem) |
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what do tetracyclines do?
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they inhibit protein synthesis, 30S
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which classes are bacteriostatic?
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most of the classes that affect protein synthesis
(except the aminogycosides) |
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what are the two classes that affect the 30S protein synthesis?
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tetracyclines, aminoglycosides
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what are examples of aminoglycosides?
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streptomycin, gentamycin
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what are the three classes that affect the 50S protein synthesis?
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lincosamides, streptogramins, macrolides
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what classes are good for protozoa?
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tetracyclines, sulfonamides
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what are examples of macrolides?
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erythromycin, clarithromycin, azithromycin, telithromycin
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what are aminoglycosides good for?
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gram negative bacilli
gram positive cocci mycobacteria |
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what are tetracyclines good for?
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all bacteria, protozoa
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what are sulfonamides good for?
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gram positive/negative
intracellular branching protozoa |
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what is an example of a quinolone?
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ciproflaxin
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what are quinolones good for?
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gram negative
atypicals (chlamydia, mycoplasma, legionella) staphylococci |
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what are the four generations of cephalosporins?
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1. cef-A-zolin, ceph-A-lexin
2. cef-U-roxime 3. cef-T-azidime 4. cef-E-pime |
