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7 Cards in this Set
- Front
- Back
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7 groups of cell wall synthesis inhibitors
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P C C C M G B
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Beta lactams resistance
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Enzyme beta-lactamase catalyses hydrolysis of the B-lactam ring -> changes structure of the drug -> rendering it inactive
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How do B-lactamase inhibitors work
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Use kamikaze drugs which form an acyl enzyme complex - against which beta lactamase is ineffective
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Two examples of beta-lactamase inhibitors
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1) clavulanic acid
2) tazobactam |
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4 groups of protein synthesis inhibitors
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M A C T
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Aminoglycosides
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Bactericidal
G+, G- Prevent initiation complexes for protein synthesis - bind to 30s subunit in 70s ribosome Nephrotoxic Ototoxic (ear) |
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Inhibitors of DNA function
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Q M R C
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