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42 Cards in this Set

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VANCOMYCIN mech
inhibits peptidoglycan formation
BACITRACIN mech
inhibits peptidoglycan formation
PENICILLIN mech
binds to transpeptidase
CEPHALOSPORINS mech
binds to transpeptidase
AUGMENTIN mech
amoxicillin: binds to transpeptidase clavulonic acid: inhibits β-lactamase
CARBAPENEMS mech
inhibit peptidoglycan cross linking
MONOBACTAMS mech
inhibit peptidoglycan cross linking
VANCOMYCIN function
inhibit cell wall synth, inhibit peptidoglycan formation
BACITRACIN function
inhibit cell wall synth, inhibit peptidoglycan formation
PENICILLIN function
inhibit cell wall synth, inhibit peptidoglycan cross-linking
CEPHALOSPORINS function
inhibit cell wall synth, inhibit peptidoglycan cross-linking
AUGMENTIN function
inhibit cell wall synth, inhibit peptidoglycan cross-linking
CARBAPENEMS function
inhibit cell wall synth, inhibit peptidoglycan cross-linking
MONOBACTAMS function
inhibit cell wall synth, inhibit peptidoglycan cross-linking
VANCOMYCIN spect
narrow: g(+); staph
BACITRACIN spect
g(+)
PENICILLIN spect
varies, *see common pen chart*
CEPHALOSPORINS spect
broad: g(-)
CARBAPENEMS spect
VERY broad: g(-) & g(+)
MONOBACTAMS spect
~very broad: g(-) ~narrow: g(+)
VANCOMYCIN admin
parenterally
BACITRACIN admin
topical
CEPHALOSPORINS admin
cephalexin: oral cephazolin: im cefaclor: oral
CARBAPENEMS admin
i.v.
MONOBACTAMS admin
i.v.
VANCOMYCIN absorp
NO GI tract
BACITRACIN absorp
NO GI tract
PENICILLIN dist
NO CSF
CEPHALOSPORINS dist
cefotaxime & cefixime -->CSF
VANCOMYCIN term
renal excretion
PENICILLIN term
renal excretion
VANCOMYCIN tox
~nephrotoxic ~hearing loss
BACITRACIN tox
~nephrotoxic
PENICILLIN tox
~allergic rxn ~irritation @ injection site ~mild GI upset
CEPHALOSPORINS tox
~irritation @ injection site ~↓ bone marrow ~renal toxicity
CARBAPENEMS tox
mild GI upset
VANCOMYCIN other
~resistance = problem ~bactericidal
BACITRACIN other
~can give orally before bowel surgery ~bactericidal
PENICILLIN other
~β-lactam ~some = penicillinase sensitive ~bactericidal
CEPHALOSPORINS other
~good for pts w/penicillin allergy ~penicillinase resistant ~β-lactam ~bactericidal
CARBAPENEMS other
~given in combo w/cillistatin ~β-lactam imipenem meropenem ertapenem ~bactericidal
MONOBACTAMS other
aztreonam ~β-lactam ~bactericidal