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42 Cards in this Set
- Front
- Back
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VANCOMYCIN mech
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inhibits peptidoglycan formation
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BACITRACIN mech
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inhibits peptidoglycan formation
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PENICILLIN mech
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binds to transpeptidase
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CEPHALOSPORINS mech
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binds to transpeptidase
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AUGMENTIN mech
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amoxicillin: binds to transpeptidase clavulonic acid: inhibits β-lactamase
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CARBAPENEMS mech
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inhibit peptidoglycan cross linking
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MONOBACTAMS mech
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inhibit peptidoglycan cross linking
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VANCOMYCIN function
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inhibit cell wall synth, inhibit peptidoglycan formation
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BACITRACIN function
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inhibit cell wall synth, inhibit peptidoglycan formation
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PENICILLIN function
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inhibit cell wall synth, inhibit peptidoglycan cross-linking
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CEPHALOSPORINS function
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inhibit cell wall synth, inhibit peptidoglycan cross-linking
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AUGMENTIN function
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inhibit cell wall synth, inhibit peptidoglycan cross-linking
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CARBAPENEMS function
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inhibit cell wall synth, inhibit peptidoglycan cross-linking
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MONOBACTAMS function
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inhibit cell wall synth, inhibit peptidoglycan cross-linking
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VANCOMYCIN spect
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narrow: g(+); staph
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BACITRACIN spect
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g(+)
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PENICILLIN spect
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varies, *see common pen chart*
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CEPHALOSPORINS spect
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broad: g(-)
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CARBAPENEMS spect
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VERY broad: g(-) & g(+)
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MONOBACTAMS spect
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~very broad: g(-) ~narrow: g(+)
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VANCOMYCIN admin
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parenterally
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BACITRACIN admin
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topical
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CEPHALOSPORINS admin
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cephalexin: oral cephazolin: im cefaclor: oral
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CARBAPENEMS admin
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i.v.
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MONOBACTAMS admin
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i.v.
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VANCOMYCIN absorp
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NO GI tract
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BACITRACIN absorp
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NO GI tract
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PENICILLIN dist
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NO CSF
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CEPHALOSPORINS dist
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cefotaxime & cefixime -->CSF
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VANCOMYCIN term
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renal excretion
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PENICILLIN term
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renal excretion
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VANCOMYCIN tox
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~nephrotoxic ~hearing loss
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BACITRACIN tox
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~nephrotoxic
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PENICILLIN tox
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~allergic rxn ~irritation @ injection site ~mild GI upset
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CEPHALOSPORINS tox
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~irritation @ injection site ~↓ bone marrow ~renal toxicity
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CARBAPENEMS tox
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mild GI upset
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VANCOMYCIN other
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~resistance = problem ~bactericidal
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BACITRACIN other
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~can give orally before bowel surgery ~bactericidal
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PENICILLIN other
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~β-lactam ~some = penicillinase sensitive ~bactericidal
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CEPHALOSPORINS other
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~good for pts w/penicillin allergy ~penicillinase resistant ~β-lactam ~bactericidal
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CARBAPENEMS other
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~given in combo w/cillistatin ~β-lactam imipenem meropenem ertapenem ~bactericidal
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MONOBACTAMS other
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aztreonam ~β-lactam ~bactericidal
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